elimination by phagocytosis. In addition, the C5 convertase initiates the terminal phase of the complement system, leading to the assembly of the membrane...

Complement component 5 is a protein that in humans is encoded by the C5 gene. Complement component 5 is involved in the complement system. It is cleaved...

C5 convertase is an enzyme belonging to a family of serine proteases that play key role in the innate immunity. It participates in the complement system...

the complement system follows the same path regardless of the means of activation (alternative, classical, or lectin). C5-convertase cleaves C5 into...

Terminal complement pathway deficiency is a genetic condition affecting the complement membrane attack complex (MAC). It involves deficiencies of C5, C6,...

cleavage of complement component C5 by protease C5-convertase into C5a and C5b fragments. C5b is important in late events of the complement cascade, an...

The complement system, also known as complement cascade, is a part of the humoral, innate immune system and enhances (complements) the ability of antibodies...

vitronectin, two regulators of complement. The membrane attack complex is initiated when the complement protein C5 convertase cleaves C5 into C5a and C5b. All...

spinal nerve 5 Complement component 5, a protein of the complement system C5-convertase, an enzyme which splits C5 into C5b Complement component 5a, an...

immunity as a part of the complement system which eventuate in opsonisation of particles, release of inflammatory peptides, C5 convertase formation and...

Corvette C5-R is a grand touring racing car built by Pratt Miller and Chevrolet for competition in endurance racing. The car is based on the C5 generation...

Alternative-complement-pathway C3/C5 convertase (EC 3.4.21.47, complement component C3/C5 convertase (alternative), proenzyme factor B, properdin factor...

certain autoimmune disorders. In such cases treatment with the complement-inhibitory anti-C5 monoclonal antibody, eculizumab, is found to be highly effective...

syndrome. It is designed to bind to and prevent the activation of Complement component 5 (C5). Paroxysmal nocturnal hemoglobinuria is characterized by red...

response. In the classical and lectin pathways of complement activation, formation of the C3-convertase and C5-convertases requires binding of C2 to an activated...

for fragments of the complement system. C3, C4A, C4B, C4B-1, C5, FBLN1, FBLN2 Allergy Anaphylatoxin receptors Anaphylaxis Complement system Inflammation...

"RA101495, a subcutaneously administered peptide inhibitor of complement component 5 (C5) for the treatment of generalized myasthenia gravis (gMG): Phase...

"A" version of the Lockheed C-5 Galaxy, a large military transport aircraft C5 (disambiguation) This disambiguation page lists articles associated with the...

Francis L, Ravindranathan R, Bartlett DL (June 2013). "Inhibitors of C5 complement enhance vaccinia virus oncolysis". Cancer Gene Therapy. 20 (6): 342–50...

humanized monoclonal antibodies that target B cell malignancies and prevent C5 complement cleavage, respectively. Nayer, Ali; Ortega, Luis M. (2014). "Catastrophic...

binds to bacterial cell walls and dying human cells to stabilize the C3 and C5-convertase enzyme complexes to form an attack complex that lead to the lysis...

S2CID 25061446. Rawal N, Pangburn MK (March 2001). "Structure/function of C5 convertases of complement". International Immunopharmacology. 1 (3): 415–22. doi:10...

treatment of people with paroxysmal nocturnal hemoglobinuria. It is a complement component 5 (C5) inhibitor. Crovalimab was approved for use in China in February...

positions, 3) C5 binding sites, 4) private allelic residues. Additionally, the same study identified the expression of human complement C4 transcripts...

functioning as a terminal complement inhibitor. It binds to the complement C5 protein and inhibits activation of the complement system, a part of the body's...

diminish historian's view of aircraft." US Air Force, 4 April 2006. "Halt to C5 Program Sought After $50 Million Blaze". The Victoria Advocate. No. 165. Associated...

compounds with chemical formulae and CAS numbers, indexed by formula. This complements alternative listing at list of inorganic compounds. There is no complete...

"The development of atypical hemolytic uremic syndrome depends on complement C5". Journal of the American Society of Nephrology. 22 (1): 137–145. doi:10...

functioning as a terminal complement inhibitor. It binds to the complement C5 protein and inhibits activation of the complement system, a part of the body's...

"A Phase 3 Safety and Efficacy Study of Intravitreal Administration of Zimura (Complement C5 Inhibitor)" at ClinicalTrials.gov Portal: Medicine v t e...