Cannabinoid receptors, located throughout the body, are part of the endocannabinoid system of vertebrates– a class of cell membrane receptors in the G...

Cannabinoid receptor 1 (CB1), is a G protein-coupled cannabinoid receptor that in humans is encoded by the CNR1 gene. And discovered, by determination...

membrane-bound receptors. The discovery of the first cannabinoid receptors in the 1980s helped to resolve this debate. These receptors are common in animals...

The cannabinoid receptor 2 (CB2), is a G protein-coupled receptor from the cannabinoid receptor family that in humans is encoded by the CNR2 gene. It...

A cannabinoid receptor antagonist, also known simply as a cannabinoid antagonist or as an anticannabinoid, is a type of cannabinoidergic drug that binds...

endocannabinoids, which are neurotransmitters that bind to cannabinoid receptors, and cannabinoid receptor proteins that are expressed throughout the central...

Synthetic cannabinoids, or neocannabinoids, are a class of designer drug molecules that bind to the same receptors to which cannabinoids (THC, CBD and...

dose-dependent buildup of cannabinoids and related effects of cannabinoid toxicity the functionality of cannabinoid receptors in the brain and particularly...

Ki is the compound's binding affinity for the cannabinoid receptor type 1 (CB1) or cannabinoid receptor type 2 (CB2). Manera C, Tuccinardi T, Martinelli...

PMID 16968947. Hongfeng Deng. Design and synthesis of selective cannabinoid receptor ligands: Aminoalkylindole and other heterocyclic analogs. PhD Dissertation...

ECP-012A; Arvisol, Epidiolex) – cannabinoid receptor modulator, antioxidant, other actions CVN766 – Orexin receptor type 1 antagonist Deudextromethorphan...

inverse agonist for the cannabinoid receptor CB1 and was first-in-class for clinical development. Rimonabant is a selective CB1 receptor blocker and was discovered...

CB2 cannabinoid receptors, with some selectivity for CB2. It produces effects in animals similar to those of tetrahydrocannabinol (THC), a cannabinoid naturally...

GPR55, along with GPR119 and GPR18, have been implicated as novel cannabinoid receptors. GPR55 was identified and cloned for the first time in 1999. Later...

(also incorrectly known as 5-CL-ADB-A) is an indazole-based synthetic cannabinoid that has been sold online as a designer drug. MDMB-4en-PINACA was first...

"Delta9-tetrahydrocannabinol and endogenous cannabinoid anandamide directly potentiate the function of glycine receptors". Molecular Pharmacology. 69 (3): 991–97...

potent but nonselective full agonist for the cannabinoid receptor. It is part of the AM series of cannabinoids discovered by Alexandros Makriyannis at Northeastern...

lipase inhibitor Cannabidiol (CBD) – cannabinoid receptor modulator Cannabidivarin (CBDV; GWP-42006) – cannabinoid receptor modulator CMX-020 – TRPV1 modulator...

Fernández-Ruiz, J. J. (1999-09-01). "Analysis of cannabinoid receptor binding and mRNA expression and endogenous cannabinoid contents in the developing rat brain...

receptor and heightens the receptor's activity; the receptor antagonists work by binding to the receptor and blocking the activation of the receptor by...

of other cannabinoids, like THC and CBD. The pharmacodynamics of CBG are complex. It is a relatively weak ligand of the cannabinoid receptors, where it...

to that of Δ9-THC, with central effects occurring by binding to cannabinoid receptors found in various regions of the brain. Partial synthesis of ∆8-THC...

evolutionary history of 500 million years. The binding of cannabinoids to cannabinoid receptors decrease adenylyl cyclase activity, inhibit calcium N channels...

(December 2020). "Synthesis and in Vitro Cannabinoid Receptor 1 Activity of Recently Detected Synthetic Cannabinoids 4F-MDMB-BICA, 5F-MPP-PICA, MMB-4en-PICA...

To exert the psychoactive effect, specific receptors such as cannabinoid, dopamine and serotonin receptors are either stimulated or inhibited There are...

total cannabinoids have been reported.[2] THCV is a cannabinoid receptor type 1 antagonist or, at higher doses, a CB1 receptor agonist and cannabinoid receptor...

extracts exert immuno-modulating effect, not mediated by the cannabinoid CB1 and CB2 receptor coupled pathways like THC. THCA was able to inhibit the tumor...

at least 113 cannabinoids; however, most of these "minor" cannabinoids are only produced in trace amounts. Besides THC, another cannabinoid produced in...

CB1 receptors, meaning that much higher doses of CBN are required in order to experience effects, such as mild sedation. It was the first cannabinoid to...

therapeutic qualities of cannabinoids. She has been vocal about popularizing the healing apoptotic effect of cannabinoids on cannabinoid receptor containing cancer...