Complement component 4 (C4), in humans, is a protein involved in the intricate complement system, originating from the human leukocyte antigen (HLA) system...
35 KB (4,189 words) - 16:19, 7 November 2023
Complement component 3, often simply called C3, is a protein of the immune system that is found primarily in the blood. It plays a central role in the...
13 KB (1,556 words) - 13:28, 23 September 2024
the Complement system and the Complement component 2 protein attaches to Complement system 4 resulting in an immune response. Complement component 2 protein...
16 KB (2,068 words) - 18:45, 14 January 2024
Complement component 5 is a protein that in humans is encoded by the C5 gene. Complement component 5 is involved in the complement system. It is cleaved...
9 KB (1,114 words) - 05:29, 8 January 2024
Complement component 1s (EC 3.4.21.42, C1 esterase, activated complement C1s, complement C overbar 1r, C1s) is a protein involved in the complement system...
10 KB (1,195 words) - 05:11, 25 December 2023
Complement component 4B (Chido blood group) is a kind of the Complement component 4 protein that in humans is encoded by the C4B gene. This gene encodes...
8 KB (1,049 words) - 07:55, 3 January 2024
cleavage of complement component C5 by protease C5-convertase into C5a and C5b fragments. C5b is important in late events of the complement cascade, an...
15 KB (1,654 words) - 09:16, 27 February 2024
Complement C1r subcomponent (EC 3.4.21.41, activated complement C1r, C overbar 1r esterase, C1r) is a protein involved in the complement system of the...
10 KB (1,273 words) - 20:03, 12 May 2024
Complement component 9 (C9) is a MACPF protein involved in the complement system, which is part of the innate immune system. Once activated, about 12-18...
7 KB (789 words) - 09:32, 27 February 2024
Complement component 6 is a protein that in humans is encoded by the C6 gene. Complement component 6 is a protein involved in the complement system. It...
7 KB (910 words) - 05:30, 8 January 2024
and differentiation. The C4 gene encodes the complement component 4, which is involved in the complement system and is an important part of the innate...
28 KB (3,370 words) - 15:59, 27 June 2024
component of fresh serum. Ehrlich, therefore, named this heat-labile component "complement", because it is something in the blood that "complements"...
41 KB (5,016 words) - 12:33, 9 September 2024
Complement 4 deficiency is a genetic condition affecting complement component 4. It can present with lupus-like symptoms. Parija (2009). Textbook of Microbiology...
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express complement receptors on their surface. All four complement receptors can bind to fragments of complement component 3 or complement component 4 coated...
6 KB (376 words) - 06:42, 5 March 2024
Deficiencies of the terminal complement components increases susceptibility to infections by Neisseria. The cause of complement deficiency is genetics (though...
15 KB (1,260 words) - 14:35, 21 August 2024
in particular complement component 4. The vascular deposition of these types of cryoglobulin-containing immune complexes and complement can cause a clinical...
28 KB (2,996 words) - 19:59, 20 July 2024
functioning of the immune system. Other blood proteins act as enzymes, complement components, protease inhibitors or kinin precursors. Contrary to popular belief...
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C4A (redirect from Complement 4A)
Complement C4-A is a kind of the Complement component 4 protein that in humans is encoded by the C4A gene. This gene encodes the acidic form of complement...
13 KB (1,679 words) - 18:30, 14 August 2023
classical complement pathway is one of three pathways which activate the complement system, which is part of the immune system. The classical complement pathway...
16 KB (1,877 words) - 03:44, 5 April 2024
proteins in the complement cascade are activated, including complement component 2 (C2), complement component 3 (C3), and complement component 4 (C4). When...
22 KB (2,252 words) - 16:51, 21 September 2024
C4b-binding protein (redirect from Complement c4b-binding protein)
C4b-binding protein (C4BP) is a protein complex involved in the complement system where it acts as inhibitor. C4BP has an octopus-like structure with a...
3 KB (341 words) - 13:39, 11 October 2022
cells, leading to cell lysis and death. The MAC is composed of the complement components C5b, C6, C7, C8 and several C9 molecules. A number of proteins participate...
9 KB (1,061 words) - 05:28, 8 January 2024
pruning. Genes in the Complement Component 4 (C4) locus of the major histocompatibility complex (MHC), which encode for complement factors, have also been...
23 KB (2,972 words) - 02:10, 7 June 2024
antigens (HLA) HLA-DR4 and DRB1/DQA1, copy-number variations of complement component 4, a variant IL-23R locus and with various other non-HLA genes. HLA-DRB1*0405...
16 KB (1,496 words) - 00:27, 9 November 2023
Complement factor B is a protein that in humans is encoded by the CFB gene. This gene encodes complement factor B, a component of the alternative pathway...
9 KB (1,095 words) - 07:56, 3 January 2024
visual cortex critical period. More recently, the expression of the complement component 4 gene has been found to significantly contribute to abnormally high...
69 KB (8,677 words) - 16:30, 5 August 2024
(February 2016). "Schizophrenia risk from complex variation of complement component 4". Nature. 530 (7589): 177–183. Bibcode:2016Natur.530..177.. doi:10...
69 KB (7,347 words) - 10:58, 17 September 2024
Factor D (redirect from Complement factor d)
Factor D (EC 3.4.21.46, C3 proactivator convertase, properdin factor D esterase, factor D (complement), complement factor D, CFD, adipsin) is a protein...
18 KB (2,047 words) - 23:18, 16 August 2023
component of complement associated with anaphylactoid purpura and presence of mycoplasma in the serum". Clinical and Experimental Immunology. 14 (4)...
11 KB (929 words) - 15:36, 5 December 2023