• Complement component 4 (C4), in humans, is a protein involved in the intricate complement system, originating from the human leukocyte antigen (HLA) system...
    35 KB (4,189 words) - 16:19, 7 November 2023
  • Thumbnail for Complement component 3
    Complement component 3, often simply called C3, is a protein of the immune system that is found primarily in the blood. It plays a central role in the...
    15 KB (1,758 words) - 16:58, 16 July 2025
  • Thumbnail for Complement component 5
    Complement component 5 is a protein that in humans is encoded by the C5 gene. Complement component 5 is involved in the complement system. It is cleaved...
    9 KB (1,114 words) - 04:01, 15 July 2025
  • Thumbnail for Complement component 5a
    cleavage of complement component C5 by protease C5-convertase into C5a and C5b fragments. C5b is important in late events of the complement cascade, an...
    15 KB (1,654 words) - 09:16, 27 February 2024
  • Thumbnail for Complement component 4B
    Complement component 4B (Chido blood group) is a kind of the Complement component 4 protein that in humans is encoded by the C4B gene. This gene encodes...
    8 KB (1,049 words) - 07:55, 3 January 2024
  • Thumbnail for Complement component 9
    Complement component 9 (C9) is a MACPF protein involved in the complement system, which is part of the innate immune system. Once activated, about 12-18...
    7 KB (789 words) - 20:10, 20 January 2025
  • Thumbnail for Complement component 2
    the Complement system and the Complement component 2 protein attaches to Complement system 4 resulting in an immune response. Complement component 2 protein...
    16 KB (2,068 words) - 16:58, 16 July 2025
  • Thumbnail for Lupus
    Complement component 1qA, Complement component 1qB, Complement component 1r, Complement component 1s, Complement component 2, Complement component 3...
    139 KB (15,065 words) - 22:02, 5 July 2025
  • Thumbnail for Complement component 1r
    Complement C1r subcomponent (EC 3.4.21.41, activated complement C1r, C overbar 1r esterase, C1r) is a protein involved in the complement system of the...
    10 KB (1,273 words) - 20:03, 12 May 2024
  • Thumbnail for Complement component 1s
    Complement component 1s (EC 3.4.21.42, C1 esterase, activated complement C1s, complement C overbar 1r, C1s) is a protein involved in the complement system...
    10 KB (1,195 words) - 16:58, 16 July 2025
  • express complement receptors on their surface. All four complement receptors can bind to fragments of complement component 3 or complement component 4 coated...
    6 KB (380 words) - 11:15, 10 July 2025
  • Thumbnail for Complement deficiency
    Deficiencies of the terminal complement components increases susceptibility to infections by Neisseria. The cause of complement deficiency is genetics (though...
    15 KB (1,248 words) - 18:12, 28 January 2025
  • Thumbnail for Complement component 6
    Complement component 6 is a protein that in humans is encoded by the C6 gene. Complement component 6 is a protein involved in the complement system. It...
    7 KB (910 words) - 04:01, 15 July 2025
  • Thumbnail for Complement system
    component of fresh serum. Ehrlich, therefore, named this heat-labile component "complement," because it is something in the blood that "complements"...
    43 KB (5,123 words) - 16:58, 16 July 2025
  • C4 (redirect from C-4)
    column C04, oral cancer ICD-10 code Complement component 4, a protein involved in the intricate complement system, encoded by C4A or C4B gene in humans...
    7 KB (994 words) - 10:31, 7 March 2025
  • Thumbnail for C4A
    C4A (redirect from Complement 4A)
    Complement C4-A is a kind of the Complement component 4 protein that in humans is encoded by the C4A gene. This gene encodes the acidic form of complement...
    13 KB (1,679 words) - 21:56, 11 June 2025
  • Thumbnail for Cryoglobulinemia
    are abnormal proteins composed of immunoglobulins and sometimes complement components. Cryoglobulins specifically form gel-like solids by clumping together...
    35 KB (3,614 words) - 20:07, 6 July 2025
  • functioning of the immune system. Other blood proteins act as enzymes, complement, components, protease inhibitors or kinin precursors. Contrary to popular belief...
    6 KB (564 words) - 22:16, 23 May 2025
  • Thumbnail for Vogt–Koyanagi–Harada disease
    antigens (HLA) HLA-DR4 and DRB1/DQA1, copy-number variations of complement component 4, a variant IL-23R locus and with various other non-HLA genes. HLA-DRB1*0405...
    16 KB (1,498 words) - 15:17, 24 June 2025
  • Complement component 1qA, Complement component 1qB, Complement component 1r, Complement component 1s, Complement component 2, Complement component 3...
    84 KB (10,378 words) - 16:19, 9 June 2025
  • Complement 4 deficiency is a genetic condition affecting complement component 4. It can present with lupus-like symptoms. Parija (2009). Textbook of Microbiology...
    2 KB (81 words) - 04:09, 31 December 2019
  • Thumbnail for Synaptic pruning
    pruning. Genes in the Complement Component 4 (C4) locus of the major histocompatibility complex (MHC), which encode for complement factors, have also been...
    24 KB (3,156 words) - 17:26, 14 June 2025
  • Thumbnail for C4b-binding protein
    C4b-binding protein (C4BP) is a protein complex involved in the complement system where it acts as inhibitor. C4BP has an octopus-like structure with a...
    3 KB (341 words) - 00:55, 15 July 2025
  • visual cortex critical period. More recently, the expression of the complement component 4 gene has been found to significantly contribute to abnormally high...
    69 KB (8,689 words) - 05:00, 25 May 2025
  • Mycobacterium tuberculosis is mediated by human monocyte complement receptors and complement component C3". J. Immunol. 144 (7): 2771–80. doi:10.4049/jimmunol...
    9 KB (1,147 words) - 01:46, 25 November 2024
  • (February 2016). "Schizophrenia risk from complex variation of complement component 4". Nature. 530 (7589): 177–183. Bibcode:2016Natur.530..177.. doi:10...
    70 KB (7,425 words) - 06:06, 2 June 2025
  • Thumbnail for Structural variation in the human genome
    This study found that the association is caused partly by the complement component 4 (C4) genes and therefore implying that allele variants of the C4...
    29 KB (3,756 words) - 15:12, 9 June 2025
  • and differentiation. The C4 gene encodes the complement component 4, which is involved in the complement system and is an important part of the innate...
    28 KB (3,370 words) - 05:58, 2 June 2025
  • Thumbnail for Complex traits
    (February 2016). "Schizophrenia risk from complex variation of complement component 4". Nature. 530 (7589): 177–83. Bibcode:2016Natur.530..177.. doi:10...
    27 KB (2,719 words) - 06:51, 25 June 2025
  • Thumbnail for Complement membrane attack complex
    cells, leading to cell lysis and death. The MAC is composed of the complement components C5b, C6, C7, C8 and several C9 molecules. A number of proteins participate...
    9 KB (1,147 words) - 08:12, 30 December 2024