• dendritic cell-based cancer vaccine is an innovation in therapeutic strategy for cancer patients. Dendritic cells (DCs) are antigen presenting cells for...
    14 KB (1,616 words) - 21:16, 29 August 2023
  • melanoma cell lines, failed phase III clinical trials. Another cell-based vaccine strategy involves autologous dendritic cells (dendritic cells derived...
    27 KB (3,133 words) - 15:22, 26 April 2024
  • Thumbnail for Cancer immunotherapy
    PMID 11481463. Palucka K, Banchereau J (July 2013). "Dendritic-cell-based therapeutic cancer vaccines". Immunity. 39 (1): 38–48. doi:10.1016/j.immuni.2013...
    90 KB (9,943 words) - 09:46, 14 May 2024
  • Thumbnail for Cancer immunology
    Cancer vaccine Vaccine can be composed of killed tumor cells, recombinant tumor antigens, or dendritic cells incubated with tumor antigens (dendritic...
    33 KB (3,766 words) - 02:41, 25 April 2024
  • Thumbnail for Dendritic cell
    A dendritic cell (DC) is an antigen-presenting cell (also known as an accessory cell) of the mammalian immune system. A DC's main function is to process...
    34 KB (3,972 words) - 19:54, 25 May 2024
  • Thumbnail for MRNA vaccine
    Thielemans K, Breckpot K (February 2015). "mRNA-based dendritic cell vaccines". Expert Review of Vaccines. 14 (2): 161–76. doi:10.1586/14760584.2014.957684...
    78 KB (7,926 words) - 15:19, 26 April 2024
  • forms of cancer. Cell-based immunotherapies are effective for some cancers. Immune effector cells such as lymphocytes, macrophages, dendritic cells, natural...
    57 KB (5,884 words) - 06:16, 19 May 2024
  • Thumbnail for DNA vaccine
    A DNA vaccine is a type of vaccine that transfects a specific antigen-coding DNA sequence into the cells of an organism as a mechanism to induce an immune...
    77 KB (8,381 words) - 08:06, 22 February 2024
  • Thumbnail for Vaccine
    manufacture. Many innovative vaccines are also in development and use. Dendritic cell vaccines combine dendritic cells with antigens to present the antigens...
    140 KB (14,465 words) - 02:32, 24 May 2024
  • antigen-specific T-cell responses. Whole-cell vaccines have been researched in the fields of bacterial infectious disease (as an inactivated vaccine) and cancer (as...
    17 KB (1,961 words) - 03:04, 4 January 2024
  • Kiessling R (June 2012). "Myeloid-derived suppressor cells impair the quality of dendritic cell vaccines". Cancer Immunology, Immunotherapy. 61 (6): 827–838. doi:10...
    22 KB (2,634 words) - 05:02, 29 April 2024
  • experimental autologous dendritic cell COVID‑19 vaccine kit where the vaccine is prepared and incubated at the point-of-care using cells from the intended recipient...
    192 KB (22,024 words) - 20:15, 21 May 2024
  • Sipuleucel-T, a dendritic cell based vaccine for prostate cancer. Bacillus Calmettle-Guerin (TheraCys) is a live attenuated vaccine which makes use of...
    8 KB (1,116 words) - 00:50, 4 January 2024
  • |journal= (help) Cancer Research UK (2020-11-10). "A Cancer Research UK Phase I Trial of AST-VAC2 (Allogeneic Dendritic Cell Vaccine) Administered Weekly...
    19 KB (1,770 words) - 01:31, 8 April 2023
  • Drive the Growth of Colitis-Associated Colorectal Cancer by Controlling IL6 in Dendritic Cells". Cancer Immunology Research. 6 (9): 1082–1092. doi:10.1158/2326-6066...
    80 KB (9,560 words) - 05:24, 25 March 2024
  • vaccine can be made from dissembled viral particles in cell culture or recombinant DNA expression, in which case it is a recombinant subunit vaccine....
    67 KB (6,747 words) - 00:37, 12 April 2024
  • Thumbnail for Glioma
    IDH inhibitors like Ivosidenib, to the recently approved Dendritic cell-based cancer vaccine approach. Treatment using immunotherapy is another promising...
    57 KB (6,374 words) - 04:21, 29 April 2024
  • Cancer vaccine targeting CD4+ T cells is a type of vaccine used to treat existing cancer. Cancerous cells usually cannot be recognized by the human immune...
    10 KB (1,518 words) - 08:57, 5 May 2024
  • Thumbnail for T helper cell
    immune cells by releasing cytokines. They are considered essential in B cell antibody class switching, breaking cross-tolerance in dendritic cells, in the...
    54 KB (6,597 words) - 05:28, 15 May 2024
  • Thumbnail for Viral vector vaccine
    vector vaccine is a vaccine that uses a viral vector to deliver genetic material (DNA) that can be transcribed by the recipient's host cells as mRNA...
    32 KB (3,317 words) - 14:21, 24 January 2024
  • population, followed by monocytes, and only a small percentage of dendritic cells. These cells can be extracted from whole blood using ficoll, a hydrophilic...
    5 KB (541 words) - 07:23, 25 April 2024
  • PMID 11099314. Avigan D, Rosenblatt J, Kufe D (June 2012). "Dendritic/tumor fusion cells as cancer vaccines". Seminars in Oncology. 39 (3): 287–95. doi:10.1053/j...
    11 KB (1,383 words) - 07:24, 29 April 2024
  • Thumbnail for DC-SIGN
    recognition of tumors by dendritic cells. DC-SIGN is also a potential engineering target for dendritic cell based cancer vaccine. This molecule is involved...
    16 KB (2,089 words) - 07:32, 29 April 2024
  • Thumbnail for Cancer treatment
    malignant melanoma and renal cell carcinoma. Sipuleucel-T is a vaccine-like strategy for prostate cancer in which dendritic cells from the patient are loaded...
    70 KB (8,478 words) - 22:07, 22 May 2024
  • Thumbnail for Uğur Şahin
    BioNTech, which developed one of the major vaccines against COVID-19. His main fields of research are cancer research and immunology. Şahin's family, originally...
    56 KB (6,116 words) - 05:50, 18 May 2024
  • Thumbnail for Murine respirovirus
    Recent applications of SeV-based vectors include the reprogramming of somatic cells into induced pluripotent stem cells and vaccine creation. For vaccination...
    281 KB (30,419 words) - 20:08, 25 May 2024
  • Thumbnail for Viral vector
    were viral vector-based. Further, compared to traditional vaccines, the intracellular antigen expression enabled by viral vector vaccines offers more robust...
    48 KB (5,482 words) - 22:04, 24 May 2024
  • conjunction with the vaccine can greatly increase the innate immune response to the antigen by augmenting the activities of dendritic cells, lymphocytes, and...
    37 KB (4,220 words) - 10:13, 27 March 2024
  • for chemotherapy of cancer 2010  – US FDA approves immunotherapy, sipuleucel-T dendritic cell vaccine for advanced prostate cancer 2010  – China advances...
    27 KB (2,580 words) - 18:15, 7 September 2023
  • shown the safety and efficacy of delivering mature, peptide-pulsed dendritic cell vaccines in a variety of ways. His research also has discovered alternate...
    6 KB (610 words) - 00:22, 2 May 2023