Folate, also known as vitamin B9 and folacin, is one of the B vitamins. Manufactured folic acid, which is converted into folate by the body, is used as...

Folate deficiency, also known as vitamin B9 deficiency, is a low level of folate and derivatives in the body. This may result in megaloblastic anemia in...

blood donation. Causes of decreased production include iron deficiency, folate deficiency, vitamin B12 deficiency, thalassemia and a number of bone marrow...

vitamin, folate (folic acid), to a molecule/drug to form a "folate conjugate". Based on the natural high affinity of folate for the folate receptor protein...

by name than by number, such as pantothenic acid (B5), biotin (B7), and folate (B9). B vitamins are present in protein-rich foods, such as fish, poultry...

Reduced Folate Carrier (RFC) Family (TC# 2.A.48) is a group of transport proteins that is part of the major facilitator superfamily. RFCs take up folate, reduced...

4% chance that the next child will also be affected. Not having enough folate (vitamin B9) in the diet before and during pregnancy also plays a significant...

which has decreased from around 5 per 10,000 (0.05% of US births) since folate fortification of grain products was started. The number of deaths in the...

Hereditary folate malabsorption (HFM) is a rare autosomal recessive disorder caused by loss-of-function mutations in the proton-coupled folate transporter...

such as proguanil, pyrimethamine and trimethoprim selectively inhibit folate's actions in microbial organisms such as bacteria, protozoa and fungi. The...

Cerebral folate deficiency is a condition in which concentrations of 5-methyltetrahydrofolate are low in the brain as measured in the cerebral spinal fluid...

skin pigmentation was the breakdown of folate in reaction to ultraviolet radiation; the relationship between folate breakdown induced by ultraviolet radiation...

Folate receptors bind folate and reduced folic acid derivatives and mediates delivery of tetrahydrofolate to the interior of cells. It is then converted...

spinal cord strongly suggests the presence of a B12 deficiency instead of folate deficiency. Methylmalonic acid, if not properly handled by B12, remains...

Folate receptor 1 (Folate receptor alpha, FOLR1) is a protein that in humans is encoded by the FOLR1 gene. The protein encoded by this gene is a member...

Prostate cancer is the uncontrolled growth of cells in the prostate, a gland in the male reproductive system below the bladder. Abnormal growth of the...

(6S)-5-methyltetrahydrofolate, and (6S)-5-MTHF) is the primary biologically active form of folate used at the cellular level for DNA reproduction, the cysteine cycle and...

Folate transporter 1 is a protein which in humans is encoded by the SLC19A1 gene. Transport of folate compounds into mammalian cells can occur via receptor-mediated...

intermediate interferes with the normal bacterial synthesis of folic acid (folate). Folate is an essential metabolite for bacterial growth and replication because...

causes from an anemia of a single cause. Deficiencies of Vitamin B12 or folate produce a macrocytic anemia (large cell anemia) in which the RDW is elevated...

known as folate receptor 4, folate receptor delta or IZUMO1R is a protein that in humans is encoded by the FOLR4 gene. Juno is a member of the folate receptor...

most often due to hypovitaminosis, specifically vitamin B12 deficiency or folate deficiency. Loss of micronutrients may also be a cause. Megaloblastic anemia...

The proton-coupled folate transporter is a protein that in humans is encoded by the SLC46A1 gene. The major physiological roles of PCFTs are in mediating...

1186/s12976-016-0037-2 Björklund, NK, Gordon, R A hypothesis linking low folate intake to neural tube defects due to failure of post-translation methylations...

Folate-binding protein (FBP) are proteins that bind folate, typically the folate receptors and reduced folate carrier. FBP can be a marker for ovarian...

concentration, as vitamin C is degraded by heating. Folate levels may also be decreased, as folate tends to leach into cooking liquid. Spinach is rich...

membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene. Human GCPII contains 750 amino acids and weighs approximately...

The folate-biopterin transporter (FBT) family (TC# 2.A.71) is a distant family within the major facilitator superfamily, most closely related to drug resistance...

miscarriage, neural tube defects, and developmental delays in offspring. Folate levels may modify the presentation of symptoms and disease course. Vitamin...

naturally-occurring forms of folate, and which only contributes a minor amount to the folates occurring in natural foods. In many cases, such as with folate, it is an open...