A gene cluster is a group of two or more genes found within an organism's DNA that encode similar polypeptides or proteins which collectively share a generalized...
16 KB (1,917 words) - 13:57, 31 October 2024
anemones. This implies that Hox genes arose over 550 million years ago. In bilateria, Hox genes are often arranged in gene clusters, although there are many...
51 KB (6,109 words) - 09:55, 18 May 2025
Metabolic gene clusters or biosynthetic gene clusters are tightly linked sets of mostly non-homologous genes participating in a common, discrete metabolic...
10 KB (1,175 words) - 23:21, 24 May 2025
ParaHox (category Gene clusters)
The ParaHox gene cluster is an array of homeobox genes (involved in morphogenesis, the regulation of patterns of anatomical development) from the Gsx,...
5 KB (645 words) - 02:39, 2 May 2025
Teicoplanin (section Gene cluster)
gene clusters. The function of each of these genes is described by Li and co-workers. A summary of the gene layout and purpose is shown below. Gene layout...
28 KB (2,967 words) - 13:12, 7 June 2025
the 9-hydroxy-nonanoic acid portion of mupirocin. The 74 kb mupirocin gene cluster contains six multi-domain enzymes and twenty-six other peptides (Table...
30 KB (2,609 words) - 21:35, 29 May 2025
human genome, a cluster of thirteen functional IFN genes is located at the 9p21.3 cytoband over approximately 400 kb including coding genes for IFNα (IFNA1...
24 KB (2,934 words) - 22:15, 24 May 2025
CRT is the gene cluster responsible for the biosynthesis of carotenoids. Those genes are found in eubacteria, in algae and are cryptic in Streptomyces...
14 KB (1,384 words) - 03:37, 27 May 2025
Machine learning in bioinformatics (section Clustering and abundance profiling of biosynthetic gene clusters)
this algorithm has been used both to cluster biosynthetic gene clusters in gene cluster families(GCF) and to cluster said GCFs. Typically, a workflow for...
72 KB (8,279 words) - 02:49, 26 May 2025
Ciclosporin (section Gene cluster)
production of Cyclosporin, has the biosynthetic genes arranged into a 12-gene cluster. Of these 12 genes, SimA (Q09164) is the cyclosporin synthetase, SimB...
58 KB (5,376 words) - 15:25, 1 June 2025
MHC class III (category Genes on human chromosome 6)
from their genes because their gene cluster is present between those of class I and class II. The gene cluster was discovered when genes (specifically...
6 KB (745 words) - 04:06, 27 May 2025
deleted, and expression of the cluster of structural genes is under the control of cellular regulatory systems. Additional genes that contribute to GTA production...
23 KB (2,692 words) - 07:51, 25 May 2025
prognosis. The gene cluster for biosynthesis of avermectin from S. avermitilis has been sequenced. The avermectin biosynthesis gene cluster encodes enzymes...
17 KB (1,838 words) - 05:14, 30 May 2025
Homeobox (redirect from HOX cluster)
arrangement in the genome. Hox genes are typically found in an organized cluster. The linear order of Hox genes within a cluster is directly correlated to...
41 KB (4,386 words) - 22:42, 24 May 2025
Winter cluster, in beekeeping, a well-defined cluster of honey bees in cold temperatures Disease cluster, a grouping of cases of disease Gene cluster, a group...
5 KB (676 words) - 17:51, 3 September 2024
protein and is the first gene found in the clavulanic acid biosynthesis gene cluster, encoded by orf2 of the clavulanic acid gene cluster. The specific mechanism...
24 KB (2,144 words) - 22:32, 24 May 2025
acyltransferase (encoded as OxyA, OxyB, OxyC and OxyP in the oxytetracycline gene cluster) to catalyze the extension of the malonamyl-CoA starting unit with eight...
17 KB (1,709 words) - 08:52, 27 May 2025
Plasmid (category Gene delivery)
a pre-built database—tools to do this include mge-cluster. As plasmid frequently change their gene content and order, modelling genetic distances between...
73 KB (8,310 words) - 05:49, 9 June 2025
analysis indicated the presence of at least four gene clusters involved in secondary metabolism. Two gene clusters are related to the production of aryl polyenes...
12 KB (1,329 words) - 12:09, 26 March 2025
oryzae. While the two fungi share the same cluster of genes that encode for aflatoxin synthesis, this gene cluster is non-functional in A. oryzae. Eiji Ichishima...
29 KB (2,877 words) - 05:04, 16 May 2025
D, Horsthemke B, Buiting K (2005). "Exclusion of the C/D box snoRNA gene cluster HBII-52 from a major role in Prader-Willi syndrome". Hum Genet. 116 (3):...
40 KB (4,174 words) - 11:45, 24 May 2025
Mucin (section Genes and proteins)
Willebrand Factor (PTHR11339). Four of these occur in a well-conserved gene cluster (at 11p.15.5 in humans). The EGF-like domain containing mucins. These...
22 KB (2,344 words) - 00:32, 24 May 2025
Tandemly arrayed genes (TAGs) are a gene cluster created by tandem duplications, a process in which one gene is duplicated and the copy is found adjacent...
4 KB (422 words) - 16:08, 21 August 2024
Brigitte; Guilhot, Christophe (1999-10-01). "Identification of a virulence gene cluster of Mycobacterium tuberculosis by signature-tagged transposon mutagenesis"...
18 KB (2,213 words) - 01:59, 1 December 2023
Blasticidin S (section Resistance genes)
gene cluster via heterologous reconstitution of Blasticidin S production in Streptomyces lividans, indicated that a 20 Kbp gene cluster with 19 genes...
7 KB (580 words) - 19:06, 1 July 2024
of carbohydrate-active enzymes and secondary metabolite biosynthetic gene clusters (siderophores, e-Polylysin and type III lanthipeptides) that are related...
38 KB (3,756 words) - 05:28, 2 June 2025
biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase". Gene. 169 (1):...
75 KB (7,492 words) - 05:38, 9 June 2025
NRPS genes from three different sites in the chromosome, using ermEp* for expression of two genes from ectopic loci; other lipopeptide gene clusters, both...
38 KB (3,787 words) - 20:32, 29 May 2025
cases, each cluster is made up of sequences produced by a single gene, including alternatively spliced transcripts. However, some genes may be represented...
9 KB (1,265 words) - 18:48, 11 September 2022
similarity networks of biosynthetic gene clusters (BGC). In successive layers of clusterization of biosynthetic gene clusters are used in the automated tool...
14 KB (1,992 words) - 22:54, 9 March 2025