Hyper IgM syndrome is a rare primary immune deficiency disorders characterized by low or absent levels of serum IgG, IgA, IgE and normal or increased levels...

syndrome Hurler–Scheie syndrome Hutchinson–Gilford progeria syndrome Hydrolethalus syndrome Hyper IgM syndrome Hyper-IgD syndrome Hyper-IgM syndrome type...

Hyper IgM syndrome type 1 (HIGM-1) is the X-linked variant of the hyper IgM syndrome. The affected individuals are virtually always male, because males...

Hyper-IgM syndrome type 3 is a form of hyper IgM syndrome characterized by mutations of the CD40 gene. In this type, Immature B cells cannot receive signal...

Hyper IgM syndrome type 2 is a rare disease. Unlike other hyper-IgM syndromes, type 2 patients identified thus far did not present with a history of opportunistic...

Hyper-IgM syndrome is a primary immunodeficiency disorder characterized by increased serum levels of immunoglobulin (Ig) M and decreased levels of IgG...

Hyper-IgM syndrome type 4 is a form of Hyper IgM syndrome which is a defect in class switch recombination downstream of the AICDA gene that does not impair...

fifth type of hyper-IgM syndrome has been characterized in three patients from France and Japan. The symptoms are similar to hyper IgM syndrome type 2, but...

autosomal recessive. Many patients with autosomal dominant STAT3 hyper-IgE syndrome have characteristic facial and dental abnormalities, fail to lose...

Infections with Pneumocystis pneumonia are also common in infants with hyper IgM syndrome, an X-linked or autosomal recessive trait. The causative organism...

cytokine B cell signalling. Defects in this gene are associated with Hyper-IgM syndrome type 2. In certain haematological malignancies such as follicular...

immunoglobulins, which are IgA, IgE and IgG. There are 5 types of hypergammaglobulinemias associated with hyper IgM. MeSH considers hyper IgM syndrome to be a form...

IgD.: 84  Immunoglobulin M deficiency Immunoglobulin M Skin lesion List of cutaneous conditions "X-linked hyper-IgM syndrome". Orphanet. Retrieved 18...

bacteria and fungi. Wiskott–Aldrich syndrome (WAS) Autoimmune lymphoproliferative syndrome (ALPS) Hyper IgM syndrome: X-linked disorder that causes a deficiency...

to undergo immunoglobulin class switching and is associated with hyper IgM syndrome. Absence of CD154 also stops the formation of germinal centers and...

syndromes such as hyper-IgM syndrome or SCID, which have an estimated incidence of about one in 1,000,000 live births, and Wiskott–Aldrich syndrome is...

deficiency. Normal numbers of B cells with decreased IgG and IgA and increased IgM: Hyper-IgM syndromes Normal numbers of B cells with isotype or light chain...

in the gene encoding mevalonate kinase cause hyper-IgD and periodic fever syndrome. International Hyper-IgD Study Group". Nat. Genet. 22 (2): 178–81. doi:10...

of an immune deficiency, such as X-linked agammaglobulinemia and hyper IgM syndrome. Such injections are less common in modern medical practice than they...

Wiskott–Aldrich syndrome, Hyper IgM syndrome, X-linked agammaglobulinemia, IPEX syndrome and autosomal dominante Hyper IgE syndrome. To improve the long-term...

deficiency, Hyper IgM syndrome Barth syndrome Copper deficiency Vitamin B12 deficiency Pearson syndrome Some types of Hermansky–Pudlak syndrome Transient...

Hydroxymethylglutaric aciduria Hygroma cervical Hymenolepiasis Hyper IgE Hyper IgM syndrome Hyperadrenalism Hyperaldosteronism familial type 2 Hyperaldosteronism...

the spleen are the main source of specific IgM production. In 1937, an antibody was observed in horses hyper-immunized with pneumococcus polysaccharide...

lymphocytes Fred Rosen (1930-2005), discovered the cause of X-linked hyper IgM syndrome Christopher E. Rudd (1963-), discovery of T-cell activation mechanisms...

IgM. IgG subclass deficiencies are also an integral component of other well-known primary immunodeficiency diseases, such as Wiskott–Aldrich syndrome...

(ARA), common variable immunodeficiency (CVID), hyper-IgM syndromes, IgG subclass deficiency, isolated non-IgG immunoglobulin deficiencies, severe combined...

Immunodeficiency with hyper-IgM Immunodeficiency–centromeric instability–facial anomalies syndrome (ICF syndrome) Isolated IgA deficiency Isolated primary IgM deficiency...

deficiency. Normal numbers of B cells with decreased IgG and IgA and increased IgM: Hyper-IgM syndromes Normal numbers of B cells with isotype or light chain...

infections and low antibody levels, specifically in immunoglobulin (Ig) types IgG, IgM, and IgA. Symptoms generally include high susceptibility to pathogens...

inherited form of diabetes CGMP-specific phosphodiesterase type 5 Hyper-IgM syndrome type 5 PDE5 inhibitor, a vasodilator drug Type 5 cannon, a Japanese...