Interleukin-23 subunit alpha is a protein that in humans is encoded by the IL23A gene. The protein is also known as IL-23p19. It is one of the two subunits...
13 KB (1,583 words) - 00:31, 15 January 2025
Interleukin 23 (IL-23) is a heterodimeric cytokine composed of an IL-12B (IL-12p40) subunit (which is shared with IL-12) and an IL-23A (IL-23p19) subunit...
20 KB (2,189 words) - 13:46, 19 January 2025
Interleukin-1 alpha (IL-1 alpha) also known as hematopoietin 1 is a cytokine of the interleukin 1 family that in humans is encoded by the IL1A gene. In...
22 KB (2,685 words) - 12:41, 2 April 2025
heterodimer with a unique alpha chain paired with the common beta (beta c or CD131) subunit. The gene for the alpha subunit is 40 kilobases long and has...
2 KB (206 words) - 15:30, 8 September 2024
p40, or interleukin-12 subunit p40) is a protein subunit that in humans is encoded by the IL12B gene. IL-12B is a common subunit of interleukin 12 and...
10 KB (1,383 words) - 03:56, 13 August 2023
shown to interact with interleukin 5 receptor alpha subunit. The IL-5 receptor is composed of an α and a βc chain. The α subunit is specific for the IL-5...
13 KB (1,529 words) - 06:56, 4 March 2025
Interleukin 15 receptor, alpha subunit is a subunit of the interleukin 15 receptor that in humans is encoded by the IL15RA gene. The IL-15 receptor is...
9 KB (1,235 words) - 03:38, 24 December 2023
Interleukin 27 receptor, alpha is a subunit of the interleukin-27 receptor. IL27RA is its human gene. In mice, CD4+ helper T-cells differentiate into type...
5 KB (668 words) - 22:10, 29 September 2022
Interleukin 20 receptor, alpha subunit, is a subunit of the interleukin-20 receptor, the interleukin-26 receptor, and the interleukin-24 receptor. The...
11 KB (1,248 words) - 18:24, 21 May 2025
effects of interleukin 11. Interleukin 12 (IL-12) is a disulphide-bonded heterodimer consisting of a 35kDa alpha subunit and a 40kDa beta subunit. It is involved...
45 KB (4,194 words) - 12:36, 2 May 2024
Interleukin-7 receptor subunit alpha (IL7R-α) also known as CD127 (Cluster of Differentiation 127) is a protein that in humans is encoded by the IL7R gene...
6 KB (840 words) - 23:23, 20 February 2024
Interleukin 11 receptor, alpha subunit is a subunit of the interleukin 11 receptor. IL11RA is its human gene. Interleukin 11 is a stromal cell-derived...
8 KB (1,034 words) - 09:00, 2 November 2024
Interleukin 28 receptor, alpha subunit is a subunit for the interleukin-28 receptor. IL28RA is its human gene. The protein encoded by this gene belongs...
1 KB (169 words) - 02:07, 8 April 2022
IL2RA (redirect from Interleukin-2 receptor alpha chain)
with interleukin-2, a pleiotropic cytokine which plays an important role in immune homeostasis. The human protein interleukin-2 receptor subunit alpha is encoded...
23 KB (2,605 words) - 13:06, 14 February 2025
Interleukin-10 receptor subunit alpha is a subunit for the interleukin-10 receptor. IL10RA is its human gene. IL10RA has also been designated CDw210a (cluster...
11 KB (1,334 words) - 00:45, 3 October 2024
The interleukin 4 receptor is a type I cytokine receptor. It is a heterodimer, that is, composed of two subunits. IL4R is the human gene coding for IL-4Rα...
7 KB (781 words) - 08:35, 20 August 2024
to the family of interleukin-12. IL-12 family is unique in comprising the only heterodimeric cytokines, which includes IL-12, IL-23, IL-27 and IL-35....
14 KB (1,578 words) - 15:30, 24 January 2025
Interleukin 12 receptor, beta 2 subunit is a subunit of the interleukin 12 receptor. IL12RB2 is its human gene. IL12RB2 orthologs have been identified...
9 KB (1,197 words) - 04:28, 1 January 2024
Interleukin 5 receptor, alpha (IL5RA) also known as CD125 (Cluster of Differentiation 125) is a subunit of the Interleukin-5 receptor. IL5RA also denotes...
12 KB (1,569 words) - 05:04, 1 January 2024
The interleukin-5 receptor is a type I cytokine receptor. It is a heterodimer of the interleukin 5 receptor alpha subunit and CSF2RB. The IL-5 receptor...
7 KB (848 words) - 17:57, 13 March 2025
complex with the interleukin-12 receptor β1 subunit (IL-12Rβ1), it is activated by the cytokine interleukin 23 (IL-23). The IL23R mRNA is 2.8 kilobases in length...
13 KB (1,589 words) - 02:42, 19 December 2023
multi-subunit receptor with IL-4. This receptor is a heterodimer receptor complex consisting of alpha IL-4 receptor (IL-4Rα) and alpha Interleukin-13 receptor...
23 KB (2,996 words) - 13:46, 29 March 2025
protein chains - i.e. it is a heterodimer, and consists of two subunits, interleukin-7 receptor-α (CD127) and common-γ chain receptor (CD132). The common-γ...
6 KB (550 words) - 00:43, 19 August 2023
Interleukin-12 receptor, beta 1, or IL-12Rβ1 in short, is a subunit of the interleukin 12 receptor and the interleukin 23 receptor. IL12RB1, is the name...
11 KB (1,323 words) - 16:26, 21 August 2024
two genes for interleukin-1 (IL-1): IL-1 alpha and IL-1 beta (this gene). IL-1β precursor is cleaved by cytosolic caspase 1 (interleukin 1 beta convertase)...
26 KB (3,273 words) - 08:48, 14 October 2024
chains, termed alpha (CD25), beta (CD122) and gamma (CD132). The gamma chain is common to all family members. The IL-2 receptor (IL-2R) α subunit binds IL-2...
43 KB (5,007 words) - 10:38, 22 December 2024
The interleukin 11 receptor is a type I cytokine receptor, binding interleukin 11. It is a heterodimer composed of an interleukin 11 receptor alpha subunit...
2 KB (96 words) - 09:00, 2 November 2024
been reported. IL6R subunit is also shared by many other cytokines. Interleukin-6 receptor has been shown to interact with Interleukin 6 and ciliary neurotrophic...
11 KB (1,446 words) - 18:05, 6 March 2025
association of atopy with a gain-of-function mutation in the alpha subunit of the interleukin-4 receptor". The New England Journal of Medicine. 337 (24):...
19 KB (2,297 words) - 19:50, 8 March 2025
Interleukin-15 (IL-15) is a protein that in humans is encoded by the IL15 gene. IL-15 is an inflammatory cytokine with structural similarity to Interleukin-2...
39 KB (4,458 words) - 06:59, 3 June 2024