Iron overload (also known as haemochromatosis or hemochromatosis) is the abnormal and increased accumulation of total iron in the body, leading to organ...
46 KB (4,697 words) - 16:27, 24 March 2025
understanding diseases of iron overload, such as hereditary hemochromatosis, and iron deficiency, such as iron-deficiency anemia. Iron is an essential bioelement...
46 KB (5,568 words) - 01:38, 30 April 2025
African iron overload is an iron overload disorder first observed among people of African descent in Southern Africa and Central Africa. It is now recognized...
21 KB (2,166 words) - 15:37, 17 November 2024
Hereditary haemochromatosis (category Iron metabolism)
primary storage area for iron and naturally accumulates excess iron over time, it is likely to be damaged by iron overload. Toxins may accumulate in...
69 KB (7,315 words) - 07:49, 9 May 2025
Transfusion hemosiderosis (redirect from Transfusional iron overload)
removes iron from the blood. This involves delivering iron chelating agents such as deferoxamine, deferiprone or deferasirox. If iron overload has caused...
7 KB (666 words) - 01:13, 25 February 2024
Ferritin (category Iron metabolism)
total amount of iron stored in the body; hence, serum ferritin is used as a diagnostic test for iron-deficiency anemia and iron overload. Aggregated ferritin...
46 KB (5,289 words) - 03:56, 9 February 2025
Chelation therapy (redirect from Iron-chelating drug)
Nurchi, Valeria M.; Lachowicz, Joanna (2019). "Chapter 3. Iron Chelation for Iron Overload in Thalassemia". In Sigel, Astrid; Freisinger, Eva; Sigel,...
45 KB (4,435 words) - 22:44, 24 February 2025
Myelodysplastic syndrome (section Iron levels)
secondary hemochromatosis due to iron overload from repeated transfusions. Patients with chronic iron overload can have iron deposits in their liver, heart...
62 KB (6,515 words) - 08:29, 17 May 2025
deletion also had increased duodenal iron absorption, elevated plasma iron and transferrin saturation levels, and iron overload, mainly in hepatocytes. Mice have...
19 KB (2,137 words) - 05:56, 27 September 2024
Hemosiderosis (category Iron metabolism)
Hemosiderosis is a form of iron overload disorder resulting in the accumulation of hemosiderin. Types include: Transfusion hemosiderosis Idiopathic pulmonary...
12 KB (1,300 words) - 06:26, 24 November 2024
Alpha-thalassemia (section Iron chelation)
and include anemia, pallor, tiredness, enlargement of the spleen, iron overload, abnormal bone structure, jaundice, and gallstones. In severe cases...
33 KB (4,411 words) - 08:38, 21 March 2025
Thalassemia (section Iron chelation)
transfusion in case of an anemia crisis. Complications of transfusion include iron overload with resulting heart or liver disease. Other symptoms of thalassemias...
75 KB (7,679 words) - 03:28, 23 April 2025
Transferrin saturation (redirect from Iron saturation)
saturation is a common indicator of iron deficiency anemia whereas a high transferrin saturation may indicate iron overload or hemochromatosis. Transferrin...
5 KB (590 words) - 14:28, 31 July 2023
Other side effects, which may occur with excessive use, include iron overload and iron toxicity. Ferrous salts used as supplements by mouth include ferrous...
42 KB (4,333 words) - 20:04, 28 April 2025
Stellenbosch University, where she conducted influential research into iron overload. She is now the managing director of Gene Diagnostics, a private genetic...
6 KB (436 words) - 20:13, 31 July 2024
chemotherapy may develop iron deficiency and anemia, for which intravenous iron therapy is used to restore iron levels. Iron overload, which may occur from...
149 KB (16,921 words) - 06:41, 17 April 2025
Beta thalassemia (section Iron chelation)
ineffective production of red blood cells, increased hemolysis, and iron overload. Diagnosis is by checking the medical history of near relatives, microscopic...
35 KB (6,224 words) - 14:27, 9 May 2025
dependence is iron overloading, which can damage the liver, heart, bone tissue and endocrine glands. Iron chelation therapy is used to treat iron overload and common...
25 KB (2,854 words) - 16:14, 19 November 2024
Hemochromatosis type 4 is a hereditary iron overload disorder that affects ferroportin, an iron transport protein needed to export iron from cells into circulation...
14 KB (1,716 words) - 14:58, 27 October 2023
iron fish, a small iron ingot used during cooking to provide dietary iron to those with iron deficiency. People with hemochromatosis (iron overload,...
18 KB (2,244 words) - 04:04, 15 April 2025
diabetic ketoacidosis, low white blood cells, cancer, organ transplant, iron overload, kidney problems, long-term steroids or use of immunosuppressants, and...
59 KB (5,648 words) - 00:48, 12 April 2025
Look up overload or overloaded in Wiktionary, the free dictionary. Overload or overloaded may refer to: Overload (novel), a 1979 novel by Arthur Hailey...
3 KB (433 words) - 20:34, 19 June 2024
brand name Exjade among others, is an oral iron chelator. Its main use is to reduce chronic iron overload in patients who are receiving long-term blood...
11 KB (756 words) - 00:08, 13 January 2025
transferrin saturation: markers of iron overload as in hemochromatosis, copper and ceruloplasmin: markers of copper overload as in Wilson's disease Immunoglobulin...
120 KB (12,524 words) - 09:35, 12 May 2025
Ferriprox among others, is a medication that chelates iron and is used to treat iron overload in thalassaemia major. It was first approved and indicated...
11 KB (889 words) - 08:57, 6 August 2024
accessing iron in the blood, which causes anemia that is apparent at birth. It can lead to pallor, fatigue, and slow growth. The iron overload aspect of...
14 KB (1,766 words) - 17:13, 27 August 2024
Hepcidin (category Iron metabolism)
serum iron being available for developing red blood cells. When the hepcidin level is abnormally low, such as in hemochromatosis, iron overload occurs...
24 KB (2,599 words) - 04:43, 24 December 2024
retardation, aminoaciduria (amino acids in the urine), cholestasis, iron overload, lactic acidosis and early death. Prior to birth, the growth of the...
6 KB (609 words) - 05:52, 2 November 2023
cases of iron overload. The ferritin storage iron pool is much larger than the labile iron pool, ranging in concentration from 0.7 mM to 3.6 mM. Iron export...
44 KB (5,350 words) - 14:05, 24 December 2024
Anemia (section Fluid overload)
dependence. Concerns from repeated blood transfusions include iron overload. This iron overload may require chelation therapy. The global market for anemia...
88 KB (9,069 words) - 12:24, 27 March 2025