• Thumbnail for Leukemia inhibitory factor
    Leukemia inhibitory factor, or LIF, is an interleukin 6 class cytokine that affects cell growth by inhibiting differentiation. When LIF levels drop, the...
    13 KB (1,583 words) - 04:50, 17 August 2024
  • Thumbnail for Leukemia inhibitory factor receptor
    Differentiation 118), is a subunit of a receptor for leukemia inhibitory factor. The leukemia inhibitory factor (LIF) is a polyfunctional cytokine that affects...
    11 KB (1,325 words) - 16:37, 6 April 2024
  • unknown. The CNTF family of neurotrophic factors includes ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), interleukin-6 (IL-6), prolactin...
    16 KB (1,784 words) - 04:08, 6 January 2024
  • Thumbnail for Implantation (embryology)
    there is no evidence to support their involvement in hatching. Leukemia inhibitory factor (LIF) is a pro-inflammatory cytokine expressed in the endometrium...
    51 KB (5,859 words) - 20:34, 3 March 2025
  • negative regulating factors are known (such as dopamine, leukemia inhibitory factor, some prostaglandins) but few stimulating factor. Its secretion is mediated...
    1 KB (181 words) - 14:07, 14 November 2022
  • motility factor Bone morphogenetic proteins (BMPs) Ciliary neurotrophic factor family Ciliary neurotrophic factor (CNTF) Leukemia inhibitory factor (LIF)...
    10 KB (1,131 words) - 18:45, 6 May 2025
  • Thumbnail for Serum (blood)
    growth factors and is frequently added to growth media used for eukaryotic cell culture. A combination of FBS and the cytokine leukemia inhibitory factor was...
    7 KB (736 words) - 11:54, 31 July 2024
  • album A Natural Death "Líf", a song by Hildur Vala Einarsdóttir Leukemia inhibitory factor, a cytokine that affects cell growth and development Laser-induced...
    1 KB (189 words) - 19:46, 4 May 2025
  • Thumbnail for Oncostatin M
    group of cytokines. Of these cytokines it most closely resembles leukemia inhibitory factor (LIF) in both structure and function. As yet poorly defined, it...
    32 KB (4,317 words) - 12:20, 2 November 2024
  • Thumbnail for Brain-derived neurotrophic factor
    Brain-derived neurotrophic factor (BDNF), or abrineurin, is a protein that, in humans, is encoded by the BDNF gene. BDNF is a member of the neurotrophin...
    50 KB (5,881 words) - 13:31, 5 May 2025
  • Colony-stimulating factors (CSFs) are secreted glycoproteins that bind to receptor proteins on the surfaces of committed progenitors in the bone marrow...
    3 KB (374 words) - 18:45, 17 July 2023
  • fibroblast growth factor receptors (FGFR) are, as their name implies, receptors that bind to members of the fibroblast growth factor (FGF) family of proteins...
    8 KB (827 words) - 14:53, 16 April 2025
  • Thumbnail for Fibroblast growth factor 2
    Fibroblast growth factor 2 (FGF-2), also known as basic fibroblast growth factor (bFGF) and FGF-β, is a growth factor and signaling protein encoded by...
    22 KB (2,698 words) - 15:56, 25 May 2025
  • Thumbnail for Stem cell factor
    Stem cell factor (also known as SCF, KIT-ligand, KL, or steel factor) is a cytokine that binds to the c-KIT receptor (CD117). SCF can exist both as a transmembrane...
    23 KB (2,958 words) - 06:49, 29 April 2025
  • Thumbnail for Axitinib
    (BCR-ABL1[T315I]) that is common in chronic myeloid leukemias and adult acute lymphoblastic leukemias which have become resistant to other tyrosine kinase...
    16 KB (1,239 words) - 20:04, 29 May 2025
  • Thumbnail for Promyelocytic leukemia protein
    Promyelocytic leukemia protein (PML) (also known as MYL, RNF71, PP8675 or TRIM19) is the protein product of the PML gene. PML protein is a tumor suppressor...
    33 KB (4,053 words) - 07:02, 10 July 2024
  • Thumbnail for Insulin-like growth factor 1
    Insulin-like growth factor 1 (IGF-1), also called somatomedin C, is a hormone similar in molecular structure to insulin which plays an important role in...
    34 KB (4,517 words) - 04:19, 9 June 2025
  • F, et al. (2003). "Vascular endothelial growth factor and its receptors in multiple myeloma". Leukemia. 17 (10): 1961–6. doi:10.1038/sj.leu.2403076. PMID 14513045...
    40 KB (4,578 words) - 12:30, 10 September 2024
  • Thumbnail for Hepatocyte growth factor
    Hepatocyte growth factor (HGF) or scatter factor (SF) is a paracrine cellular growth, motility and morphogenic factor. It is secreted by mesenchymal cells...
    23 KB (2,623 words) - 08:53, 15 March 2025
  • Thumbnail for Glycoprotein 130
    with gp130, such as cardiotrophin 1 (CT-1), leukemia inhibitory factor (LIF), ciliary neurotrophic factor (CNTF), oncostatin M (OSM), and IL-11. There...
    20 KB (2,477 words) - 01:52, 14 June 2025
  • Thumbnail for Vascular endothelial growth factor C
    endothelial growth factor C (VEGF-C) is a protein that is a member of the platelet-derived growth factor / vascular endothelial growth factor (PDGF/VEGF) family...
    27 KB (3,104 words) - 23:27, 27 March 2024
  • Thumbnail for Tyrosine kinase inhibitor
    example, they have substantially improved outcomes in chronic myelogenous leukemia. They have also been used to treat other diseases, such as idiopathic pulmonary...
    10 KB (1,179 words) - 18:31, 8 August 2024
  • Thumbnail for Insulin-like growth factor
    The insulin-like growth factors (IGFs) are proteins with high sequence similarity to insulin. IGFs are part of a complex system that cells use to communicate...
    14 KB (1,689 words) - 01:31, 19 August 2024
  • Thumbnail for Epidermal growth factor
    Epidermal growth factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor, EGFR. Human EGF is 6-kDa and has...
    17 KB (1,716 words) - 11:48, 25 May 2025
  • Thumbnail for Ciliary neurotrophic factor
    Coupey L, et al. (1996). "Binding interactions of leukemia inhibitory factor and ciliary neurotrophic factor with the different subunits of their high affinity...
    15 KB (1,748 words) - 16:47, 2 October 2024
  • Neurotrophic factor receptors or neurotrophin receptors are a group of growth factor receptors which specifically bind to neurotrophins (neurotrophic factors). Two...
    5 KB (670 words) - 10:25, 10 April 2025
  • Thumbnail for Platelet-derived growth factor receptor
    Platelet-derived growth factor receptors (PDGF-R) are cell surface tyrosine kinase receptors for members of the platelet-derived growth factor (PDGF) family. PDGF...
    13 KB (1,563 words) - 09:00, 13 March 2024
  • Thumbnail for Fibroblast growth factor 21
    Fibroblast growth factor 21 (FGF-21) is a protein that in mammals is encoded by the FGF21 gene. The protein encoded by this gene is a member of the fibroblast...
    24 KB (3,038 words) - 23:40, 29 November 2024
  • Thumbnail for Platelet-derived growth factor
    Platelet-derived growth factor (PDGF) is one among numerous growth factors that regulate cell growth and division. In particular, PDGF plays a significant...
    24 KB (2,882 words) - 15:04, 24 May 2025
  • Thumbnail for Nerve growth factor
    of clinical outcome and prognosis in pediatric core binding factor-acute myeloid leukemia]". Zhonghua Xue Ye Xue Za Zhi = Zhonghua Xueyexue Zazhi (in...
    27 KB (3,118 words) - 21:39, 29 May 2025