Leukemia inhibitory factor, or LIF, is an interleukin 6 class cytokine that affects cell growth by inhibiting differentiation. When LIF levels drop, the...
13 KB (1,583 words) - 04:50, 17 August 2024
Differentiation 118), is a subunit of a receptor for leukemia inhibitory factor. The leukemia inhibitory factor (LIF) is a polyfunctional cytokine that affects...
11 KB (1,325 words) - 16:37, 6 April 2024
unknown. The CNTF family of neurotrophic factors includes ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), interleukin-6 (IL-6), prolactin...
16 KB (1,784 words) - 04:08, 6 January 2024
Implantation (embryology) (section Other factors)
there is no evidence to support their involvement in hatching. Leukemia inhibitory factor (LIF) is a pro-inflammatory cytokine expressed in the endometrium...
51 KB (5,859 words) - 20:34, 3 March 2025
negative regulating factors are known (such as dopamine, leukemia inhibitory factor, some prostaglandins) but few stimulating factor. Its secretion is mediated...
1 KB (181 words) - 14:07, 14 November 2022
motility factor Bone morphogenetic proteins (BMPs) Ciliary neurotrophic factor family Ciliary neurotrophic factor (CNTF) Leukemia inhibitory factor (LIF)...
10 KB (1,131 words) - 18:45, 6 May 2025
growth factors and is frequently added to growth media used for eukaryotic cell culture. A combination of FBS and the cytokine leukemia inhibitory factor was...
7 KB (736 words) - 11:54, 31 July 2024
album A Natural Death "Líf", a song by Hildur Vala Einarsdóttir Leukemia inhibitory factor, a cytokine that affects cell growth and development Laser-induced...
1 KB (189 words) - 19:46, 4 May 2025
group of cytokines. Of these cytokines it most closely resembles leukemia inhibitory factor (LIF) in both structure and function. As yet poorly defined, it...
32 KB (4,317 words) - 12:20, 2 November 2024
Brain-derived neurotrophic factor (BDNF), or abrineurin, is a protein that, in humans, is encoded by the BDNF gene. BDNF is a member of the neurotrophin...
50 KB (5,881 words) - 13:31, 5 May 2025
Colony-stimulating factors (CSFs) are secreted glycoproteins that bind to receptor proteins on the surfaces of committed progenitors in the bone marrow...
3 KB (374 words) - 18:45, 17 July 2023
fibroblast growth factor receptors (FGFR) are, as their name implies, receptors that bind to members of the fibroblast growth factor (FGF) family of proteins...
8 KB (827 words) - 14:53, 16 April 2025
Fibroblast growth factor 2 (FGF-2), also known as basic fibroblast growth factor (bFGF) and FGF-β, is a growth factor and signaling protein encoded by...
22 KB (2,698 words) - 15:56, 25 May 2025
Stem cell factor (also known as SCF, KIT-ligand, KL, or steel factor) is a cytokine that binds to the c-KIT receptor (CD117). SCF can exist both as a transmembrane...
23 KB (2,958 words) - 06:49, 29 April 2025
(BCR-ABL1[T315I]) that is common in chronic myeloid leukemias and adult acute lymphoblastic leukemias which have become resistant to other tyrosine kinase...
16 KB (1,239 words) - 20:04, 29 May 2025
Promyelocytic leukemia protein (PML) (also known as MYL, RNF71, PP8675 or TRIM19) is the protein product of the PML gene. PML protein is a tumor suppressor...
33 KB (4,053 words) - 07:02, 10 July 2024
Insulin-like growth factor 1 (IGF-1), also called somatomedin C, is a hormone similar in molecular structure to insulin which plays an important role in...
34 KB (4,517 words) - 04:19, 9 June 2025
F, et al. (2003). "Vascular endothelial growth factor and its receptors in multiple myeloma". Leukemia. 17 (10): 1961–6. doi:10.1038/sj.leu.2403076. PMID 14513045...
40 KB (4,578 words) - 12:30, 10 September 2024
Hepatocyte growth factor (HGF) or scatter factor (SF) is a paracrine cellular growth, motility and morphogenic factor. It is secreted by mesenchymal cells...
23 KB (2,623 words) - 08:53, 15 March 2025
with gp130, such as cardiotrophin 1 (CT-1), leukemia inhibitory factor (LIF), ciliary neurotrophic factor (CNTF), oncostatin M (OSM), and IL-11. There...
20 KB (2,477 words) - 01:52, 14 June 2025
endothelial growth factor C (VEGF-C) is a protein that is a member of the platelet-derived growth factor / vascular endothelial growth factor (PDGF/VEGF) family...
27 KB (3,104 words) - 23:27, 27 March 2024
example, they have substantially improved outcomes in chronic myelogenous leukemia. They have also been used to treat other diseases, such as idiopathic pulmonary...
10 KB (1,179 words) - 18:31, 8 August 2024
The insulin-like growth factors (IGFs) are proteins with high sequence similarity to insulin. IGFs are part of a complex system that cells use to communicate...
14 KB (1,689 words) - 01:31, 19 August 2024
Epidermal growth factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor, EGFR. Human EGF is 6-kDa and has...
17 KB (1,716 words) - 11:48, 25 May 2025
Coupey L, et al. (1996). "Binding interactions of leukemia inhibitory factor and ciliary neurotrophic factor with the different subunits of their high affinity...
15 KB (1,748 words) - 16:47, 2 October 2024
Neurotrophic factor receptors or neurotrophin receptors are a group of growth factor receptors which specifically bind to neurotrophins (neurotrophic factors). Two...
5 KB (670 words) - 10:25, 10 April 2025
Platelet-derived growth factor receptors (PDGF-R) are cell surface tyrosine kinase receptors for members of the platelet-derived growth factor (PDGF) family. PDGF...
13 KB (1,563 words) - 09:00, 13 March 2024
Fibroblast growth factor 21 (FGF-21) is a protein that in mammals is encoded by the FGF21 gene. The protein encoded by this gene is a member of the fibroblast...
24 KB (3,038 words) - 23:40, 29 November 2024
Platelet-derived growth factor (PDGF) is one among numerous growth factors that regulate cell growth and division. In particular, PDGF plays a significant...
24 KB (2,882 words) - 15:04, 24 May 2025
of clinical outcome and prognosis in pediatric core binding factor-acute myeloid leukemia]". Zhonghua Xue Ye Xue Za Zhi = Zhonghua Xueyexue Zazhi (in...
27 KB (3,118 words) - 21:39, 29 May 2025