• Thumbnail for Linker histone H1 variants
    biology, the linker histone H1 is a protein family forming a critical component of eukaryotic chromatin. H1 histones bind to the linker DNA exiting from...
    15 KB (1,733 words) - 16:01, 30 March 2024
  • Thumbnail for Histone H1
    well studied than the PTMs of other histones. Nucleosome Histone Chromatin Linker histone H1 variants Other histone proteins involved in chromatin: H2A...
    20 KB (2,228 words) - 23:34, 17 July 2025
  • of linker histone (H1) variants, which lack a distinct canonical isoform. The differences between the core canonical histones and their variants can...
    11 KB (1,465 words) - 17:32, 16 July 2025
  • Thumbnail for Histone
    five families of histones, which are designated H1/H5 (linker histones), H2, H3, and H4 (core histones). The nucleosome core is formed of two H2A-H2B dimers...
    91 KB (10,441 words) - 04:20, 28 July 2025
  • Thumbnail for Chromatosome
    nucleosome. Histone H1, and its other variants, are referred to as linker histones. Protruding from the linker histone are linker DNA. Chromatosomes are connected...
    2 KB (223 words) - 19:05, 2 December 2023
  • Thumbnail for Nucleosome
    the DNA entry and exit binding to the linker region of the DNA. Non-condensed nucleosomes without the linker histone resemble "beads on a string of DNA"...
    56 KB (6,672 words) - 18:05, 23 July 2025
  • Thumbnail for Histone H2A
    notable variants include H2A.1, H2A.2, H2A.X, and H2A.Z. H2A variants can be explored using "HistoneDB with Variants" database Changes in variant composition...
    17 KB (2,081 words) - 16:30, 19 July 2025
  • Thumbnail for HIST1H1C
    HIST1H1C (redirect from H1-2)
    is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction...
    6 KB (780 words) - 06:02, 19 July 2025
  • Thumbnail for HIST1H1E
    HIST1H1E (redirect from H1-4)
    is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction...
    8 KB (906 words) - 16:51, 17 July 2025
  • Thumbnail for HIST1H1T
    HIST1H1T (redirect from H1-6)
    is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction...
    4 KB (584 words) - 17:31, 16 July 2025
  • Thumbnail for HIST1H1B
    HIST1H1B (redirect from H1-5)
    is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction...
    9 KB (944 words) - 16:51, 17 July 2025
  • Thumbnail for Solenoid (DNA)
    bent linker DNA which positions sequential nucleosomes adjacent to one another in the helix. The nucleosomes are positioned with the histone H1 proteins...
    17 KB (2,122 words) - 18:25, 17 July 2025
  • Thumbnail for H3F3A
    H3F3A (redirect from Histone H3.3)
    is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction...
    12 KB (1,307 words) - 17:28, 16 July 2025
  • Thumbnail for Histone H2A.Z
    The chromatin fiber is further compacted by the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin...
    9 KB (1,240 words) - 16:52, 17 July 2025
  • Thumbnail for H2AFV
    of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H2A...
    7 KB (638 words) - 05:59, 19 July 2025
  • Thumbnail for Histone H3.1
    the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA...
    7 KB (869 words) - 21:47, 15 July 2025
  • Thumbnail for Histone H2B type 1-C
    is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction...
    5 KB (578 words) - 17:32, 16 July 2025
  • Thumbnail for HIST1H1D
    HIST1H1D (redirect from H1-3)
    wrapped to create repeating units called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and facilitates the compaction...
    5 KB (690 words) - 06:02, 19 July 2025
  • Thumbnail for HIST1H3H
    is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction...
    5 KB (490 words) - 17:32, 16 July 2025
  • interconnected by sections of linker DNA, a far shorter arrangement than pure DNA in solution. In addition to core histones, a linker histone H1 exists that contacts...
    54 KB (6,007 words) - 03:59, 15 July 2025
  • Thumbnail for HIST4H4
    chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin...
    7 KB (946 words) - 06:03, 19 July 2025
  • Thumbnail for Histone octamer
    the histone octamer. Once the wave reaches the end of the histone octamer the excess that was once at the edge is extended into the region of linker DNA...
    19 KB (2,482 words) - 21:47, 15 July 2025
  • pattern of canonical histone loss, particularly in terms of the nucleosome histones H3 and H4 and the linker histone H1. Histone variants with two exons are...
    50 KB (5,523 words) - 18:54, 17 July 2025
  • Thumbnail for HIST1H3B
    the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA...
    9 KB (1,052 words) - 17:32, 16 July 2025
  • Thumbnail for HIST1H2BD
    chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin...
    10 KB (934 words) - 17:32, 16 July 2025
  • Thumbnail for HIST1H4E
    is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction...
    4 KB (461 words) - 06:02, 19 July 2025
  • Thumbnail for HIST1H3G
    is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction...
    5 KB (525 words) - 06:02, 19 July 2025
  • Thumbnail for Valproate
    Valproate (category Histone deacetylase inhibitors)
    affecting GABA levels, blocking voltage-gated sodium channels, inhibiting histone deacetylases, and increasing LEF1. Valproic acid is a branched short-chain...
    83 KB (6,983 words) - 17:38, 18 July 2025
  • Thumbnail for Núria López Bigas
    Biology. Basel Computational Biology Conference Oncogenomics Linker histone H1 variants Fabra, Universitat Pompeu (2016-04-12). "López-Bigas, Nuria"....
    6 KB (612 words) - 18:37, 24 March 2023
  • Thumbnail for HIST1H2BA
    chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin...
    5 KB (712 words) - 17:32, 16 July 2025