• the median lethal dose, LD50 (abbreviation for "lethal dose, 50%"), LC50 (lethal concentration, 50%) or LCt50 is a toxic unit that measures the lethal dose...
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  • sub-populations. The median lethal dose, LD50 (abbreviation for "lethal dose, 50%"), LC50 (lethal concentration, 50%) or LCt50 (lethal concentration and...
    14 KB (1,684 words) - 04:52, 26 June 2024
  • Thumbnail for Median toxic dose
    be approximated to equal doses. Since toxicity need not be lethal, the TD50 is generally lower than the median lethal dose (LD50), and the latter can...
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  • solid with a median lethal dose for acute oral toxicity of not more than 300 mg/kg. Dermal toxicity. A material with a median lethal dose for acute dermal...
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  • frequently determined in animals as lethal dose of a drug for 50% of the population (LD50) divided by the minimum effective dose for 50% of the population (ED50)...
    30 KB (3,753 words) - 04:36, 31 May 2025
  • tolerable dose, MTD, LD0 Minimum lethal concentration, LCmin; Minimum lethal dose, LDmin Median lethal concentration, LC50; Median lethal dose, LD50; Median lethal...
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  • Thumbnail for Ricin
    produced in the seeds of the castor oil plant, Ricinus communis. The median lethal dose (LD50) of ricin for mice is around 22 micrograms per kilogram of body...
    61 KB (6,868 words) - 06:57, 25 May 2025
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    knowledge of this species until its rediscovery in 1972. Based on the median lethal dose value in mice, the venom of the inland taipan is by far the most toxic...
    84 KB (8,307 words) - 23:54, 23 May 2025
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    their venom capabilities or behavioral tendencies. The median lethal dose (LD50) of a venom is the dose required to kill half the members of a tested population...
    145 KB (17,145 words) - 03:42, 31 May 2025
  • effective dose would be substantially less than either the toxic or lethal dose for a drug to be therapeutically relevant. The ED95 is the dose required...
    6 KB (684 words) - 16:56, 21 January 2024
  • dictionary. LD50 is the median lethal dose in toxicology. LD50 may also refer to: L.D. 50 (album), an album by Mudvayne LD 50 Lethal Dose, a 2003 UK film "LD50"...
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    written by Agatha Christie. The probable lethal oral dose in humans is 1.5 to 2 mg/kg. Similarly, the median lethal dose for dogs, cats, and rats ranges from...
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  • Thus the median lethal dose for inhaled A-234 is 0.2 mg (5000 lethal doses in a gram) and is below 0.1 mg for A-230 (10 000 lethal doses in a gram)...
    73 KB (8,110 words) - 06:54, 7 April 2025
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    humans and is considered a teratogen. The median lethal dose of nicotine in humans is unknown. High doses are known to cause nicotine poisoning, organ...
    139 KB (14,454 words) - 21:40, 29 May 2025
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    environment which is linked to respiratory issues and diseases. The LC50 (median lethal dose) for humans has been estimated to be 174 ppm for a 1-hour exposure...
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  • Hormesis – Characteristic of biological processes Median lethal dose – Measurement of lethal dose of substance Therapeutic index – Quantitative measurement...
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  • Effective dose (radiation), a measure of cancer/heritable health risk to the whole body from ionizing radiation Median lethal dose, a measure of the lethal dose...
    2 KB (273 words) - 18:54, 30 September 2024
  • Thumbnail for Potassium cyanide
    hypoxia/cerebral hypoxia. The expected LD100 dose (human) for potassium cyanide is 200–300 mg while the median lethal dose LD50 is estimated at 140 mg. Due to...
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  • consume the substance. Certain safety factor Lowest published lethal dose (LDLo) Median lethal dose (LD50) "CDC - Abbreviations for IDLH Documentation - NIOSH...
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  • Thumbnail for Abrin
    of the rosary pea (or jequirity pea), Abrus precatorius. It has a median lethal dose of 0.7 micrograms per kilogram of body mass when given to mice intravenously...
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  • Thumbnail for Tetrahydrocannabinol
    pain that may persist for months to years after discontinuation. The median lethal dose of THC in humans is not fully known as there is conflicting evidence...
    62 KB (5,597 words) - 22:21, 29 May 2025
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    Sprague-Dawley rats (lab rats) were used as test subjects. The oral median lethal dose in male lab rats was determined to be 23.58 mL/kg body weight (BW)...
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    agent, paraformaldehyde is a potential carcinogen. Its acute oral median lethal dose in rats is 592 mg/kg. 1,3,5-Trioxane (metaformaldehyde), the cyclic...
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    treatment with precipitated chalk (i.e., calcium carbonate). The LD50 (median lethal dose) for pure oxalic acid in rats is about 375 mg/kg body weight, or about...
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  • absolutely absent in the doses below the threshold dose. The median lethal dose (LD50) of a substance is defined as the dose that leads to death in 50%...
    23 KB (2,910 words) - 07:39, 28 May 2025
  • Thumbnail for Adipic acid
    carboxylic acids, is a mild skin irritant. It is mildly toxic, with a median lethal dose of 3600 mg/kg for oral ingestion by rats. The production of adipic...
    14 KB (1,281 words) - 03:13, 20 May 2025
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    particulate emitting radionuclides may be fatal. For example, the median lethal dose (LD-50) for ingested polonium-210 is 240 μCi; about 53.5 nanograms...
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  • heterotrimer is about 46,000 Dalton; comprising 1:1:1 α, β and γ monomers. Median lethal dose (LD50) for mice is around 1–2 μg/kg (subcutaneous injection). Taipoxin...
    17 KB (2,007 words) - 23:12, 20 September 2024
  • Thumbnail for ADME
    (ADME-Tox or ADMET). Parameters used to characterize toxicity include the median lethal dose (LD50) and therapeutic index. Computational chemists try to predict...
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  • a median lethal dose of 5 Sv). People in well-built shelters would be safe due to radiation shielding. After one half-life of 5.27 years, the dose rate...
    26 KB (3,203 words) - 07:34, 27 May 2025