The norepinephrine transporter (NET), also known as noradrenaline transporter (NAT), is a protein that in humans is encoded by the solute carrier family...
33 KB (3,478 words) - 15:43, 11 January 2025
competitively and/or noncompetitively inhibiting the norepinephrine transporter (NET) and dopamine transporter (DAT). NDRIs are used clinically in the treatment...
5 KB (463 words) - 05:51, 28 January 2025
neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline) by blocking the action of the norepinephrine transporter (NET). This in turn...
7 KB (678 words) - 15:01, 12 December 2024
depression and attention deficit hyperactivity disorder (ADHD). The norepinephrine transporter (NET) serves as the fundamental mechanism for the inactivation...
34 KB (3,807 words) - 20:19, 12 January 2025
three major classes are serotonin transporters (SERTs), dopamine transporters (DATs), and norepinephrine transporters (NETs) and are responsible for the...
21 KB (2,342 words) - 15:34, 14 September 2024
cortex, where evidence points to a possibly larger role of the norepinephrine transporter. DAT is implicated in a number of dopamine-related disorders,...
84 KB (9,201 words) - 10:39, 12 December 2024
inhibitors (SSRIs) and norepinephrine reuptake inhibitors (NRIs), which act upon single neurotransmitters. The human serotonin transporter (SERT) and noradrenaline...
84 KB (8,211 words) - 06:58, 1 May 2025
Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and...
60 KB (6,685 words) - 14:27, 11 April 2025
simultaneous inhibition of the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT), respectively, increasing their...
138 KB (16,223 words) - 07:48, 6 May 2025
significant association. Attempts to find a correlation between norepinephrine transporter polymorphisms and depression have yielded negative results. One...
128 KB (15,013 words) - 05:13, 28 April 2025
Dopamine reuptake inhibitor (redirect from Dopamine transporter "inverse agonist")
very selective for the dopamine transporter, with little to no effect on the norepinephrine and serotonin transporters 4-Hydroxy-1-methyl-4-(4-methylphenyl)-3-piperidyl...
19 KB (1,930 words) - 01:50, 6 March 2025
epinephrine and norepinephrine; subtypes include α1, α2, β1, β2, and β3 receptors Adrenergic transporter (norepinephrine transporter), a protein transporting...
3 KB (286 words) - 18:10, 25 July 2024
proteins for monoamines (i.e., the dopamine transporter, norepinephrine transporter, and serotonin transporter) in monoamine neurons. Other VMAT2 inhibitors...
29 KB (3,347 words) - 04:21, 10 March 2025
(MATs), which include the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT). This in turn results in an increase...
20 KB (1,388 words) - 21:36, 30 January 2025
Ampreloxetine (category Norepinephrine reuptake inhibitors)
(NOH). It shows high affinity for both the norepinephrine transporter (NET) and the serotonin transporter (SERT), with 4-fold selectivity for the NET...
5 KB (335 words) - 13:52, 4 December 2024
A norepinephrine releasing agent (NRA), also known as an adrenergic releasing agent, is a catecholaminergic type of drug that induces the release of norepinephrine...
18 KB (1,747 words) - 15:13, 13 February 2025
Membrane transport protein (redirect from Membrane transporter)
transporters (EAATs) EAAT1 EAAT2 EAAT3 EAAT4 EAAT5 Glucose transporter Monoamine transporters, including: Dopamine transporter (DAT) Norepinephrine transporter...
26 KB (2,656 words) - 14:08, 8 March 2025
autonomic cardiac neuropathy, although reduced expression of the norepinephrine transporter may also result in impaired MIBG reuptake and has been implicated...
99 KB (9,914 words) - 05:14, 22 April 2025
Monoamine transporters, including: Dopamine transporter (DAT) Norepinephrine transporter (NET) Serotonin transporter (SERT) Vesicular monoamine transporter 1...
9 KB (988 words) - 00:34, 19 August 2023
methylphenidate lose their ability to elevate brain dopamine but not norepinephrine in dopamine transporter (DAT) knockout mice and have been found to decrease locomotor...
114 KB (12,379 words) - 00:02, 10 May 2025
exceptionally difficult to tease apart affinity for the DAT from the norepinephrine transporter (NET) and inhibit the reuptake of dopamine alone. As a result...
16 KB (1,782 words) - 09:16, 31 October 2024
and pinoxepin. Further work on these compounds led to tametraline, a norepinephrine and weaker dopamine reuptake inhibitor. Development of tametraline was...
104 KB (10,669 words) - 04:25, 12 May 2025
Atomoxetine (category Serotonin–norepinephrine reuptake inhibitors)
Atomoxetine, formerly sold under the brand name Strattera, is a selective norepinephrine reuptake inhibitor (sNRI) medication used to treat attention deficit...
72 KB (6,251 words) - 04:39, 12 May 2025
inhibit serotonin transporter (SERT) in the brain and have negligible effects on dopamine transporter (DAT) and norepinephrine transporter (NET). Inhibiting...
51 KB (5,336 words) - 14:09, 1 April 2025
the monoamine transporters (MATs), including the serotonin transporter (SERT), norepinephrine transporter (NET), and/or dopamine transporter (DAT), causing...
263 KB (22,099 words) - 23:59, 9 May 2025
transports monoamine neurotransmitters – such as dopamine, serotonin, norepinephrine, epinephrine, and histamine – into the vesicles, which release the neurotransmitters...
43 KB (4,993 words) - 04:26, 10 March 2025
Reboxetine (category Norepinephrine reuptake inhibitors)
fairly selective norepinephrine reuptake inhibitor (NRI), with approximately 20-fold selectivity for the norepinephrine transporter (NET) over the serotonin...
29 KB (2,701 words) - 14:51, 18 April 2025
Methylphenidate (category Norepinephrine–dopamine reuptake inhibitors)
monoamine transporters when they are co-administered.[better source needed] Methylphenidate has both dopamine transporter and norepinephrine transporter binding...
155 KB (14,197 words) - 18:35, 10 May 2025
monoamine transporters, with pure SSRIs having strong affinity for the serotonin transporter and only weak affinity for the norepinephrine and dopamine...
154 KB (16,391 words) - 16:27, 18 May 2025
pharmacological profile, distinct from cocaine, at dopamine, serotonin, and norepinephrine transporter sites. The study highlighted that "hydrophobicity and conformational...
3 KB (260 words) - 23:18, 31 January 2025