• A nuclear export signal (NES) is a short target peptide containing 4 hydrophobic residues in a protein that targets it for export from the cell nucleus...
    10 KB (1,282 words) - 04:58, 26 May 2025
  • proteins may share the same NLS. An NLS has the opposite function of a nuclear export signal (NES), which targets proteins out of the nucleus. These types of...
    15 KB (2,036 words) - 22:39, 23 May 2025
  • Thumbnail for TAR DNA-binding protein 43
    The protein sequence also has a nuclear localization signal (NLS, residues 82–98), a former nuclear export signal (NES residues 239–250) and 3 putative...
    40 KB (4,560 words) - 00:13, 27 May 2025
  • Thumbnail for XPO1
    structure. It was later shown to be the nuclear transport receptor for cargos with leucine-rich nuclear export signals (NES). The structural details of the...
    18 KB (2,034 words) - 22:35, 29 May 2025
  • Thumbnail for Rev (HIV)
    ribonucleoprotein complex. The domain also contains a nuclear localization signal. Rev's nuclear export signal is located in residues 71–82 of the C-terminal...
    25 KB (3,100 words) - 18:36, 24 May 2025
  • Isoform-selective protein kinase C agonist Interaction between two proteins Nuclear export signal in a protein HEK 293 cells were adapted to grow in suspension culture...
    25 KB (3,064 words) - 15:43, 11 July 2025
  • Thumbnail for Nuclear pore complex
    pathways through the NPC for various RNA classes. RNA export is signal-mediated, with nuclear export signals (NES) present in RNA-binding proteins, except for...
    29 KB (3,337 words) - 04:11, 4 July 2025
  • subunits are exported from the nucleus due to association with exportins, which bind signaling sequences called nuclear export signals (NES). The ability...
    8 KB (976 words) - 22:34, 1 July 2024
  • (protein), a human gene and protein Nuclear export signal, an amino acid sequence causing a protein to be exported from the nucleus to the cytoplasm Night...
    4 KB (531 words) - 06:36, 3 March 2025
  • Thumbnail for Cell nucleus
    as nuclear localization signals, which are bound by importins, while those transported from the nucleus to the cytoplasm carry nuclear export signals bound...
    88 KB (10,011 words) - 23:05, 23 June 2025
  • CS, Dias AP, Rapoport TA (December 2007). "The signal sequence coding region promotes nuclear export of mRNA". PLOS Biology. 5 (12): e322. doi:10.1371/journal...
    15 KB (1,777 words) - 07:49, 20 May 2025
  • Thumbnail for HNRNPA1
    region downstream from the RGG box, acts as both a nuclear localization and nuclear export signal. The encoded protein is involved in the packaging of...
    15 KB (1,945 words) - 23:45, 19 April 2025
  • 1999). "Nuclear import of hepatic glucokinase depends upon glucokinase regulatory protein, whereas export is due to a nuclear export signal sequence...
    16 KB (1,893 words) - 12:12, 30 June 2025
  • Thumbnail for G2 phase
    mechanism is highly conserved. Nuclear export is also inactivated by phosphorylation of cyclin B1's nuclear export signal (NES). The regulators of these...
    22 KB (2,818 words) - 07:39, 3 June 2024
  • Thumbnail for Ribosome biogenesis
    dependent fashion. It recognizes molecules that have leucine-rich nuclear export signals. The Crm1 is pulled to the large 60S subunit by the help of an adapter...
    17 KB (2,273 words) - 07:08, 20 May 2025
  • Thumbnail for Dentatorubral–pallidoluysian atrophy
    residues. It contains a putative nuclear localization signal in the N-terminus of the protein and a putative nuclear export signal in the C-terminus. ATN1 is...
    28 KB (2,928 words) - 22:52, 8 July 2025
  • Thumbnail for Ran (protein)
    Ran (protein) (category Cell signaling)
    Ohno M, Yoshida M, Mattaj IW (1997). "CRM1 is an export receptor for leucine-rich nuclear export signals". Cell. 90 (6): 1051–60. doi:10.1016/S0092-8674(00)80371-2...
    17 KB (1,948 words) - 02:22, 27 May 2025
  • Thumbnail for Alpha-1-B glycoprotein
    NetNES 1.1 program predicted the leucine at residue 47 to be a nuclear export signal. The NetNGlyc 1.0 program predicted four N-glycosylation sites -...
    15 KB (1,379 words) - 02:50, 29 November 2023
  • nuclear deal. In the days before the attack, Iran increased its oil exports, fearing a U.S. attack on its oil facilities. Iran claimed that nuclear material...
    164 KB (14,152 words) - 10:08, 12 July 2025
  • Thumbnail for LPP (gene)
    "LPP, an Actin Cytoskeleton Protein Related to Zyxin, Harbors a Nuclear Export Signal and Transcriptional Activation Capacity". Mol. Biol. Cell. 11 (1):...
    10 KB (1,013 words) - 04:10, 28 June 2025
  • Thumbnail for CTNNBL1
    contains an acidic domain, a putative bipartite nuclear localization signal, a nuclear export signal, a leucine-isoleucine zipper, and phosphorylation...
    5 KB (595 words) - 01:55, 5 October 2022
  • Thumbnail for EIF4ENIF1
    mediate nuclear import of eIF4E. It is predominantly cytoplasmic;its own nuclear import is regulated by a nuclear localization signal and nuclear export signals...
    5 KB (637 words) - 23:12, 2 December 2023
  • Thumbnail for TFEB
    R, Borden KLB, Filippakopoulos P, Goding CR (Jul 2018). "A TFEB nuclear export signal integrates amino acid supply and glucose availability". Nature Communications...
    18 KB (2,230 words) - 00:15, 19 January 2025
  • require nuclear localization signals identifiable by molecular chaperones in order to cross the nuclear envelope. Contrast nuclear export signal. nuclear membrane...
    301 KB (26,725 words) - 15:05, 3 July 2025
  • Thumbnail for List of states with nuclear weapons
    waiver of export restrictions for India, approval by the US Congress and culminating in the signature of US–India agreement for civil nuclear cooperation...
    100 KB (8,891 words) - 09:13, 3 July 2025
  • Thumbnail for Niche (protein structural motif)
    the nuclear export receptor CRM1 is recognised specifically by a niche conformation that has to be adopted as a key part of the nuclear export signal of...
    7 KB (859 words) - 04:03, 29 April 2024
  • Thumbnail for C1orf122
    since it is predicted to have a nuclear export signal, it is kept in the cytoplasm even in telophase when the nuclear envelope disassembles. Human C1orf122...
    8 KB (912 words) - 01:46, 4 November 2023
  • Thumbnail for USP4
    bears a functional nuclear localization signal (NLS) 766QPQKKKK772 and a nuclear export signal (NES) 133VEVYLLELKL142. Those signals initiate the translocation...
    9 KB (979 words) - 06:17, 15 April 2024
  • Thumbnail for Histone acetylation and deacetylation
    regions, one called a Nuclear Localization Signal (NLS) as well as a Nuclear Export Signal (NES). The NLS functions as a signal for nuclear action while an...
    58 KB (7,027 words) - 19:10, 31 May 2025
  • Thumbnail for NUPL2
    "A new nucleoporin-like protein interacts with both HIV-1 Rev nuclear export signal and CRM-1". J Biol Chem. 274 (24): 17309–17317. doi:10.1074/jbc...
    7 KB (643 words) - 23:55, 3 March 2023