• Thumbnail for Pituitary-specific positive transcription factor 1
    POU class 1 homeobox 1, also known as pituitary-specific positive transcription factor 1 (PIT1), POU domain, class 1, transcription factor 1 (POU1F1) and...
    11 KB (1,372 words) - 18:38, 30 January 2024
  • Bolshoy Pit, a tributary of the Yenisei, Russia Pituitary-specific positive transcription factor 1 (PIT-1), a gene The Pit (disambiguation) Pitt (disambiguation)...
    4 KB (618 words) - 23:26, 8 April 2025
  • "Human growth hormone-releasing factor (hGRF)1-29-albumin bioconjugates activate the GRF receptor on the anterior pituitary in rats: identification of CJC-1295...
    12 KB (1,289 words) - 21:00, 29 May 2025
  • Thumbnail for Steroidogenic factor 1
    The steroidogenic factor 1 (SF-1) protein is a transcription factor involved in sex determination by controlling the activity of genes related to the...
    29 KB (3,478 words) - 16:38, 23 May 2025
  • Thumbnail for POU4F1
    POU transcription factors Pit1 (Pituitary-specific positive transcription factor 1, Pou1f1), Oct1 (Pou2f1), and the Caenorhabditis elegans factor Unc86...
    17 KB (2,159 words) - 03:13, 3 December 2023
  • Thumbnail for Paracrine signaling
    nucleus, where they act as transcription factors and either up-regulate or down-regulate in the expression of a target gene. Specific TGF-β ligands will result...
    45 KB (4,879 words) - 07:05, 7 April 2025
  • Thumbnail for NK2 homeobox 1
    the NKX2-1 gene. Thyroid transcription factor-1 (TTF-1) is a protein that regulates transcription of genes specific for the thyroid, lung, and diencephalon...
    20 KB (2,210 words) - 23:55, 15 June 2025
  • Thumbnail for PITX1
    PITX1 (category Transcription factors)
    dominant clubfoot. PITX1 has been shown to interact with pituitary-specific positive transcription factor 1. GRCh38: Ensembl release 89: ENSG00000069011 – Ensembl...
    11 KB (1,277 words) - 14:31, 30 May 2025
  • Thumbnail for Fibroblast growth factor 2
    NANOG and GATA4 (transcription factors essential for proper cell differentiation and embryonic development), indicating a specific role of FGF2 in PE...
    22 KB (2,698 words) - 15:56, 25 May 2025
  • cell-to-cell interactions, signaling pathways, and numerous transcription factors. Of the pituitary endocrine cells, the gonadotropic cells are the last to...
    15 KB (1,681 words) - 20:16, 4 June 2025
  • Thumbnail for Growth hormone 1
    Growth hormone 1, also known as pituitary growth hormone or simply as growth hormone (GH) somatotropin, is a protein that in humans is encoded by the GH1...
    3 KB (404 words) - 17:33, 11 November 2023
  • Thumbnail for Luteinizing hormone
    Luteinizing hormone (category Hormones of the hypothalamus-pituitary-gonad axis)
    stimulating the release of LH from the anterior pituitary. Some studies, however, attribute the LH surge to positive feedback from estradiol after production...
    36 KB (3,608 words) - 15:42, 17 February 2025
  • Thumbnail for IRF3
    regulatory factor 3, also known as IRF3, is an interferon regulatory factor. IRF3 is a member of the interferon regulatory transcription factor (IRF) family...
    12 KB (1,493 words) - 01:36, 11 December 2023
  • from the names of three transcription factors: the Pituitary-specific Pit-1 the Octamer transcription factor proteins Oct-1 and Oct-2 (octamer sequence...
    9 KB (999 words) - 14:46, 22 March 2023
  • Thumbnail for Growth hormone
    insulin-like growth factor 1 (IGF-1) and increases the concentration of glucose and free fatty acids. It is a type of mitogen which is specific only to the receptors...
    58 KB (6,716 words) - 15:42, 13 June 2025
  • Thumbnail for Prolactin
    Prolactin (category Anterior pituitary hormones)
    anterior pituitary, decidua, myometrium, breast, lymphocytes, leukocytes and prostate. Pituitary prolactin is controlled by the Pit-1 transcription factor, which...
    58 KB (6,049 words) - 23:34, 22 May 2025
  • Thumbnail for Insulin-like growth factor 1
    Insulin-like growth factor 1 (IGF-1), also called somatomedin C, is a hormone similar in molecular structure to insulin which plays an important role...
    34 KB (4,517 words) - 04:19, 9 June 2025
  • Growth hormone (GH), which is secreted from the pituitary gland, and insulin-like growth factor 1 (IGF-1), which is produced in the body in response to...
    59 KB (6,495 words) - 19:13, 23 May 2025
  • Thumbnail for Nerve growth factor
    c-Jun. The activated transcription factor c-Jun regulates nuclear transcription via AP-1 to increase pro-apoptotic gene transcription. There is evidence...
    27 KB (3,118 words) - 21:39, 29 May 2025
  • Thumbnail for Host cell factor C1
    proteins interacting with transcription factor Sp1 identified in a two-hybrid screening". Molecular and Cellular Biochemistry. 210 (1–2): 131–42. doi:10.1023/A:1007177623283...
    15 KB (1,794 words) - 02:09, 3 December 2023
  • Thumbnail for Epidermal growth factor receptor
    positive and negative domains within the epidermal growth factor receptor COOH-terminal region for signal transducer and activator of transcription (STAT)...
    60 KB (6,879 words) - 01:06, 1 March 2025
  • Thumbnail for Platelet-derived growth factor receptor
    phosphorylates a variety of cytoplasmic substrates, as well as transcription factors, when translocated into the nucleus. MAPK family members have been...
    13 KB (1,563 words) - 09:00, 13 March 2024
  • Thumbnail for Proopiomelanocortin
    amino acid residues. POMC is synthesized in corticotrophs of the anterior pituitary from the 267-amino-acid-long polypeptide precursor pre-pro-opiomelanocortin...
    20 KB (2,226 words) - 20:43, 22 March 2025
  • Thumbnail for Hepatocyte growth factor receptor
    growth genes. ETS1 activates MET transcription in vitro. MET transcription is activated by hypoxia-inducible factor 1 (HIF1), which is activated by low...
    59 KB (6,731 words) - 05:32, 23 May 2025
  • Thumbnail for Brain-derived neurotrophic factor
    of a Cre regulatory component, suggesting a putative role for the transcription factor CREB and the source of BDNF's activity-dependent effects . There...
    50 KB (5,881 words) - 13:31, 5 May 2025
  • Thumbnail for Ghrelin
    the secretion of gastric acid. Ghrelin activates cells in the anterior pituitary gland and hypothalamic arcuate nucleus, including neuropeptide Y neurons...
    44 KB (4,802 words) - 17:42, 20 March 2025
  • Thumbnail for LHX3
    LHX3 (category Transcription factors)
    cysteine-rich zinc-binding domain. The encoded protein is a transcription factor that is required for pituitary development and motor neuron specification. Two transcript...
    10 KB (1,092 words) - 07:32, 5 February 2025
  • been found to inhibit BDNF transcription. In the hypothalamic-pituitary-adrenal axis (HPA axis), corticotropin-releasing factor (CRF) is secreted by the...
    35 KB (4,421 words) - 01:52, 22 November 2024
  • Thumbnail for POU3F2
    mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1; MIM 164175) and Oct2 (POU2F2; MIM 164176), and the pituitary protein...
    10 KB (1,170 words) - 06:11, 13 May 2024
  • Thumbnail for Activin and inhibin
    SMAD4 through multimerization, resulting in their modulation as transcription factor complexes responsible for the expression of a large variety of genes...
    26 KB (2,560 words) - 03:10, 2 June 2025