• Thumbnail for Protein–protein interaction
    Proteinprotein interactions (PPIs) are physical contacts of high specificity established between two or more protein molecules as a result of biochemical...
    74 KB (8,383 words) - 01:02, 20 June 2025
  • Proteinprotein interaction screening refers to the identification of Proteinprotein interaction with high-throughput screening methods such as computer-...
    6 KB (726 words) - 13:48, 18 November 2021
  • Thumbnail for Two-hybrid screening
    Two-hybrid screening (originally known as yeast two-hybrid system or Y2H) is a molecular biology technique used to discover proteinprotein interactions (PPIs)...
    47 KB (6,112 words) - 20:23, 24 May 2025
  • Proteinprotein interaction prediction is a field combining bioinformatics and structural biology in an attempt to identify and catalog physical interactions...
    25 KB (2,915 words) - 05:18, 2 June 2025
  • Thumbnail for DNA-binding protein
    Zell A, Harter K, Wanke D (2013). "Screening for protein-DNA interactions by automatable DNA-protein interaction ELISA". PLOS ONE. 8 (10): e75177. Bibcode:2013PLoSO...
    22 KB (2,637 words) - 06:01, 3 April 2025
  • to investigate proteinprotein interactions which are the physical contacts of high specificity established between two or more protein molecules involving...
    36 KB (4,515 words) - 02:27, 3 December 2024
  • Thumbnail for Protein
    contributed an understanding of protein folding and structure mediated by hydrophobic interactions. The first protein to have its amino acid chain sequenced...
    105 KB (10,969 words) - 16:27, 26 June 2025
  • Thumbnail for P53
    P53 (redirect from Protein P53)
    p73alpha by SUMO-1. Two-hybrid screening with p73 identifies novel SUMO-1-interacting proteins and a SUMO-1 interaction motif". The Journal of Biological...
    131 KB (14,423 words) - 10:16, 24 June 2025
  • Thumbnail for Protein dimer
    receptors modeling, activation, interactions and virtual screening (1st ed.). Academic Press. Matthews, Jacqueline M. Protein Dimerization and Oligomerization...
    7 KB (697 words) - 00:43, 24 June 2025
  • biology, a protein-fragment complementation assay, or PCA, is a method for the identification and quantification of proteinprotein interactions. In the...
    12 KB (1,319 words) - 02:51, 17 March 2025
  • Thumbnail for Green fluorescent protein
    The green fluorescent protein (GFP) is a protein that exhibits green fluorescence when exposed to light in the blue to ultraviolet range. The label GFP...
    66 KB (7,627 words) - 08:51, 21 June 2025
  • detailed knowledge of protein structure and function, and advances in high-throughput screening, may greatly expand the abilities of protein engineering. Eventually...
    58 KB (7,430 words) - 23:57, 9 June 2025
  • Protein–protein interactions can be designed using protein design algorithms because the principles that rule protein stability also rule proteinprotein binding...
    64 KB (7,746 words) - 19:32, 18 June 2025
  • Thumbnail for Virtual screening
    are most likely to bind to a drug target, typically a protein receptor or enzyme. Virtual screening has been defined as "automatically evaluating very large...
    34 KB (4,019 words) - 11:59, 23 June 2025
  • Thumbnail for Protein arginine methyltransferase 5
    lead to development of protein-protein interaction (PPI) inhibitors, modulating binding between PRMT5 and the adaptor proteins. Furthermore, Asberry and...
    13 KB (1,410 words) - 04:58, 17 June 2024
  • antibody, enzyme and substrate, receptor and ligand, or protein and nucleic acid binding interactions are frequently exploited for isolation of various biomolecules...
    29 KB (3,433 words) - 02:47, 31 May 2025
  • Thumbnail for Coronavirus spike protein
    of the protein furthest from the viral surface while the S2 regions form a flexible "stalk" containing most of the protein-protein interactions that hold...
    75 KB (7,317 words) - 09:24, 25 June 2025
  • a protein receptor or enzyme. Pharmaceutical research employs docking techniques for a variety of purposes, most notably in the virtual screening of...
    11 KB (1,453 words) - 07:19, 26 October 2023
  • Thumbnail for Purinosome
    form mesoscale punctuations in cells. In E. coli, binary protein-protein interaction screening have shown the potential existence of a bacterial purinosome...
    16 KB (1,672 words) - 15:30, 26 November 2024
  • Thumbnail for Docking (molecular)
    Docking (molecular) (category Protein structure)
    out whether they can bind at the protein's active site, and are usually scalable to even protein-protein interactions. They are also much more amenable...
    34 KB (4,015 words) - 21:27, 6 June 2025
  • Thumbnail for Bimolecular fluorescence complementation
    Bimolecular fluorescence complementation (category Proteinprotein interaction assays)
    technology typically used to validate protein interactions. It is based on the association of fluorescent protein fragments that are attached to components...
    46 KB (5,192 words) - 21:42, 24 June 2025
  • Thumbnail for Phage display
    Phage display (category Proteinprotein interaction assays)
    study of proteinprotein, protein–peptide, and protein–DNA interactions that uses bacteriophages (viruses that infect bacteria) to connect proteins with the...
    38 KB (4,630 words) - 03:13, 22 June 2024
  • Thumbnail for Huntingtin
    epithelial polarity through its interaction with RAB11A. Huntingtin has been found to interact directly with at least 19 other proteins, of which six are used...
    33 KB (3,723 words) - 16:43, 23 June 2025
  • main substrate is insulin-like growth factor binding proteins. Pappalysin-1 is also used in screening tests for Down syndrome. PAPPA encodes a secreted metalloproteinase...
    5 KB (562 words) - 10:00, 27 March 2024
  • Thumbnail for Oxysterol-binding protein
    part in protein-protein interactions, but it is not known for certain. In some proteins, it also contributes to the localization of each protein to a membrane...
    21 KB (2,071 words) - 13:45, 14 June 2025
  • Thumbnail for CREB-binding protein
    interact with promoter elements; it is brought to the site via protein-protein interactions that are the result of its different structural domains complexing...
    52 KB (5,272 words) - 02:33, 25 May 2025
  • Thumbnail for Protein crystallization
    Protein crystallization is the process of formation of a regular array of individual protein molecules stabilized by crystal contacts. If the crystal is...
    23 KB (2,718 words) - 11:11, 25 May 2025
  • Thumbnail for Protein FAM46B
    gene. FAM46B contains one protein domain of unknown function, DUF1693. Yeast two-hybrid screening has identified three proteins that physically interact...
    16 KB (1,637 words) - 03:03, 10 March 2024
  • 2020-02-12. "About | rDock". Retrieved 2020-02-12. "Protein-ligand docking bioinformatics tools | Interaction analysis". omicX. Retrieved 2019-05-23....
    4 KB (109 words) - 12:40, 21 February 2024
  • Thumbnail for Myelin protein zero
    myelin sheath by participating in homotypic interactions with other myelin protein zero proteins. Myelin protein zero's extracellular domain binds to the...
    19 KB (2,239 words) - 04:21, 16 May 2025