• Thumbnail for Pyruvate dehydrogenase
    Pyruvate dehydrogenase is an enzyme that catalyzes the reaction of pyruvate and a lipoamide to give the acetylated dihydrolipoamide and carbon dioxide...
    13 KB (1,283 words) - 23:40, 16 April 2025
  • Thumbnail for Pyruvate dehydrogenase complex
    Pyruvate dehydrogenase complex (PDC) is a complex of three enzymes that converts pyruvate into acetyl-CoA by a process called pyruvate decarboxylation...
    31 KB (3,654 words) - 12:18, 23 May 2025
  • Thumbnail for Pyruvate decarboxylation
    conversion of pyruvate into acetyl-CoA by the enzyme complex pyruvate dehydrogenase complex. The reaction may be simplified as: Pyruvate + NAD+ + CoA →...
    4 KB (338 words) - 21:27, 23 May 2025
  • Pyruvate dehydrogenase deficiency (also known as pyruvate dehydrogenase complex deficiency or PDCD or PDH deficiency) is a rare neurodegenerative disorder...
    20 KB (2,225 words) - 19:35, 15 May 2025
  • Thumbnail for Lactate dehydrogenase
    Lactate dehydrogenase (LDH or LD) is an enzyme found in nearly all living cells. LDH catalyzes the conversion of pyruvate to lactate and back, as it converts...
    42 KB (4,795 words) - 15:37, 5 February 2025
  • Thumbnail for Pyruvate dehydrogenase lipoamide kinase isozyme 1
    Pyruvate dehydrogenase lipoamide kinase isozyme 1, mitochondrial is an enzyme that in humans is encoded by the PDK1 gene. It codes for an isozyme of pyruvate...
    12 KB (1,616 words) - 09:57, 3 June 2024
  • Thumbnail for Pyruvate dehydrogenase kinase
    Pyruvate dehydrogenase kinase (also pyruvate dehydrogenase complex kinase, PDC kinase, or PDK; EC 2.7.11.2) is a kinase enzyme which acts to inactivate...
    14 KB (1,711 words) - 16:27, 25 October 2023
  • Pyruvic acid (redirect from Pyruvate)
    "GlycolysisGluconeogenesis_WP534". Pyruvate decarboxylation by the pyruvate dehydrogenase complex produces acetyl-CoA. Carboxylation by pyruvate carboxylase produces...
    16 KB (1,231 words) - 11:51, 2 July 2025
  • Thumbnail for Pyruvate dehydrogenase (lipoamide) alpha 1
    Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial is an enzyme that in humans is encoded by the PDHA1 gene.The pyruvate dehydrogenase...
    22 KB (2,885 words) - 20:23, 2 January 2024
  • Thumbnail for Pyruvate dehydrogenase (lipoamide) beta
    Pyruvate dehydrogenase (lipoamide) beta, also known as pyruvate dehydrogenase E1 component subunit beta, mitochondrial or PDHE1-B is an enzyme that in...
    20 KB (2,645 words) - 23:33, 24 May 2025
  • Pyruvate dehydrogenase is a type of enzyme. Pyruvate dehydrogenase may specifically refer to: Pyruvate dehydrogenase (cytochrome) Pyruvate dehydrogenase...
    386 bytes (68 words) - 14:34, 20 October 2023
  • commonly known for its role in the citric acid cycle. Much like pyruvate dehydrogenase complex (PDC), this enzyme forms a complex composed of three components:...
    17 KB (1,893 words) - 21:13, 17 June 2025
  • Thumbnail for Lipoic acid
    of enzymes: pyruvate dehydrogenase, α-ketoglutarate dehydrogenase, the glycine cleavage system, branched-chain alpha-keto acid dehydrogenase, and the α-oxo(keto)adipate...
    49 KB (4,977 words) - 09:25, 15 June 2025
  • Thumbnail for Dihydrolipoyl transacetylase
    component of the multienzyme pyruvate dehydrogenase complex. The pyruvate dehydrogenase complex is responsible for the pyruvate decarboxylation step that...
    21 KB (2,487 words) - 13:36, 24 May 2025
  • Thumbnail for Pyruvate dehydrogenase phosphatase
    reverse the effects of pyruvate dehydrogenase kinase upon pyruvate dehydrogenase, activating pyruvate dehydrogenase. Pyruvate dehydrogenase (E1) is one of the...
    10 KB (1,182 words) - 20:23, 10 November 2022
  • mitochondrial α-ketoacid dehydrogenase complex family, which also includes pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase, key enzymes that function...
    16 KB (1,781 words) - 18:08, 24 April 2024
  • Thumbnail for PDK4
    Pyruvate dehydrogenase lipoamide kinase isozyme 4, mitochondrial (PDK4) is an enzyme that in humans is encoded by the PDK4 gene. It codes for an isozyme...
    20 KB (2,534 words) - 23:35, 3 April 2025
  • Thumbnail for Tumor hypoxia
    dehydrogenase (GAPDH), phosphoglycerate kinase (PGK), phosphoglycerate mutase (PGM), enolase 1 (ENOA), pyruvate kinase (PK), pyruvate dehydrogenase kinase...
    53 KB (5,638 words) - 06:06, 23 May 2025
  • Thumbnail for Dihydrolipoamide dehydrogenase
    "How dihydrolipoamide dehydrogenase-binding protein binds dihydrolipoamide dehydrogenase in the human pyruvate dehydrogenase complex". The Journal of...
    21 KB (2,346 words) - 00:15, 8 June 2024
  • carboxylic malic acid, isocitric acid, etc. Pyruvate catalytic reaction catalyzed by pyruvate dehydrogenase system is a special decarboxylation method...
    12 KB (1,572 words) - 10:59, 26 June 2025
  • Thumbnail for Citric acid cycle
    breakdown of sugars by glycolysis which yield pyruvate that in turn is decarboxylated by the pyruvate dehydrogenase complex generating acetyl-CoA according...
    55 KB (6,095 words) - 01:17, 25 May 2025
  • Thumbnail for Acetyl-CoA
    conversion of pyruvate into acetyl-CoA is referred to as the pyruvate dehydrogenase reaction. It is catalyzed by the pyruvate dehydrogenase complex. Other...
    27 KB (2,577 words) - 06:37, 24 June 2025
  • Thumbnail for PDK2
    Pyruvate dehydrogenase kinase isoform 2 (PDK2) also known as pyruvate dehydrogenase lipoamide kinase isozyme 2, mitochondrial is an enzyme that in humans...
    15 KB (1,908 words) - 17:28, 11 June 2025
  • Thumbnail for Pyruvate decarboxylase
    enzyme pyruvate dehydrogenase, an oxidoreductase (EC 1.2.4.1), that catalyzes the oxidative decarboxylation of pyruvate to acetyl-CoA. Pyruvate decarboxylase...
    9 KB (1,155 words) - 11:37, 3 June 2024
  • Thumbnail for Cellular respiration
    chains which later degrades into pyruvate.: 88–90  Pyruvate is oxidized to acetyl-CoA and CO2 by the pyruvate dehydrogenase complex (PDC). The PDC contains...
    31 KB (3,357 words) - 05:05, 1 July 2025
  • In enzymology, a pyruvate dehydrogenase (cytochrome) (EC 1.2.2.2) is an enzyme that catalyzes the chemical reaction pyruvate + ferricytochrome b1 + H2O...
    2 KB (189 words) - 17:11, 8 January 2025
  • The enzyme [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase (EC 3.1.3.43) catalyzes the reaction [pyruvate dehydrogenase (acetyl-transferring)]...
    2 KB (202 words) - 12:19, 26 August 2023
  • back reaction to produce NADH) pyruvate dehydrogenase (A common enzyme that feeds the TCA Cycle by converting pyruvate to acetyl CoA, using NAD+. In this...
    19 KB (2,153 words) - 12:57, 29 April 2025
  • This inhibition of glucose oxidation at the level of pyruvate dehydrogenase preserves pyruvate and lactate, both of which are gluconeogenic precursors...
    12 KB (1,520 words) - 12:39, 6 June 2025
  • Pyruvate dehydrogenase (NADP+) EC 1.2.1.51 is an enzyme that should not be confused with Pyruvate dehydrogenase (acetyltransferase) EC 1.2.4.1. It catalyzes...
    5 KB (526 words) - 15:39, 26 August 2023