Quantal neurotransmitter release is the process by which neurons communicate by releasing neurotransmitters in discrete, measurable units known as quanta...

Fatt that neurotransmitter release at synapses is "quantal", meaning that at any particular synapse, the amount of neurotransmitter released is never less...

revealing the quantal nature of synaptic transmission. Quantal size can then be defined as the synaptic response to the release of neurotransmitter from a single...

neurotransmitter storage, release, and inactivation. Their work included the discovery of the synaptic vesicle and quantal neurotransmitter release....

synaptic vesicles (or neurotransmitter vesicles) store various neurotransmitters that are released at the synapse. The release is regulated by a voltage-dependent...

(presynaptic) release probability pr, quantal size q (the postsynaptic response to the release of a single neurotransmitter vesicle, a 'quantum'), and n,...

disease. Also known as tetraplegia. Quantal neurotransmitter release The process by which neurotransmitters are released in discrete packets (quanta) from...

through") is the process by which signaling molecules called neurotransmitters are released by the axon terminal of a neuron (the presynaptic neuron), and...

chemical neurotransmission at the synapse. Neurotransmitters are packaged into synaptic vesicles for release from the presynaptic cell into the synapse...

they have smaller vesicles and quantal size, holding only an average of 1.9x10−19 moles of neurotransmitter released. The vesicles hold catecholamines...

fundamental "quantal" unit of neurotransmitter release from central synapses. They reported the first direct recordings of quantal neurotransmitter release from...

carrying neurotransmitters (mostly acetylcholine) are exocytosed and the contents are released into the neuromuscular junction. These neurotransmitters bind...

and most animals. In the brain, dopamine functions as a neurotransmitter—a chemical released by neurons (nerve cells) to send signals to other nerve cells...

monoamine releasing agent (MRA), or simply monoamine releaser, is a drug that induces the release of one or more monoamine neurotransmitters from the presynaptic...

membrane and subsequent neurotransmitter release from the motor neuron into the synaptic cleft. In vertebrates, motor neurons release acetylcholine (ACh)...

flux. Silent synapses were proposed as an explanation for differences in quantal content of excitatory postsynaptic currents (EPSCs) mediated by AMPARs...

house neurotransmitters in the synapse, generally produced by persistent high frequency neuronal stimulation. The neurotransmitters are released by the...

offered, including a lack of explanation for the probabilistic release of neurotransmitter from presynaptic axon terminals and an error in the calculated...

by synaptic vesicles carrying neurotransmitters. The sporadic nature of the release of quantal amounts of neurotransmitter led to the "vesicle hypothesis"...

time. These vesicles are large, consistent with the findings regarding quantal size in other adult synapses. Dense-core vesicles, usually containing neuropeptides...

pre-synaptic neurons release vesicles containing neurotransmitters into the synaptic cleft. The extracellular neurotransmitters then interact with particular...

mechanisms, such as quantal size adjustment, differential expression of presynaptic proteins, and modification of vesicle recycling. Quantal size adjustment...

students. In collaboration, they developed a quantum mechanical model of exocytosis and neurotransmitter release at synapses in the human cerebral cortex...

in the quantity of neurotransmitters released into a synapse and changes in how effectively cells respond to those neurotransmitters. Synaptic plasticity...

neuron is inhibitory, inhibitory neurotransmitters, normally GABA will be released into the synapse. This neurotransmitter causes an inhibitory postsynaptic...

vesicles store the neurotransmitter acetylcholine, providing a biochemical basis for the mechanism of quantal transmitter release. Based on earlier work...

trigger in transmitter release (co-author, 1978) Changes in total and quantal release of acetylcholine in the mouse diaphragm during activation and inhibiton...

docks and transiently fuses at the presynaptic membrane and releases its neurotransmitters across the synapse, after which the vesicle can then be reused...

the postsynaptic response varies based on the number of quanta released. Quantal release results in the inconsistent strength and timing of a response...

best known for his contributions in the field of non-quantal synaptic release of neurotransmitters. He graduated from the Faculty of Science of Charles...