RAD52 homolog (S. cerevisiae), also known as RAD52, is a protein which in humans is encoded by the RAD52 gene. The protein encoded by this gene shares...
24 KB (3,093 words) - 01:47, 19 February 2025
occur in succession without intervening diploid mitotic cell divisions. A RAD52 gene homolog from Kluyveromyces lactis was cloned and characterized. This...
3 KB (274 words) - 14:39, 4 October 2024
depends on BRCA1, PALB2 and BRCA2 while an alternative pathway depends on RAD52. Pre-clinical studies, involving epigenetically reduced or mutated BRCA-deficient...
26 KB (2,841 words) - 04:38, 24 May 2025
damaging chemicals. For instance, gene rad52 is required for both meiotic recombination and mitotic recombination. Rad52 mutants have increased sensitivity...
74 KB (8,616 words) - 08:44, 16 May 2025
the Acanthamoeba genome. These genes included Spo11, Mre11, Rad50, Rad51, Rad52, Mnd1, Dmc1, Msh and Mlh. This finding suggests that the ‘'Acanthamoeba'’...
51 KB (4,923 words) - 10:13, 25 May 2025
"A newly identified DNA ligase of Saccharomyces cerevisiae involved in RAD52-independent repair of DNA double-strand breaks". Genes & Development. 11...
81 KB (9,207 words) - 19:16, 31 May 2025
and RAD52 also coordinate in the heteroduplex formation, the RP-A protein has to be removed for the RAD51 to form the filament, whereas the RAD52 is a...
41 KB (5,013 words) - 02:11, 14 May 2025
protein can interact with the ssDNA-binding protein RPA, BRCA2, PALB2 and RAD52. The structural basis for Rad51 filament formation and its functional mechanism...
48 KB (5,526 words) - 19:40, 22 May 2025
Comeaux JC, Moyzis RK, Chen DJ (October 1996). "Associations of UBE2I with RAD52, UBL1, p53, and RAD51 proteins in a yeast two-hybrid system". Genomics....
131 KB (14,418 words) - 05:49, 1 June 2025
being a member of the evolutionarily conserved RAD52 epistasis group, which additionally includes RAD51, RAD52, RAD55, and RAD57 factors. This group is believed...
11 KB (1,444 words) - 13:16, 24 February 2024
mclk1 RAS2 akt-1/akt-2 PHB1 daf-16 PHB2 daf-12 CDC7 ctl-1 BUD1 old-1 RTG2 spe-26 RPD3 clk-1 HDA1 mev-1 SIR2 aak-2 SIR4-42 UTH4 YGL023 SGS1 RAD52 FOB1...
22 KB (2,844 words) - 17:49, 26 November 2024
"Structural basis for the recognition of DNA repair proteins UNG2, XPA, and RAD52 by replication factor RPA". Cell. 103 (3): 449–56. doi:10.1016/S0092-8674(00)00136-7...
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Larriba, Germán; Dubey, Dharani Dhar; Sanyal, Kaustuv (24 April 2014). "Rad51–Rad52 Mediated Maintenance of Centromeric Chromatin in Candida albicans". PLOS...
13 KB (1,106 words) - 15:48, 27 October 2024
genotoxic chemicals. For example, gene rad52 is required for mitotic recombination as well as meiotic recombination. Rad52 mutant yeast cells have increased...
12 KB (1,499 words) - 08:04, 5 October 2024
depends on BRCA1, PALB2 and BRCA2 while an alternative pathway depends on RAD52. Pre-clinical studies, involving epigenetically reduced or mutated BRCA-deficient...
66 KB (7,684 words) - 22:49, 25 April 2024
of sexual eukaryotes. These genes included Spo11, Mre11, Rad50, Rad51, Rad52, Mnd1, Dmc1, Msh and Mlh. This finding suggests that Acanthamoeba is capable...
45 KB (4,066 words) - 12:02, 12 April 2025
Nbs1), RAD51 and the ATM kinase. Further DNA repair components, such as RAD52 and RAD54, rapidly and reversibly interact with the core components stably...
22 KB (2,783 words) - 00:32, 30 May 2025
viable is due to the double-strand break repair genes RAD50, RAD51 and RAD52. The RAD27/FEN1 creates nicks between adjacent Okazaki fragments by minimizing...
34 KB (4,470 words) - 07:49, 11 November 2024
categories of response to DNA damage stimulus and DNA repair (such as RAD51, RAD52, and MRE11A), which are related to the adaptive traits of high infant birth...
52 KB (5,644 words) - 14:59, 14 April 2025
strands that were separated by heat (thermally denatured). Proteins such as RAD52 can help DNA anneal. DNA strand annealing is a key step in pathways of homologous...
24 KB (2,923 words) - 02:42, 25 January 2025
of sexual eukaryotes. These genes included Spo11, Mre11, Rad50, Rad51, Rad52, Mnd1, Dmc1, Msh, and Mlh. This finding suggests that Acanthamoeba is capable...
25 KB (2,845 words) - 07:59, 24 May 2025
may lead to MiDAS. Mitotic DNA synthesis is enabled by a protein known as RAD52, which then recruits enzymes, including MUS81 and POLD3. These enzymes work...
121 KB (14,916 words) - 04:06, 3 January 2025
prevents the 3' overhangs from sticking to themselves. A protein called Rad52 then binds each of the repeat sequences on either side of the break, and...
106 KB (12,117 words) - 22:03, 27 April 2025
Ward D, Lander ES (December 1994). "Large human YACs constructed in a rad52 strain show a reduced rate of chimerism". Genomics. 24 (3): 478–84. doi:10...
18 KB (1,982 words) - 02:50, 27 October 2024
S2CID 14249728. Coïc E, Feldman T, Landman AS, Haber JE (2008). "Mechanisms of Rad52-independent spontaneous and UV-induced mitotic recombination in Saccharomyces...
9 KB (1,265 words) - 11:50, 29 October 2024
deficient in DNA repair, exhibit a markedly different response. For instance, rad52 cells, which cannot repair double-stranded DNA breaks, tend to permanently...
81 KB (10,123 words) - 19:07, 23 May 2025
D-loop is formed by strand invasion with the help of proteins Rad51 and Rad52, and is then acted on by DNA helicase Srs2 to prevent formation of the double...
15 KB (1,822 words) - 03:57, 2 June 2025
Sung P, Lee EY (April 1999). "Radiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-Abl". J. Biol. Chem. 274 (18):...
30 KB (3,504 words) - 03:59, 7 April 2025
O15315 13357 RAD51C HGNC:9820 O43502 13358 RAD51D HGNC:9823 O75771 13359 RAD52 HGNC:9824 P43351 13360 RAD54B HGNC:17228 Q9Y620 13361 RAD54L HGNC:9826 Q92698...
282 KB (17 words) - 09:28, 10 February 2025
Song B, et al. (April 1999). "Radiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-Abl". The Journal of Biological...
50 KB (5,695 words) - 13:00, 26 February 2025