methods of RNA splicing occur in nature; the type of splicing depends on the structure of the spliced intron and the catalysts required for splicing to occur...
38 KB (4,660 words) - 16:36, 26 February 2025
Alternative splicing, alternative RNA splicing, or differential splicing, is an alternative splicing process during gene expression that allows a single...
62 KB (7,812 words) - 02:47, 17 February 2025
Small nuclear RNA (snRNA) is a class of small RNA molecules that are found within the splicing speckles and Cajal bodies of the cell nucleus in eukaryotic...
18 KB (2,335 words) - 16:05, 28 November 2024
Intron (category RNA splicing)
Exon mRNA Eukaryotic chromosome fine structure Small t intron Splicing: Alternative splicing Exitron Minor spliceosome Outron Function MicroRNA Others:...
47 KB (5,853 words) - 21:36, 25 April 2025
tRNAs. Whereas "normal" (cis-)splicing processes a single molecule, trans-splicing generates a single RNA transcript from multiple separate pre-mRNAs....
12 KB (1,369 words) - 12:07, 22 February 2024
process, RNA splicing removes the non-coding RNA introns leaving behind the exons, which are then spliced and joined together to form the mature mRNA. Splicing...
6 KB (596 words) - 20:39, 4 September 2024
chemical structure of the RNA molecule: the addition of a 5' cap, the addition of a 3' polyadenylated tail, and RNA splicing. Such processing is vital...
11 KB (1,432 words) - 23:35, 24 July 2024
process of RNA splicing, leaving only exons, regions that will encode the protein. This exon sequence constitutes mature mRNA. Mature mRNA is then read...
51 KB (6,206 words) - 17:35, 5 May 2025
Primary transcript (redirect from Heterogeneous nuclear RNA)
3'-polyadenylation, and alternative splicing. In particular, alternative splicing directly contributes to the diversity of mRNA found in cells. The modifications...
22 KB (2,668 words) - 08:52, 16 December 2024
Ribozyme (redirect from Catalytic RNA)
(ribonucleic acid enzymes) are RNA molecules that have the ability to catalyze specific biochemical reactions, including RNA splicing in gene expression, similar...
44 KB (5,382 words) - 17:57, 28 April 2025
Exon (category RNA splicing)
will form a part of the final mature RNA produced by that gene after introns have been removed by RNA splicing. The term exon refers to both the DNA...
13 KB (1,522 words) - 13:01, 21 April 2025
ZTTK syndrome (section Role of SON in RNA Splicing)
hESCs by ensuring genes undergo RNA splicing to create a mature RNA transcript. The SON gene is required for RNA splicing of transcripts encoding the cell-cycle...
25 KB (2,954 words) - 11:16, 11 May 2024
of Cis-acting RNA elements that influence exons inclusion or exclusion during splicing. These sites are referred to as exonic splicing enhancers (ESEs)...
39 KB (4,540 words) - 15:46, 4 November 2024
Spliceosome (category RNA splicing)
either sites of mRNA splicing or storage sites of mRNA splicing factors. It is now understood that nuclear speckles help concentrate splicing factors near...
22 KB (2,809 words) - 02:49, 20 November 2024
Cell nucleus (redirect from Splicing speckles)
organization of the gene-expression machinery splicing snRNPs and other splicing proteins necessary for pre-mRNA processing. Because of a cell's changing requirements...
88 KB (10,011 words) - 10:50, 11 May 2025
to be removed after transcription through a process termed RNA splicing. Splicing of RNA transcripts requires a highly precise and coordinated sequence...
42 KB (4,639 words) - 22:36, 1 April 2025
(ATP) or guanosine triphosphate (GTP). Normally, splicing is associated only with pre-mRNA splicing. This precursor protein contains three segments—an...
31 KB (3,821 words) - 22:43, 17 December 2023
the protein product. The spliceosome, a protein-RNA complex located in the nucleus, catalyzes splicing in the following manner: The spliceosome recognizes...
56 KB (6,708 words) - 20:49, 30 April 2025
generally not considered. (For that, see Proteoforms.) Through RNA splicing mechanisms, mRNA has the ability to select different protein-coding segments...
17 KB (2,010 words) - 02:30, 6 November 2024
BZIP intron plant (category RNA splicing)
R.; Rothstein, S. J.; Howell, S. H. (2011). "Heat induces the splicing by IRE1 of a mRNA encoding a transcription factor involved in the unfolded protein...
2 KB (229 words) - 14:03, 3 October 2021
SR protein (section Splicing)
alternative pre-mRNA splicing, mRNA export, genome stabilization, nonsense-mediated decay, and translation. SR proteins alternatively splice pre-mRNA by preferentially...
27 KB (3,443 words) - 03:57, 30 October 2024
an exonic splicing enhancer (ESE) is a DNA sequence motif consisting of 6 bases within an exon that directs, or enhances, accurate splicing of heterogeneous...
5 KB (596 words) - 19:24, 13 August 2023
alternative splicing is best seen in the sex determination of D. melanogaster. The Tra gene, determinant of sex, in male flies becomes truncated as splicing events...
17 KB (2,074 words) - 04:58, 29 October 2024
Zebrafish (section RNA splicing)
initiate RNA splicing. These genes have the DNA base pairs AC and TG as repeated sequences at the ends of each intron. On the 3'ss (3' splicing site), the...
113 KB (12,494 words) - 17:50, 17 May 2025
U2 snRNA has been theorized to serve a catalytic role in the chemistry of pre-RNA splicing as well. Similar to ribosomal RNAs (rRNAs), Sm snRNAs must...
15 KB (1,784 words) - 02:26, 23 September 2021
pre-mRNA, and various other proteins to assemble a spliceosome, a large RNA-protein molecular complex upon which splicing of pre-mRNA occurs. Splicing, or...
11 KB (1,314 words) - 17:41, 4 August 2024
mRNA transcripts, RNA-Seq can look at different populations of RNA to include total RNA, small RNA, such as miRNA, tRNA, and ribosomal profiling. RNA-Seq...
88 KB (9,465 words) - 02:10, 14 May 2025
Morpholino (section Modifying pre-mRNA splicing)
can also modify the splicing of pre-mRNA or inhibit the maturation and activity of miRNA. Techniques for targeting Morpholinos to RNAs and delivering Morpholinos...
37 KB (4,415 words) - 14:17, 28 August 2024
molecule. RNA editing is relatively rare, with common forms of RNA processing (e.g. splicing, 5'-capping, and 3'-polyadenylation) not usually considered...
61 KB (7,437 words) - 00:53, 7 March 2025
defective RNA. Splicing ribozymes catalyze RNA splicing, removing a section of RNA that contains a mutation and replacing it with well-functioning RNA. Existing...
6 KB (740 words) - 02:24, 6 August 2024