• Recombination signal sequences are conserved sequences of noncoding DNA that are recognized by the RAG1/RAG2 enzyme complex during V(D)J recombination...
    6 KB (663 words) - 10:52, 1 June 2023
  • To maintain the specificity of recombination, V(D)J recombinase recognizes and binds to recombination signal sequences (RSSs) flanking the variable (V)...
    21 KB (2,860 words) - 00:58, 15 January 2025
  • between the antigen receptor coding segment and a flanking recombination signal sequence (RSS). They do this in two steps. They initially introduce a...
    20 KB (2,422 words) - 23:24, 23 June 2025
  • statisticians in the UK Russell-Silver syndrome, a form of dwarfism Recombination signal sequences, genes used to generate antibodies and T-cell receptors in immunology...
    3 KB (390 words) - 15:34, 14 July 2025
  • sites, known as loxP sequences, contain specific binding sites for Cre that surround a directional core sequence where recombination can occur. When cells...
    40 KB (5,064 words) - 16:12, 17 July 2025
  • recombination of both alleles in highly expressed GATA3 cells. Vđť›˝ Recombination signal sequences (RSSs) with poor qualities suppressed one allele's expression...
    17 KB (1,896 words) - 21:21, 15 July 2025
  • Thumbnail for Non-homologous end joining
    created by the RAG1/RAG2 nuclease, which cleaves the DNA at recombination signal sequences. These hairpins are then opened by the Artemis nuclease and...
    29 KB (3,755 words) - 18:06, 16 July 2025
  • "The Recombination Hypothesis" is the 13th episode of the fifth season, as well as the 100th episode overall, of the American television sitcom The Big...
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  • Thumbnail for Illegitimate recombination
    Illegitimate recombination, or nonhomologous recombination, is the process by which two unrelated double stranded segments of DNA are joined. This insertion...
    8 KB (1,000 words) - 17:39, 3 December 2023
  • Uptake signal sequences (USS) are the short DNA sequences preferentially taken up by competent bacteria of the family Pasteurellaceae (e.g., Haemophilus...
    4 KB (424 words) - 07:09, 19 March 2025
  • an adapter molecule that binds to cellular sequence-specific DNA-binding proteins, JK recombination signal-binding protein (RBP-JK), and PU.1 as well...
    7 KB (896 words) - 09:15, 28 August 2021
  • Thumbnail for Homologous recombination
    homologous recombinational repair (HRR). Homologous recombination also produces new combinations of DNA sequences during meiosis, the process by which eukaryotes...
    106 KB (12,125 words) - 16:53, 17 July 2025
  • utilized in the system of homologous recombination to discern between similar DNA sequences. Homologous recombination facilitates the exchange of genetic...
    16 KB (1,702 words) - 11:28, 13 March 2023
  • During V(D)J recombination, the RAG complex (made up of RAG-1 and RAG-2 complexed with HMG1 or HMG2) binds to two recombination signal sequences (RSSs); the...
    3 KB (467 words) - 14:59, 15 March 2022
  • Thumbnail for Recombinant DNA
    methods of genetic recombination (such as molecular cloning) that bring together genetic material from multiple sources, creating sequences that would not...
    34 KB (3,852 words) - 13:16, 17 July 2025
  • Thumbnail for RAG1
    activity also requires RAG-2. The RAG-1/2 complex recognizes recombination signal sequences (RSSs) that flank the V, D and J regions in the genes that encode...
    13 KB (1,310 words) - 18:06, 17 July 2025
  • belcheri (Chinese lancelet). The TIRs are structurally similar to Recombination signal sequences (RSS). The heptamer bears the consensus CACWRTG, while the nonamer...
    4 KB (428 words) - 11:16, 9 June 2025
  • Thumbnail for RAG2
    phase during V(D)J recombination. This complex can make double-strand breaks by cleaving DNA at conserved recombination signal sequences (RSS). The other...
    9 KB (1,326 words) - 04:40, 15 July 2025
  • Thumbnail for DNA
    sequence, which then defines one or more protein sequences. The relationship between the nucleotide sequences of genes and the amino-acid sequences of...
    169 KB (18,029 words) - 13:44, 18 July 2025
  • Thumbnail for BRCA2
    recombination. Thus the BRC repeat sequences of BRCA2 appear to play a key role in recombinational repair of DNA damages during meiotic recombination...
    73 KB (7,913 words) - 01:52, 19 July 2025
  • long non-coding sequences in eukaryotic genes between the exons. The theory holds that the randomness of primordial DNA sequences would only permit...
    69 KB (8,036 words) - 01:15, 31 May 2025
  • Thumbnail for DNA shuffling
    are molecular breeding which relies on homologous recombination or the similarity of the DNA sequences, restriction enzymes which rely on common restriction...
    25 KB (2,913 words) - 01:20, 19 July 2025
  • Thumbnail for Retrovirus
    sites and sequences within their respective enzymes. However these drugs can quickly become ineffective due to the fact that the gene sequences that code...
    40 KB (4,565 words) - 03:56, 30 June 2025
  • Thumbnail for T-cell receptor
    T-cell receptor (category Cell signaling)
    arises mainly from genetic recombination of the DNA-encoded segments in individual somatic T cells by somatic V(D)J recombination using RAG1 and RAG2 recombinases...
    44 KB (5,378 words) - 07:54, 5 May 2025
  • occurs between specific sites on the DNA called recombination signal sequences (RSSs). The signal sequences are composed of a conserved palindromic heptamer...
    16 KB (2,077 words) - 17:27, 11 June 2025
  • Thumbnail for Bacterial conjugation
    that can integrate itself into the bacterial chromosome by homologous recombination) with a length of about 100 kb. It carries its own origin of replication...
    22 KB (2,419 words) - 16:37, 16 July 2025
  • Thumbnail for Diode
    platinum) acts as recombination centers, which helps the fast recombination of minority carriers. This allows the diode to operate at higher signal frequencies...
    64 KB (7,373 words) - 20:54, 27 June 2025
  • 2004). "Evidence for high specificity and efficiency of multiple recombination signals in mixed DNA cloning by the Multisite Gateway system". Journal of...
    61 KB (7,073 words) - 10:02, 24 June 2025
  • Thumbnail for RecA
    for sequence similarity along the dsDNA. A disordered DNA loop in RecA, Loop 2, contains the residues responsible for DNA homologous recombination. In...
    13 KB (1,426 words) - 02:38, 10 January 2025
  • Thumbnail for DNA repair protein XRCC4
    Recombination occurs in a specific region of the gene that is located between two conserved sequence motifs called recombination signal sequences. Each...
    43 KB (5,681 words) - 21:37, 15 July 2025