Skp, Cullin, F-box containing complex (or SCF complex) is a multi-protein E3 ubiquitin ligase complex that catalyzes the ubiquitination of proteins destined...

Look up SCF in Wiktionary, the free dictionary. SCF (or scf) may refer to: Saba Conservation Foundation, an NGO on the Caribbean island of Saba Sahara...

The first identified F-box protein is one of three components of the SCF complex, which mediates ubiquitination of proteins targeted for degradation by...

cullin genes CUL1, part of SCF complex CUL2, part of ECS complex (Elongin C - CUL2 - SOCS-box) CUL3, part of CUL3-BTB complex CUL4A CUL4B CUL5 CUL7 CUL9...

ligases such as the anaphase-promoting complex (APC) and the SCF complex (Skp1-Cullin-F-box protein complex). SCF complexes consist of four proteins: Rbx1, Cul1...

ubiquitination. This is an essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, which mediates the ubiquitination of proteins...

a complex with the kinesin-like protein Costal-2 (Cos2) and is localized in the cytoplasm bound to cellular microtubules (Figure 2). The SCF complex targets...

4) is a substrate recognition component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which acts as a mediator of ubiquitin transfer...

complex called SCFs (SKP1-cullin-F-box), which often—but not always—recognize substrates in a phosphorylation-dependent manner. In this SCF complex,...

protein family, which constitutes one of the four subunits in the SCF ubiquitin ligase complex. The FBXL3 protein participates in the negative feedback loop...

the substrate. The anaphase-promoting complex (APC) and the SCF complex (for Skp1-Cullin-F-box protein complex) are two examples of multi-subunit E3s...

by the anaphase promoting complex (APC), an E3 ubiquitin ligase. The APC and the Skp1/Cul1/F-box protein complex (SCF complex) are the two key regulators...

phosphorylates Wee1, targeting it for degradation through the SCF ubiquitin ligase complex (SCF complex), and activates Cdc25 through phosphorylation with combined...

proteasome. The APC/C is a large complex of 11–13 subunit proteins, including a cullin (Apc2) and RING (Apc11) subunit much like SCF. Other parts of the APC/C...

the E3 ubiquitin ligase SCFCOI1. The complexes that ultimately form are known as SCF complexes. These complexes bind JAZ and target it for proteasomal...

degraded via CUL1 (SCF complex), while FOXM1 is degraded during mitosis by the APC/C. Near the end of the cell cycle, the DREAM complex is re-assembled by...

activated complex will phosphorylate Sic1 at multiple sites which leads to its degradation by the SCF complex. When Sic1 is degraded, the Cdc28-Clb complex is...

together and held by the transposase in a Synaptic Complex Formation (SCF). The formation of the SCF is a checkpoint ensuring proper cleavage. HMGB1 is...

cell division cycle. These studies led his laboratory to discover the SCF complex SCFCdc4, which is the progenitor of what is now known to be a large family...

constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent...

thymocytes, cTECs provide cytokines, such as interleukin 7 (IL-7) and SCF complex, to promote early thymocyte progenitor (ETP) proliferation as well as...

draft. After being drafted, Alexander played for the rookie-level Florida Complex League Braves and Danville Braves, as well as the High-A Florida Fire Frogs...

to the interaction of Elk-1 to p38 MAPKs. Also, dimerization of the SCF complex facilitated by the D-domain shows insignificant overtly impact on catalytic...

(BRWD3) and SKP1-related A (SkpA). Jetlag proteins are members of the SCF complex (SKP1–Cullin1–F-box protein) family of ubiquitin ligases that controls...

divisions. Cyclin E at the fusome is phosphorylated for degradation by the SCF complex and if not degraded, an extra division occurs. The fusome may be the...

Conaway JW (Apr 1999). "Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase". Science. 284 (5414): 657–61. Bibcode:1999Sci...284...

Shi J, Luo L, Eash J, Ibebunjo C, Glass DJ (November 2011). "The SCF-Fbxo40 complex induces IRS1 ubiquitination in skeletal muscle, limiting IGF1 signaling"...

binds to unneddylated CUL1 and regulates the formation of SCF ubiquitin E3 ligase complex". Molecular Cell. 10 (6): 1519–26. doi:10.1016/S1097-2765(02)00784-0...

"Induction of APOBEC3G ubiquitination and degradation by an HIV-1 Vif-Cul5-SCF complex". Science. 302 (5647): 1056–60. Bibcode:2003Sci...302.1056Y. doi:10.1126/science...

gene. This gene encodes a protein that is a member of the SCF ubiquitin ligase protein complex. It binds to F-box proteins (proteins containing an F-box...