Terminal complement pathway deficiency is a genetic condition affecting the complement membrane attack complex (MAC). It involves deficiencies of C5, C6...

classical complement pathway is one of three pathways which activate the complement system, which is part of the immune system. The classical complement pathway...

C3/C4 values but a decreased CH50, that can indicate a terminal complement pathway deficiency while if one has low C3 and CH50 values that can indicate...

Neisseria have a thin cell wall and little to no glycocalyx. Terminal complement pathway deficiency Paroxysmal nocturnal haemoglobinuria Perforin Pore-forming...

lectin pathway or MBL pathway is a type of cascade reaction in the complement system, similar in structure to the classical complement pathway, in that...

biochemical pathways activate the complement system: the classical complement pathway, the alternative complement pathway, and the lectin pathway. The alternative...

in complement deficiencies.[medical citation needed] Among the possible complications are the following: Deficiencies of the terminal complement components...

classical complement pathway of the complement system. The antibodies IgM and all IgG subclasses except IgG4 are able to initiate the complement system....

insert into the phospholipid bilayer of the pathogen. Terminal complement pathway deficiency Complement+C7 at the U.S. National Library of Medicine Medical...

the complement system, acting as a multi-domain serine protease. Deficiency of C2 has been associated with certain autoimmune diseases. The Complement system...

the complement membrane attack complex. Deficiency is thought to cause Leiner's disease. Complement component 5 is the fifth component of complement, which...

TF, Zeitz HJ, Gewurz H (November 1980). "Inherited deficiency of the ninth component of complement in man". Journal of Immunology. 125 (5): 2252–7. doi:10...

Complement component 1s (EC 3.4.21.42, C1 esterase, activated complement C1s, complement C overbar 1r, C1s) is a protein involved in the complement system...

trypsin and the C1s subunit of the enzyme C1 involved in the classical complement pathway. Protease inactivation results as a consequence of trapping the protease...

blood cells by the complement system, a part of the body's innate immune system. This destructive process occurs due to deficiency of the red blood cell...

glycosylated, bearing both N- and O-glycans. N-terminal domain is especially heavily glycosylated. Deficiency of this protein is associated with hereditary...

Barone R, Blum L, Chase PH (1979). "Familial deficiency of two subunits of the first component of complement. C1r and C1s associated with a lupus erythematosus-like...

complement system subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of...

effects of the alternative pathway of complement. A rare functional coding change, p.R1210C, in CFH results in a functional deficiency in factor H and leads...

are the cause of nonspherocytic hemolytic anemia, and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological...

AH, Lachmann PJ, Walport MJ (September 1987). "Inherited deficiency of erythrocyte complement receptor type 1 does not cause susceptibility to systemic...

it is used to prevent and treat scurvy, a disease caused by vitamin C deficiency. Vitamin C is an essential nutrient involved in the repair of tissue,...

Innate immune system Complement system Classical complement pathway Mannan-binding lectin pathway Alternate complement pathway Complement membrane attack complex...

brain. Apo-E qualifies as a checkpoint inhibitor of the classical complement pathway by complex formation with activated C1q. Apolipoproteins are not unique...

phagocytes. The complement system can be activated through three pathways: the classical pathway, the alternative pathway, and the lectin pathway. One way the...

alternative complement pathway and also interferes with complement regulation by binding to complement factor H, an inhibitor of the complement cascade....

regulation, cellular transport, secretory processes and many other cellular pathways, which makes them very important to physiology. Kinases mediate the transfer...

Protein S exists in two forms: a free form and a complex form bound to complement protein C4b-binding protein (C4BP). In humans, protein S is encoded by...

Complement component 6 is a protein that in humans is encoded by the C6 gene. Complement component 6 is a protein involved in the complement system. It...

Griffin et al. first associated protein C deficiency with symptoms of venous thrombosis. Homozygous protein C deficiency and the consequent serious health effects...