In genomics, a genome-wide association study (GWA study, or GWAS), is an observational study of a genome-wide set of genetic variants in different individuals...

Transcriptome-wide association study (TWAS) is a genetic methodology that can be used to compare the genetic components of gene expression and the genetic...

An epigenome-wide association study (EWAS) is an examination of a genome-wide set of quantifiable epigenetic marks, such as DNA methylation, in different...

efficient ways of obtaining data about the transcriptome. Two biological techniques are used to study the transcriptome, namely DNA microarray, a hybridization-based...

A microbiome-wide association study (MWAS), otherwise known as a metagenome-wide association study (MGWAS), is a statistical methodology used to examine...

findings from genome-wide association studies. He has contributed to the development of the transcriptome-wide association study approach to mapping disease-associated...

cell-states change. Epigenome-wide association study Quantitative trait locus (QTL) Transcriptome-wide association study Rockman MV, Kruglyak L (November...

Shrestha, Subidhya; Solanki, Shyam; Brueggeman, Robert (2019). "Transcriptome-wide association study identifies putative elicitors/suppressor of Puccinia graminis...

providing a snapshot of gene expression in the sample, also known as transcriptome. RNA-Seq facilitates the ability to look at alternative gene spliced...

parts of the genome are expressed but also how they are spliced. Transcriptome-wide analysis of alternative splicing is typically performed by high-throughput...

Transcriptomics technologies are the techniques used to study an organism's transcriptome, the sum of all of its RNA transcripts. The information content...

of the transcriptome-wide association study (TWAS) methodology (PrediXcan), which integrates gene expression and genome-wide association study data to...

expression and gene structure on a genome-wide scope. They allow a new level of insight in studying the transcriptome and methylome. Drawbacks include the...

Masaki; Ohara, Osamu; Kubota, Shin (2016-08-01). "De Novo Assembly of the Transcriptome of Turritopsis, a Jellyfish that Repeatedly Rejuvenates". Zoological...

diseases or biological phenotypes. Epigenome-wide association study (EWAS) and transcriptome-wide association studies (TWAS) aim at finding the molecular markers...

trajectory inference. RNA-Seq Single-cell analysis Single-cell sequencing Transcriptome Transcriptomics Kanter, Itamar; Kalisky, Tomer (2015). "Single cell...

the genome, epigenome, transcriptome, proteome, metabolome, exposome, and microbiome (i.e., a meta-genome and/or meta-transcriptome, depending upon how it...

that allows for the investigation of phenotypes at the level of the transcriptome, to elucidate gene functions in many cells, in a massively parallel...

Manem V, Carreras-Torres R, Gabriel A, et al. (April 2020). "Transcriptome-wide association study reveals candidate causal genes for lung cancer". International...

sequencing. Libraries generated can be directly used for single cell whole transcriptome sequencing or target sequencing workflows. The sequencing is performed...

RNA-Seq is a technique that allows transcriptome studies (see also Transcriptomics technologies) based on next-generation sequencing technologies. This...

Genome-wide association studies (GWAS) identify linkages between alleles and observable traits such as phenotypes and diseases. Most of the associations are...

Bioinformatics List of omics topics in biology Plant Proteome Database Transcriptome Interactome Human Proteome Project BioPlex Human Protein Atlas Johnson...

Personalized Medicine. Snyder's research focuses on "omics", the study of genomes, transcriptomes, proteomes, and other high-throughput omics datasets. His lab...

correlations between the metabolome and the other cellular ensembles (genome, transcriptome, proteome, and lipidome), which can be used to predict metabolite abundances...

gene expression patterns in human cancer. These studies led Velculescu to coin the term transcriptome in a 1997 paper to describe the comprehensive gene...

enzyme that is a marker for cardiovascular risk identified by genome-wide association study. Protein recycling would be modulated by changes in the proteasomal...

variations, divergence between species and population structure. Genome-wide association studies (GWAS) are useful to examine the role of natural selection at the...

as an example of a protozoan and also as an example of symbiosis. A transcriptome sequence is determined. Moreover, a combination of long-read sequencing...

events on a genome wide scale. However, the precondition for large scale detection is a paired-end sequencing of the cell's transcriptome. The direction of...