• Thumbnail for Triosephosphate isomerase
    barrel Triose Phosphate Isomerase deficiency TPI1 Triosephosphate isomerase in interactive 3D at Proteopedia Triosephosphate isomerase (TIM) family in PROSITE...
    11 KB (1,178 words) - 19:15, 2 January 2025
  • Thumbnail for Triosephosphate isomerase deficiency
    Triosephosphate isomerase deficiency is a rare autosomal recessive metabolic disorder which was initially described in 1965. It is a unique glycolytic...
    5 KB (424 words) - 20:17, 29 October 2024
  • in 2500 to 3000 children born is affected by Cystic fibrosis. Triosephosphate isomerase (TPI) is a central enzyme of glycolysis, the main pathway for...
    24 KB (3,022 words) - 07:14, 10 February 2025
  • PMID 8244340. S2CID 3110178. "Triosephosphate Isomerase Deficiency". NORD. Retrieved 14 December 2013. "Triose phosphate isomerase deficiency -TPI" (PDF). Retrieved...
    37 KB (3,590 words) - 23:32, 29 January 2025
  • Thumbnail for Glycolysis
    aldolase Dihydroxyacetone phosphate + + Glyceraldehyde 3-phosphate Triosephosphate isomerase 2 × Glyceraldehyde 3-phosphate 2 ×  Glyceraldehyde-3-phosphate...
    82 KB (8,731 words) - 13:20, 26 April 2025
  • Thumbnail for TPI1
    Triosephosphate isomerase is an enzyme that in humans is encoded by the TPI1 gene. This gene encodes an enzyme, consisting of two identical proteins,...
    16 KB (2,072 words) - 03:51, 29 July 2024
  • Thumbnail for Glycerol
    dehydrogenase NAD+ NADH NAD+ NADH Dihydroxyacetone phosphate Triosephosphate isomerase Glyceraldehyde 3-phosphate The enzyme glycerol kinase is present...
    52 KB (5,009 words) - 10:48, 8 May 2025
  • Thumbnail for Ribose 5-phosphate
    synthesize NADPH and R5P. This process is further enabled by triosephosphate isomerase inhibition by phosphoenolpyruvate, the PKM substrate. R5P and...
    15 KB (1,499 words) - 18:07, 29 August 2024
  • as T-cell immunoglobulin and mucin-domain containing-3 (TIM-3) Triosephosphate isomerase TIM (psychedelics) (thioisomescaline), a series of psychedelic...
    4 KB (489 words) - 13:02, 1 February 2025
  • Thumbnail for TIM barrel
    folding design that adopted its intended structure. Protein folding Triosephosphate isomerase This article was adapted from the following source under a CC...
    46 KB (4,821 words) - 15:00, 14 March 2025
  • Thumbnail for Enzyme kinetics
    another, and isomerase is a more general term for an enzyme that catalyses any one-substrate one-product reaction, such as triosephosphate isomerase. However...
    72 KB (9,551 words) - 07:46, 27 March 2025
  • Thumbnail for 2-Dehydro-3-deoxy-phosphogluconate aldolase
    hydrophobic interactions. The molecule has tertiary folding similar to triosephosphate isomerase and the A-domain of pyruvate kinase, forming an eight strand α/β-barrel...
    14 KB (1,633 words) - 18:25, 10 May 2025
  • Thumbnail for Glyceraldehyde
    dihydroxyacetone (dihydroxyacetone phosphate), catalyzed by the enzyme triosephosphate isomerase, is an intermediate step in glycolysis. Stereoisomerism https://iupac...
    10 KB (700 words) - 20:17, 11 May 2025
  • Thumbnail for Air pollution in Delhi
    1975). "The influence of pH on the interaction of inhibitors with triosephosphate isomerase and determination of the pKa of the active-site carboxyl group"...
    57 KB (5,671 words) - 17:10, 2 May 2025
  • Thumbnail for Fructose
    DHAP can either be isomerized to glyceraldehyde 3-phosphate by triosephosphate isomerase or undergo reduction to glycerol 3-phosphate by glycerol 3-phosphate...
    52 KB (5,305 words) - 21:17, 7 May 2025
  • Thumbnail for CD4
    et al. (April 1996). "A gene-rich cluster between the CD4 and triosephosphate isomerase genes at human chromosome 12p13". Genome Research. 6 (4): 314–326...
    22 KB (2,581 words) - 20:03, 21 June 2024
  • Thumbnail for Inborn errors of carbohydrate metabolism
    weakness and cramping. Glucose-6-phosphate isomerase deficiency affects step 2 of glycolysis. Triosephosphate isomerase deficiency affects step 5 of glycolysis...
    59 KB (2,814 words) - 08:33, 2 May 2025
  • (glpF), guanylate kinase (gmk), phosphate acetyltransferase (pta), triosephosphate isomerase (tpi) and acetyl coenzyme A acetyltransferase (yqiL) as specified...
    27 KB (3,452 words) - 02:22, 3 December 2023
  • deficiency Trimethadione antenatal infection Trimethylaminuria Triopia Triosephosphate isomerase deficiency Triphalangeal thumb non opposable Triphalangeal thumb...
    10 KB (852 words) - 10:20, 12 May 2025
  • DHAP can either be isomerized to glyceraldehyde 3-phosphate by triosephosphate isomerase or undergo reduction to glycerol 3-phosphate by glycerol 3-phosphate...
    18 KB (1,917 words) - 15:54, 9 January 2025
  • Thumbnail for Phospholipase C
    domains specific to each family. The core enzyme includes a split triosephosphate isomerase (TIM) barrel, pleckstrin homology (PH) domain, four tandem EF...
    25 KB (2,691 words) - 16:58, 4 May 2025
  • guidance of David Chilton Phillips working on the structure of the triosephosphate isomerase. He then did postdoctoral research at Harvard University with...
    7 KB (565 words) - 19:12, 24 March 2025
  • Thumbnail for Irwin Rose
    PMID 14493830. Rose, Irwin A.; Rieder, S. V. (1959). "Mechanism of the triosephosphate isomerase reaction". J. Biol. Chem. 234 (5): 1007–1010. doi:10.1016/S0021-9258(18)98120-2...
    15 KB (1,351 words) - 18:25, 20 April 2025
  • Thumbnail for Gregory Petsko
    Phillips, studying the structure and mechanism of the enzyme triosephosphate isomerase. [1] He did a brief postdoctoral fellowship in Paris with Pierre...
    19 KB (1,744 words) - 01:08, 1 February 2025
  • Thumbnail for Shellfish allergy
    are widely present across shellfish species. Troponin, actin, triosephosphate isomerase and hemocyanin are also identified as allergenic proteins. As...
    41 KB (4,646 words) - 18:14, 2 March 2025
  • Thumbnail for Peripheral membrane protein
    diacylglycerol. Lipid signaling core structure composed of a split triosephosphate isomerase (TIM) barrel which has an active site, catalytic residues, and...
    54 KB (4,414 words) - 13:09, 9 December 2024
  • Thumbnail for Glycerol-3-phosphate dehydrogenase
    aldolase, splitting the C6-molecule into two triose phosphates (C) triosephosphate isomerase, interconverting DHAP and GAP. (D) glycerol pathway reducing DHAP...
    23 KB (2,206 words) - 08:06, 8 October 2024
  • Lehrach, Hans; Krobitsch, Sylvia (December 20, 2006). "Triose Phosphate Isomerase Deficiency Is Caused by Altered Dimerization–Not Catalytic Inactivity–of...
    70 KB (2,600 words) - 22:36, 22 December 2024
  • Thumbnail for Phosphopentose epimerase
    solution. Furthermore, Phosphopentose epimerase folds into a (β/α)8 triosephosphate isomerase (TIM) barrel that includes loops. The core barrel is composed...
    16 KB (1,880 words) - 06:51, 3 November 2024
  • A. R.; Esnouf, M. P. (1972). "Preparation and properties of triosephosphate isomerase from chicken muscle and a comparison with that from rabbit muscle"...
    25 KB (2,416 words) - 16:53, 1 December 2024