3-O-Methyldopa (3-OMD) is one of the most important metabolites of L-DOPA, a drug used in the treatment of the Parkinson's disease. 3-O-methyldopa is produced...

inhibitor is based on its ability to prevent the methylation of levodopa to 3-O-methyldopa, thus increasing the bioavailability of levodopa. COMT inhibitors significantly...

Methyldopa, sold under the brand name Aldomet among others, is a medication used for high blood pressure. It is one of the preferred treatments for high...

(AADC). l-DOPA can be directly metabolized by catechol-O-methyl transferase to 3-O-methyldopa, and then further to vanillactic acid. This metabolic pathway...

affecting facial muscles Oromandibular dystonia, neurological disease 3-O-Methyldopa, metabolite and drug Occult macular dystrophy, a rare genetic retinal...

PMID 9361073. Hornykiewicz O (2002). "L-DOPA: from a biologically inactive amino acid to a successful therapeutic agent". Amino Acids. 23 (1–3): 65–70. doi:10...

The molecular formula C10H13NO4 may refer to: Farinomalein Methyldopa 3-O-Methyldopa Melevodopa This set index page lists chemical structure articles...

controlled comparative studies versus clonidine (0.15 to 0.30 mg/day) or alpha-methyldopa (500 to 1000 mg/day) demonstrated that the incidence of side effects was...

 328–331. ISBN 0313291705. "Careers". The Phoenix of Alpha Sigma Alpha (3): 3. Spring 1978. Retrieved 5 September 2020. "[Nansie Sue Sharpless]". Detroit...

4-dimethoxybenzaldehyde affords the precursor to the antihypertensive drug methyldopa; condensation with unsubstituted benzaldehyde yields phenyl-2-nitropropene...

levodopa. It thereby prevents the 3-O-methylation of levodopa by COMT in the periphery, which produces 3-O-methyldopa, a major metabolite that competes...

levels in the body, with drugs being metabolized by COMT (for example methyldopa, dobutamine, apomorphine, adrenaline, and isoprenaline), with iron because...

Catechol-O-methyltransferase (COMT; EC 2.1.1.6) is one of several enzymes that degrade catecholamines (neurotransmitters such as dopamine, epinephrine...

treat hypertension in pregnancy, though, with either labetalol and/or methyldopa. Hydralazine is commonly used in combination with isosorbide dinitrate...

6-Fluoronorepinephrine Indanidine Levonordefrin Metaraminol Methoxamine Methyldopa Midodrine Naphazoline Norepinephrine (noradrenaline) Octopamine Oxymetazoline...

swelling. Phentermine may decrease the effect of drugs like clonidine, methyldopa, and guanethidine. Drugs to treat hypothyroidism may increase the effect...

Meciadanol is a synthetic O-methylated flavanol. It is the 3-O-methylation of catechin. It inhibits histidine decarboxylase in rats. Konturek, Stanislaw...

known as 3-hydroxyphenylalanine, L-m-tyrosine, and m-tyr) and ortho-tyrosine (o-tyr or 2-hydroxyphenylalanine), that occur in nature. The m-tyr and o-tyr isomers...

Norfenefrine (INN; also known as meta-octopamine, 3-octopamine, and 3,β-dihydroxyphenethylamine) is an adrenergic agent used as a sympathomimetic drug...

resulting in its relaxation. Mirabegron is the first clinically available beta-3 agonist with approval for use in adults with overactive bladder. Mirabegron...

4-Dihydroxystyrene 3-Iodotyrosine • Aquayamycin • Bulbocapnine • Metirosine • Oudenone Benserazide • Carbidopa • Genistein • Methyldopa Nonselective: Benmoxin •...

blocker Clonidine (α-receptor agonist, α2 > α1, giving negative feedback) Methyldopa (α2 agonist, giving negative feedback) Propranolol (β-receptor antagonist)...

of alpha-methyldopa: regional levels of endogenous and alpha-methylated catecholamines in rat brain". European Journal of Pharmacology. 52 (3–4): 271–80...

about 1 to 2 hours after a dose of midodrine and has a half-life of about 3 to 4 hours. The absolute bioavailability of midodrine (measured as desglymidodrine)...

However, the 4-hydroxy group makes it susceptible to metabolism by catechol-O-methyl transferase (COMT). Since it is β2-selective it is used for premature...

dizziness (11%) Gastrointestinal: nausea (6%), dyspepsia (3%) Cholinergic: nasal congestion (3%), ejaculation failure (2%) Respiratory: dyspnea (2%) Other:...

ring, the molecule is less susceptible to metabolism by the enzyme catechol-O-methyl transferase. Terbutaline is synthesized by brominating 3,5-dibenzyloxyacetophenone...

4-dihydroxyphenylalanine (DFMD, DFM-DOPA) is a DOPA decarboxylase inhibitor. Carbidopa Methyldopa Zbinden G, Brändle E (February 1980). "Inhibition of 5-hydroxytryptophan...

3-Iodotyrosine is an intermediate in the synthesis of thyroid hormones which is derived from iodination of tyrosine at the meta-position of the benzene...

Haibach O, Dermietzel R (2006). Neurotransmitters and Neuromodulators: Handbook of Receptors and Biological Effects. Wiley-VCH. p. 125. ISBN 978-3-527-31307-5...