5-hydroxytryptamine (serotonin) 1E receptor (5-HT1E) is a highly expressed human G-protein coupled receptor that belongs to the 5-HT1 receptor family (Gi-coupled...
9 KB (1,202 words) - 15:59, 22 May 2025
5-HT receptors, 5-hydroxytryptamine receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in...
65 KB (5,273 words) - 08:55, 28 May 2025
triptan eletriptan is an agonist of the 5-HT1E receptor. BRL-54443 is a selective 5-HT1E and 5-HT1F receptor agonist which is used in scientific research...
16 KB (1,664 words) - 07:32, 20 February 2025
The 5-HT2C receptor is a subtype of the 5-HT2 receptor that binds the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5-HT). Like all 5-HT2...
51 KB (6,133 words) - 17:35, 28 May 2025
5-n-Butyryloxy-DMT: >60-fold selectivity versus 5-HT1E receptor BRL-54443 - mixed 5-HT1E/1F agonist Eletriptan - mixed 5-HT1B/1D/1E/1F/2B/7 agonist LY-334,370 -...
9 KB (1,053 words) - 16:05, 22 May 2025
functionally from all other 5-HT receptors (5-hydroxytryptamine, or serotonin receptors) which are G protein-coupled receptors. This ion channel is cation-selective...
23 KB (2,440 words) - 22:20, 30 May 2025
The 5HT6 receptor is a subtype of 5HT receptor that binds the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5HT). It is a G protein-coupled...
29 KB (3,306 words) - 05:19, 25 May 2025
5-HT2A receptor 5-HT2B receptor 5-HT2C receptor 5-HT1 receptor 5-HT3 receptor 5-HT4 receptor 5-HT5 receptor 5-HT6 receptor 5-HT7 receptor Category:5-HT2...
2 KB (166 words) - 00:47, 13 May 2022
206 nM affinity. SB-699,551 5-HT receptor 5-HT1 receptor 5-HT2 receptor 5-HT3 receptor 5-HT4 receptor 5-HT6 receptor 5-HT7 receptor GRCh38: Ensembl release...
16 KB (1,773 words) - 06:08, 29 April 2025
5-hydroxytryptamine (serotonin) receptor 1D, also known as HTR1D, is a 5-HT receptor, but also denotes the human gene encoding it. 5-HT1D acts on the central...
11 KB (1,241 words) - 12:55, 30 May 2025
including 5-HT1A, 5-HT1B, 5-HT1D, 5-HT1E, and 5-HT1F. Receptors of the 5-HT1 type, specifically, the 5-HT1A and 5-HT1D receptor subtypes, are present on...
5 KB (472 words) - 15:42, 23 May 2025
receptor (or 5-HT1A receptor) is a subtype of serotonin receptors, or 5-HT receptors, that binds serotonin, also known as 5-HT, a neurotransmitter. 5-HT1A...
59 KB (6,182 words) - 23:06, 22 May 2025
The 5-HT2A receptor is a subtype of the 5-HT2 receptor that belongs to the serotonin receptor family and functions as a G protein-coupled receptor (GPCR)...
131 KB (13,676 words) - 19:49, 29 May 2025
that is strongly correlated with the expression of 5-HT1E. Outside of the CNS, the 5-HT1B receptor is also expressed on the endothelium of blood vessels...
23 KB (2,513 words) - 10:28, 14 April 2025
The 5-HT3 antagonists, informally known as "setrons", are a class of drugs that act as receptor antagonists at the 5-HT3 receptor, a subtype of serotonin...
43 KB (4,637 words) - 19:49, 29 May 2025
JPC0323 (category 5-HT2A receptor positive allosteric modulators)
3-dihydroxy-2-(hydroxymethyl)propan-2-yl)oleamide, is a dual serotonin 5-HT2C and 5-HT2A receptor positive allosteric modulator related to oleamide. It showed negligible...
6 KB (427 words) - 17:28, 28 May 2025
μ, δ1, δ2, κ Serotonergic: 5-HT1A, 5-HT1B, 5-HT1D, 5-HT1E, 5-HT1F, 5-HT2A, 5-HT2B, 5-HT2C, 5-HT3, 5-HT4, 5-HT5, 5-HT6, 5-HT7 Autoreceptor Catecholamines...
16 KB (1,590 words) - 11:48, 27 December 2024
5-HT2C receptor agonists are a class of drugs that activate 5-HT2C receptors. They have been investigated for the treatment of a number of conditions including...
49 KB (5,040 words) - 19:49, 29 May 2025
5-MeO-NiPT, also known as 5-methoxy-N-isopropyltryptamine, is a serotonin receptor agonist and serotonergic psychedelic of the tryptamine family. It was...
6 KB (439 words) - 09:29, 31 May 2025
000-fold higher affinity for the serotonin 5-HT1A receptor over the serotonin 5-HT2A receptor. In relation to this, 5-MeO-DMT has been described as an "atypical"...
72 KB (6,244 words) - 03:32, 3 June 2025
JRT (drug) (category Serotonin receptor modulators)
serotonin receptors and does not bind to various dopamine, adrenergic, or histamine receptors. (+)-JRT shows high affinity for the serotonin 5-HT2 receptors, with...
11 KB (830 words) - 05:27, 23 May 2025
5-Hydroxytryptamine receptor 2B (5-HT2B) also known as serotonin receptor 2B is a protein that in humans is encoded by the HTR2B gene. 5-HT2B is a member...
82 KB (7,913 words) - 17:32, 28 May 2025
BRL-54443 (category 5-HT1E agonists)
BRL-54443 is a drug which acts as a selective agonist for the 5-HT1E and 5-HT1F serotonin receptor subtypes. CP-94253 RS134-49 RU-24969 Sertindole SN-22 VU6067416...
2 KB (110 words) - 16:36, 18 March 2025
CTW0415 (category 5-HT2C receptor positive allosteric modulators)
family, which acts as a selective positive allosteric modulator of the 5-HT2C receptor, with higher potency than older drugs such as VA012. Structure-activity...
3 KB (223 words) - 08:28, 30 May 2025
1-(1-Naphthyl)piperazine (category Serotonin receptor antagonists)
partial agonism at the 5-HT1A, 5-HT1B, 5-HT1D, 5-HT1E, and 5-HT1F receptors, while antagonizing the 5-HT2A, 5-HT2B, and 5-HT2C receptors. It has also been...
11 KB (971 words) - 03:15, 27 May 2025
ASR-3001 (redirect from 5-methoxy-N-allyl-N-isopropyltryptamine)
known as 5-methoxy-N-allyl-N-isopropyltryptamine (5-MeO-iPALT), is a serotonin receptor agonist and serotonergic psychedelic of the tryptamine and 5-methoxytryptamine...
9 KB (730 words) - 04:21, 19 May 2025
identified as 5-MeO-AMT. 5-MeO-AMT acts as a non-selective serotonin receptor agonist, including of the serotonin 5-HT1A, 5-HT2A, and 5-HT2B receptors, among...
34 KB (2,826 words) - 21:47, 26 May 2025
ASR-2001 (redirect from 5-PrO-2C-B)
known as 2CB-5PrO or as 4-bromo-2-methoxy-5-propoxyphenethylamine, is a non-hallucinogenic serotonin receptor agonist agonist of the phenethylamine, 2C...
10 KB (809 words) - 04:35, 19 May 2025
Chamomile (ethanol extract) 5-HT receptor 5-HT1 receptor 5-HT2 receptor 5-HT3 receptor 5-HT5 receptor 5-HT6 receptor 5-HT7 receptor GRCh38: Ensembl release...
18 KB (2,096 words) - 04:06, 20 May 2025
release, 249 nM (EmaxTooltip maximal efficacy = 87%) for serotonin 5-HT2A receptor agonism (7.5-fold lower than for serotonin release), 1,838 nM for dopamine...
5 KB (443 words) - 14:38, 2 May 2025