A circulating tumor cell (CTC) is a cancer cell from a primary tumor that has shed into the blood of the circulatory system, or the lymph of the lymphatic...
67 KB (7,842 words) - 22:18, 20 May 2025
Circulating tumor DNA (ctDNA) is tumor-derived fragmented DNA in the bloodstream that is not associated with cells. ctDNA should not be confused with cell-free...
50 KB (5,935 words) - 10:18, 24 May 2025
Metastasis (redirect from Metastatic tumor)
Some cancer cells, known as circulating tumor cells (CTCs), are able to penetrate the walls of lymphatic or blood vessels, and circulate through the bloodstream...
42 KB (5,069 words) - 04:19, 14 May 2025
of cell-free circulating tumor DNA (cfDNA) has an advantage over circulating tumor cells assays in that there is approximately 100 times more cell-free...
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Invasion (cancer) (redirect from Tumor invasion)
patterns of cancer cell invasion by cell migration: collective cell migration and individual cell migration, by which tumor cells overcome barriers of...
46 KB (6,026 words) - 16:01, 26 September 2024
The cancer exodus hypothesis establishes that circulating tumor cell clusters (CTC clusters) maintain their multicellular structure throughout the metastatic...
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2014). "Circulating Tumor Cell Clusters Are Oligoclonal Precursors of Breast Cancer Metastasis". Cell. 158 (5): 1110–1122. doi:10.1016/j.cell.2014.07...
37 KB (4,314 words) - 12:20, 23 May 2025
Microvesicle (redirect from Circulating microvesicle)
inhibits T-cell proliferation and prevents the removal of circulating tumor cells (CTCs). As a consequence, tumor cells can turn off T-cell responses or...
54 KB (6,074 words) - 21:14, 22 May 2025
2019). "Circulating Tumor Cell Clustering Shapes DNA Methylation to Enable Metastasis Seeding". Cell. 176 (1–2): 98–112.e14. doi:10.1016/j.cell.2018.11...
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structures, especially exosomes, and, in the context of cancer, circulating tumor cells. There are several types of liquid biopsy methods; method selection...
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tumor, cancer cells circulate throughout the body. They are known as circulating tumor cells once they are in the blood. Few circulating tumor cells can disseminate to...
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company founded in 2008, offering medical diagnostics characterizing circulating tumor cells. Its technology is licensed from Scripps Research Institute, based...
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Norton, L; Massagué, J (2009). "Tumor self-seeding by circulating cancer cells". Cell. 139 (7): 1315–26. doi:10.1016/j.cell.2009.11.025. PMC 2810531. PMID 20064377...
53 KB (5,955 words) - 16:03, 30 March 2024
Drosophila embryos), in the entire tissue (whole mount ISH), in cells, and in circulating tumor cells (CTCs). This is distinct from immunohistochemistry, which...
12 KB (1,319 words) - 22:05, 23 May 2025
forms of DNA freely circulating in body fluids, including circulating tumor DNA (ctDNA), cell-free mitochondrial DNA (ccf mtDNA), cell-free fetal DNA (cffDNA)...
37 KB (4,221 words) - 23:00, 24 May 2025
is useful for expanded use of rare samples e.g.: stem cells, biopsies, circulating tumor cells. The reaction involves thermal cycling of the DNA sequence...
93 KB (9,857 words) - 07:17, 13 August 2024
Circulating mitochondrial DNA, also called cell-free circulating mitochondrial DNA and circulating cell-free mitochondrial DNA (ccf mtDNA), are short...
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CAPP-Seq (section Monitoring tumor burden)
The use of ctDNA in this technique should not be confused with circulating tumor cells (CTCs); these are two different entities. Originally described...
22 KB (2,809 words) - 14:27, 17 December 2024
Methods for Circulating Tumor Cell Isolation and Molecular Analysis". Isolation and Molecular Characterization of Circulating Tumor Cells. Advances in...
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but less aggressive tumors composed of more mature neural cells include ganglioneuroblastoma and ganglioneuroma. Neuroblastic tumors often produce elevated...
38 KB (3,928 words) - 21:04, 22 May 2025
solid tumor biopsy. This is simply a blood draw that contains circulating tumor cells (CTCs) which are shed into the bloodstream from solid tumors. Patients...
61 KB (6,861 words) - 22:48, 22 May 2025
The tumor microenvironment is a complex ecosystem surrounding a tumor, composed of cancer cells, stromal tissue (including blood vessels, immune cells, fibroblasts...
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Biomarker (medicine) (redirect from Biomarker (cell))
Velculescu VE (June 2014). "Blood-based analyses of cancer: circulating tumor cells and circulating tumor DNA". Cancer Discovery. 4 (6): 650–661. doi:10.1158/2159-8290...
57 KB (7,099 words) - 10:52, 5 April 2025
therapy). The CAR programs the T cells to target an antigen present on the tumor cell surface. For safety, CAR T cells are engineered to be specific to...
90 KB (9,260 words) - 17:32, 23 May 2025
cells, circulating tumor cells, and tissue samples. In this context, it can help define the spatial-temporal patterns of gene expression within cells...
39 KB (4,596 words) - 20:24, 12 May 2025
induces inflammation by binding to its receptors on other cells. It is a member of the tumor necrosis factor superfamily, a family of transmembrane proteins...
49 KB (6,227 words) - 17:23, 29 April 2025
lymphoid cells (ILC) and represent 5–20% of all circulating lymphocytes in humans. The role of NK cells is analogous to that of cytotoxic T cells in the...
75 KB (9,229 words) - 15:59, 25 May 2025
for cell isolation. Cell-types often of interest to purify may be specific leukocytes, such as CD4+ T cells, stem cells, or circulating tumor cells (CTCs)...
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halomethane Centralized traffic control, a form of railway signalling Circulating tumor cell, in the blood Closed timelike curve, in general relativity Common...
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Angiopellosis (category Cell movement)
that stem cells reach damaged tissue when injected or infused into the circulatory system. It has been found that circulating tumor cells (CTCs) possess...
11 KB (1,237 words) - 10:04, 3 February 2025