• Thumbnail for Colony stimulating factor 1 receptor
    Colony stimulating factor 1 receptor (CSF1R), also known as macrophage colony-stimulating factor receptor (M-CSFR), and CD115 (Cluster of Differentiation...
    44 KB (4,600 words) - 20:25, 29 May 2025
  • Thumbnail for Macrophage colony-stimulating factor
    the three experimentally described colony-stimulating factors. M-CSF binds to the colony stimulating factor 1 receptor. It may also be involved in development...
    17 KB (2,039 words) - 09:18, 2 May 2025
  • Thumbnail for Granulocyte colony-stimulating factor
    Granulocyte colony-stimulating factor (G-CSF or GCSF), also known as colony-stimulating factor 3 (CSF 3), is a glycoprotein that stimulates the bone marrow...
    33 KB (3,830 words) - 21:00, 29 May 2025
  • Thumbnail for Granulocyte-macrophage colony-stimulating factor
    Granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony-stimulating factor 2 (CSF2), is a monomeric glycoprotein secreted by macrophages...
    17 KB (1,680 words) - 21:00, 29 May 2025
  • Thumbnail for Granulocyte colony-stimulating factor receptor
    The granulocyte colony-stimulating factor receptor (G-CSF-R) also known as CD114 (Cluster of Differentiation 114) is a protein that in humans is encoded...
    13 KB (1,548 words) - 05:32, 17 August 2024
  • Colony-stimulating factors (CSFs) are secreted glycoproteins that bind to receptor proteins on the surfaces of committed progenitors in the bone marrow...
    3 KB (374 words) - 18:45, 17 July 2023
  • Thumbnail for Granulocyte-macrophage colony-stimulating factor receptor
    colony-stimulating factor receptor, also known as CD116 (Cluster of Differentiation 116), is a receptor for granulocyte-macrophage colony-stimulating...
    22 KB (2,709 words) - 04:21, 13 August 2024
  • Colony-stimulating factors Macrophage colony-stimulating factor (M-CSF) Granulocyte colony-stimulating factor (G-CSF) Granulocyte macrophage colony-stimulating...
    10 KB (1,131 words) - 18:45, 6 May 2025
  • Thumbnail for Osteoporosis
    activation of colony stimulating factor 1 receptor (CSF1R). Menopause-associated increase production of TNF-α stimulates stromal cells to produce colony stimulating...
    142 KB (16,131 words) - 09:17, 22 June 2025
  • Thumbnail for Tenosynovial giant cell tumor
    grow due to genetic overexpression of colony stimulating factor 1. This causes colony-stimulating factor-1 receptor (CSF1R) cells to accumulate in the joint...
    30 KB (2,394 words) - 22:20, 29 May 2025
  • chronic graft-versus-host disease. It is a blocker of the colony stimulating factor-1 receptor. It is given by injection into a vein. Axatilimab was approved...
    7 KB (391 words) - 20:04, 29 May 2025
  • Thumbnail for Hereditary diffuse leukoencephalopathy with spheroids
    of HDLS in most families is mutation in the colony stimulating factor 1 receptor (CSF1R), a growth factor for microglia and monocyte/macrophages, suggesting...
    18 KB (2,136 words) - 12:39, 16 May 2025
  • Thumbnail for Pimicotinib
    highly potent and selective small molecule blocker of the colony-stimulating factor 1 receptor (CSF-1R) independently discovered by Abbisko Therapeutics...
    6 KB (486 words) - 16:05, 19 September 2024
  • macrophage colony-stimulating factor (M-CSF), granulocyte-macrophage colony-stimulating factor (GM-CSF), and neurotactin. "Neurotrophic factors". Nature...
    16 KB (1,784 words) - 04:08, 6 January 2024
  • Thumbnail for Epidermal growth factor receptor
    growth factor receptor (EGFR; ErbB-1; HER1 in humans) is a transmembrane protein that is a receptor for members of the epidermal growth factor family...
    60 KB (6,879 words) - 01:06, 1 March 2025
  • Thumbnail for Osteoclast
    acts through its receptor on the osteoclast, c-fms (colony-stimulating factor 1 receptor), a transmembrane tyrosine kinase-receptor, leading to secondary...
    25 KB (2,908 words) - 23:33, 8 May 2025
  • Thumbnail for Immunoglobulin superfamily
    Immunoglobulin superfamily (category Receptors)
    domain or fold. Members of the IgSF include cell surface antigen receptors, co-receptors and co-stimulatory molecules of the immune system, molecules involved...
    16 KB (847 words) - 16:32, 9 September 2024
  • interleukin receptors, colony stimulating factor receptors and other cytokine receptors Interleukin-1 receptor Interleukin-2 receptor Interleukin-3 receptor Interleukin-4...
    5 KB (515 words) - 16:54, 21 June 2025
  • Thumbnail for Insulin-like growth factor
    distinct tissue types express the IGF-1 receptor, IGF-1's effects are diverse. It acts as a neurotrophic factor, inducing the survival of neurons. It...
    14 KB (1,689 words) - 01:31, 19 August 2024
  • Neurotrophic factor receptors or neurotrophin receptors are a group of growth factor receptors which specifically bind to neurotrophins (neurotrophic factors). Two...
    5 KB (670 words) - 10:25, 10 April 2025
  • Thumbnail for Interleukin 34
    known as monocytes; it elicits its activity by binding the Colony stimulating factor 1 receptor. Messenger RNA (mRNA) expression of human IL-34 is most abundant...
    2 KB (283 words) - 16:12, 28 October 2022
  • Thumbnail for Pexidartinib
    improvement with surgery. Pexidartinib blocks the activity of the colony-stimulating factor-1 receptor (CSF-1R). Common side effects are increased lactate dehydrogenase...
    10 KB (676 words) - 18:41, 14 June 2025
  • Growth factor receptor inhibitors (growth factor inhibitors, growth factor receptor blockers, growth factor blockers, growth factor receptor antagonists...
    4 KB (389 words) - 04:03, 24 May 2025
  • Receptor tyrosine kinase Granulocyte-colony stimulating factor (G-CSF) Granulocyte-macrophage colony stimulating factor (GM-CSF) Nerve growth factor (NGF)...
    25 KB (3,126 words) - 16:03, 10 June 2025
  • Thumbnail for Fibroblast growth factor receptor 1
    Fibroblast growth factor receptor 1 (FGFR-1), also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2 / Pfeiffer syndrome...
    44 KB (5,003 words) - 14:24, 24 February 2025
  • Thumbnail for Suppressor of cytokine signaling 1
    has been shown to interact with: Tax, CD117, Colony stimulating factor 1 receptor Growth hormone receptor, IRS2, Janus kinase 2, and TEC. SOCS JAK-STAT...
    16 KB (1,957 words) - 06:54, 14 July 2024
  • Thumbnail for Tyrosine kinase
    growth factor receptor (VEGFR), platelet-derived growth factor receptor (PDGFR), stem cell factor receptor, and colony-stimulating factor-1 receptor (Burstein...
    44 KB (5,283 words) - 12:50, 27 December 2024
  • Thumbnail for Microglia
    molecular process. Yolk sac progenitor cells require activation colony stimulating factor 1 receptor (CSF1R) for migration into the brain and differentiation...
    51 KB (5,999 words) - 03:03, 15 June 2025
  • Thumbnail for Nerve growth factor
    This pathway begins with the Trk receptor complex-recruitment of a second adaptor protein called growth factor-receptor bound protein-2 (Grb2) along with...
    27 KB (3,118 words) - 21:39, 29 May 2025
  • Thumbnail for VEGF receptor
    VEGF receptors (VEGFRs) are receptors for vascular endothelial growth factor (VEGF). There are three main subtypes of VEGFR, numbered 1, 2 and 3. Depending...
    8 KB (754 words) - 13:03, 18 September 2024