Active targeting of drug-loaded nanoparticles enhances the effects of passive targeting to make the nanoparticle more specific to a target site. There...

A biological target is anything within a living organism to which some other entity (like an endogenous ligand or a drug) is directed and/or binds, resulting...

of Drug Targeting is a peer-reviewed medical journal published by Informa that covers research on all aspects of drug delivery and drug targeting for...

biotechnology and pharmacology, drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered by identifying...

are registered. Vintafolide is a small molecule drug conjugate consisting of a small molecule targeting the folate receptor. It is currently in clinical...

a special reversal form of drug delivery called chemotactic drug targeting. By using chemical agents to help guide a drug carrier to a specific location...

its target site to achieve a desired therapeutic effect. Principles related to drug preparation, route of administration, site-specific targeting, metabolism...

drug is any chemical substance that when consumed causes a change in an organism's physiology, including its psychology, if applicable.[vague] Drugs are...

of finding new medications based on the knowledge of a biological target. The drug is most commonly an organic small molecule that activates or inhibits...

delivery system. Mechanisms for drug targeting in the brain involve going either "through" or "behind" the BBB. Modalities for drug delivery to the brain in...

progress (by 2009) targeting these sites. Chemoproteomics techniques have recently expanded the scope of what is deemed a druggable target through the identification...

coating is also an effective method to obtain drug targeting (such as gastro-resistant drugs). Other drugs such as some anthelmintics may need to reach a...

(anticancer) payload or drug. Antibody–drug conjugates are an example of bioconjugates and immunoconjugates. ADCs combine the targeting properties of monoclonal...

Target-mediated drug disposition (TMDD) is the process in which a drug binds with high affinity to its pharmacological target (for example, a receptor)...

than one drug, it is said to be multidrug-resistant. The development of antibiotic resistance in particular stems from the drugs targeting only specific...

The DrugBank database is a comprehensive, freely accessible, online database containing information on drugs and drug targets created and maintained by...

have been one such target in clinical trials. This B7-H3 protein is expressed on cancer cell for several types of cancer. Often, the drug will contain two...

binding to the same biological target), similar modes of action, and/or are used to treat the similar diseases. The Food and Drug Administration (FDA) has worked...

pharmacokinetic (drug absorption, distribution, metabolism, and elimination), pharmacodynamic (effects mediated through a drug's biological targets), and/or immunogenic...

psychoactive drug, or psychoactive substance, among other names such as psychoactive agent, psychopharmaceutical, and psychotropic drug, is a chemical...

topoisomerase inhibitors (i.e. etoposide, doxorubicin), microtubule-targeted drugs (i.e. vinblastine), and tyrosine kinase inhibitors (i.e. gefitinib,...

RNA-targeting small molecules represent a class of small molecules, organic compounds with traditional drug properties (e.g., Lipinski's rule of five)...

achieve drug targeting at a selected organ or site, SDs are designed to afford a differential distribution that can be regarded as reverse targeting. Since...

antiepileptic drugs, since GABA can itself, directly or indirectly, act proconvulsively. Another potential target of antiepileptic drugs is the peroxisome...

Antiviral drugs are a class of medication used for treating viral infections. Most antivirals target specific viruses, while a broad-spectrum antiviral...

transmucosal drug delivery. The retro-Michael reactions resulting in maleimide-thiol adducts require precise control. The targeting ability of drugs containing...

phenotypic drug discovery, a paradigm that aims to discover lead compounds on the basis of alleviating a disease phenotype, as opposed to target-based drug discovery...

healthy cells, as in targeted therapy or targeted drug delivery This disambiguation page lists articles associated with the title Smart drug. If an internal...

agents, understanding hepatocarcinogenesis [citation needed], and for drug targeting studies [citation needed]. Hep G2 cells are also employed in trials...

2015). "Activation of RAS family members confers resistance to ROS1 targeting drugs". Oncotarget. 6 (7): 5182–94. doi:10.18632/oncotarget.3311. PMC 4467141...