Genome-wide complex trait analysis (GCTA) Genome-based restricted maximum likelihood (GREML) is a statistical method for heritability estimation in genetics...
32 KB (3,510 words) - 17:14, 5 June 2024
In genomics, a genome-wide association study (GWA study, or GWAS), is an observational study of a genome-wide set of genetic variants in different individuals...
72 KB (7,011 words) - 00:57, 24 June 2025
using mixed effects models implemented in software such as genome-wide complex trait analysis (GCTA). To do this, researchers find the average genetic relatedness...
83 KB (8,028 words) - 01:10, 3 July 2025
for genome-wide interaction analysis (GWIA) of case-control SNP data and analysis of quantitative traits Precision Mapping of Quantitative Trait Loci...
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Heritability (redirect from Heritable trait)
Goddard ME, Visscher PM (January 2011). "GCTA: a tool for genome-wide complex trait analysis". American Journal of Human Genetics. 88 (1): 76–82. doi:10...
47 KB (5,644 words) - 00:19, 21 July 2025
Polygenic score (redirect from Genome-wide score)
individual's phenotype. The PGS is also called the polygenic index (PGI) or genome-wide score; in the context of disease risk, it is called a polygenic risk...
60 KB (6,735 words) - 17:57, 17 July 2025
Bacterial genome size Cryoconservation of animal genetic resources DNA methylation Genome Browser Genome Compiler Genome topology Genome-wide association...
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Genetics (redirect from Genetic trait)
to look for locations in the genome that are associated with diseases, a method especially useful for multigenic traits not clearly defined by a single...
99 KB (10,492 words) - 21:21, 31 July 2025
examining both human and pig quantitative trait loci through a method known as genome-wide complex trait analysis (GCTA), which allowed the researchers to...
23 KB (2,688 words) - 05:18, 19 July 2025
Gene-environment interaction Gene-environment correlation Genome-wide complex trait analysis Heritability Heritability of IQ Human nature Identical Strangers:...
67 KB (7,951 words) - 19:23, 23 June 2025
studied with statistical techniques like quantitative trait loci (QTL) mapping, and genome-wide association studies (GWAS) on a large scale. The overall...
27 KB (2,719 words) - 06:51, 25 June 2025
(August 2016). "Genome-wide association study using whole-genome sequencing rapidly identifies new genes influencing agronomic traits in rice". Nature...
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prioritization of candidate causal genes in candidate gene analysis following genome-wide association studies. TWAS looks at the RNA products of a specific...
22 KB (2,971 words) - 16:55, 24 June 2025
An epigenome-wide association study (EWAS) is an examination of a genome-wide set of quantifiable epigenetic marks, such as DNA methylation, in different...
32 KB (3,597 words) - 00:07, 10 July 2025
was supported by the introduction of Genome-wide complex trait analysis (GCTA) in 2010, which demonstrated that trait similarity could be predicted by the...
14 KB (1,730 words) - 01:44, 11 July 2025
Personal genomics (redirect from Genome analysis)
the branch of genomics concerned with the sequencing, analysis and interpretation of the genome of an individual. The genotyping stage employs different...
40 KB (4,463 words) - 04:36, 15 July 2025
Protein quantitative trait loci (pQTL) are regions in the genome associated with variation in protein expression levels. Since proteins are the primary...
47 KB (4,858 words) - 12:09, 29 July 2025
E. coli long-term evolution experiment (section Genomic analysis of the Cit+ trait and implications for evolutionary innovation)
the results of a genomic analysis of the Cit+ trait that shed light on the genetic basis and evolutionary history of the trait. The researchers had sequenced...
54 KB (6,632 words) - 20:36, 26 July 2025
R.; Jaffe, Andrew E. (2021-09-02). "Genome-wide sequencing-based identification of methylation quantitative trait loci and their role in schizophrenia...
58 KB (6,253 words) - 22:18, 15 July 2025
personality traits, also known as the five-factor model (FFM) or the OCEAN model, is the prevailing model for personality traits. When factor analysis (a statistical...
24 KB (2,999 words) - 05:15, 2 March 2025
In bioinformatics, sequence analysis is the process of subjecting a DNA, RNA or peptide sequence to any of a wide range of analytical methods to understand...
33 KB (3,862 words) - 18:08, 23 July 2025
Goddard, M. E.; Visscher, P. M. (2011). "GCTA: A tool for genome-wide complex trait analysis". The American Journal of Human Genetics. 88 (1): 76–82. doi:10...
11 KB (783 words) - 06:00, 20 March 2023
based on summary statistics from genome-wide association studies (GWASs). The approach involves using regression analysis to examine the relationship between...
7 KB (799 words) - 07:04, 3 December 2023
Neanderthal genetics (redirect from Neanderthal genome)
became possible in the 1990s with advances in ancient DNA analysis. In 2008, the Neanderthal genome project published the full sequence Neanderthal mitochondrial...
66 KB (6,693 words) - 20:24, 8 July 2025
Bioinformatics (section Genome annotation)
provides. Genome-wide association studies have successfully identified thousands of common genetic variants for complex diseases and traits; however,...
133 KB (8,523 words) - 14:27, 29 July 2025
CRISPR gene editing (category Genome editing)
system. By delivering the Cas9 nuclease complexed with a synthetic guide RNA (gRNA) into a cell, the cell's genome can be cut at a desired location, allowing...
181 KB (20,908 words) - 13:53, 25 July 2025
Genetic linkage (redirect from Linkage analysis)
Daly; Hirschhorn, Joel N. (2005-02-01). "Genome-wide association studies for common diseases and complex traits". Nature Reviews Genetics. 6 (2): 95–108...
31 KB (4,032 words) - 19:24, 23 July 2025
Andre Franke (section Genome wide association study)
Thomas C.G. Bosch. His dissertation was titled "A systematic genome-wide association analysis for Inflammatory Bowel Diseases." Following his doctor rerum...
20 KB (1,630 words) - 15:52, 17 July 2025
Genome editing, or genome engineering, or gene editing, is a type of genetic engineering in which DNA is inserted, deleted, modified or replaced in the...
79 KB (9,365 words) - 22:34, 17 July 2025