• Genome-wide complex trait analysis (GCTA) Genome-based restricted maximum likelihood (GREML) is a statistical method for heritability estimation in genetics...
    32 KB (3,510 words) - 17:14, 5 June 2024
  • Thumbnail for Genome-wide association study
    In genomics, a genome-wide association study (GWA study, or GWAS), is an observational study of a genome-wide set of genetic variants in different individuals...
    72 KB (7,011 words) - 00:57, 24 June 2025
  • using mixed effects models implemented in software such as genome-wide complex trait analysis (GCTA). To do this, researchers find the average genetic relatedness...
    83 KB (8,028 words) - 01:10, 3 July 2025
  • for genome-wide interaction analysis (GWIA) of case-control SNP data and analysis of quantitative traits Precision Mapping of Quantitative Trait Loci...
    30 KB (3,609 words) - 16:53, 26 March 2025
  • Thumbnail for Heritability
    Heritability (redirect from Heritable trait)
    Goddard ME, Visscher PM (January 2011). "GCTA: a tool for genome-wide complex trait analysis". American Journal of Human Genetics. 88 (1): 76–82. doi:10...
    47 KB (5,644 words) - 00:19, 21 July 2025
  • Thumbnail for Polygenic score
    individual's phenotype. The PGS is also called the polygenic index (PGI) or genome-wide score; in the context of disease risk, it is called a polygenic risk...
    60 KB (6,735 words) - 17:57, 17 July 2025
  • Thumbnail for Genome
    Bacterial genome size Cryoconservation of animal genetic resources DNA methylation Genome Browser Genome Compiler Genome topology Genome-wide association...
    44 KB (4,932 words) - 18:09, 22 July 2025
  • Thumbnail for Genetics
    Genetics (redirect from Genetic trait)
    to look for locations in the genome that are associated with diseases, a method especially useful for multigenic traits not clearly defined by a single...
    99 KB (10,492 words) - 21:21, 31 July 2025
  • examining both human and pig quantitative trait loci through a method known as genome-wide complex trait analysis (GCTA), which allowed the researchers to...
    23 KB (2,688 words) - 05:18, 19 July 2025
  • Thumbnail for Twin study
    Gene-environment interaction Gene-environment correlation Genome-wide complex trait analysis Heritability Heritability of IQ Human nature Identical Strangers:...
    67 KB (7,951 words) - 19:23, 23 June 2025
  • Thumbnail for Complex traits
    studied with statistical techniques like quantitative trait loci (QTL) mapping, and genome-wide association studies (GWAS) on a large scale. The overall...
    27 KB (2,719 words) - 06:51, 25 June 2025
  • Thumbnail for Whole genome sequencing
    (August 2016). "Genome-wide association study using whole-genome sequencing rapidly identifies new genes influencing agronomic traits in rice". Nature...
    115 KB (9,592 words) - 17:15, 22 July 2025
  • prioritization of candidate causal genes in candidate gene analysis following genome-wide association studies. TWAS looks at the RNA products of a specific...
    22 KB (2,971 words) - 16:55, 24 June 2025
  • Thumbnail for Epigenome-wide association study
    An epigenome-wide association study (EWAS) is an examination of a genome-wide set of quantifiable epigenetic marks, such as DNA methylation, in different...
    32 KB (3,597 words) - 00:07, 10 July 2025
  • was supported by the introduction of Genome-wide complex trait analysis (GCTA) in 2010, which demonstrated that trait similarity could be predicted by the...
    14 KB (1,730 words) - 01:44, 11 July 2025
  • the branch of genomics concerned with the sequencing, analysis and interpretation of the genome of an individual. The genotyping stage employs different...
    40 KB (4,463 words) - 04:36, 15 July 2025
  • Thumbnail for Protein quantitative trait loci
    Protein quantitative trait loci (pQTL) are regions in the genome associated with variation in protein expression levels. Since proteins are the primary...
    47 KB (4,858 words) - 12:09, 29 July 2025
  • Thumbnail for E. coli long-term evolution experiment
    the results of a genomic analysis of the Cit+ trait that shed light on the genetic basis and evolutionary history of the trait. The researchers had sequenced...
    54 KB (6,632 words) - 20:36, 26 July 2025
  • Thumbnail for Single-nucleotide polymorphism
    R.; Jaffe, Andrew E. (2021-09-02). "Genome-wide sequencing-based identification of methylation quantitative trait loci and their role in schizophrenia...
    58 KB (6,253 words) - 22:18, 15 July 2025
  • personality traits, also known as the five-factor model (FFM) or the OCEAN model, is the prevailing model for personality traits. When factor analysis (a statistical...
    24 KB (2,999 words) - 05:15, 2 March 2025
  • In bioinformatics, sequence analysis is the process of subjecting a DNA, RNA or peptide sequence to any of a wide range of analytical methods to understand...
    33 KB (3,862 words) - 18:08, 23 July 2025
  • Thumbnail for Michael Goddard
    Goddard, M. E.; Visscher, P. M. (2011). "GCTA: A tool for genome-wide complex trait analysis". The American Journal of Human Genetics. 88 (1): 76–82. doi:10...
    11 KB (783 words) - 06:00, 20 March 2023
  • based on summary statistics from genome-wide association studies (GWASs). The approach involves using regression analysis to examine the relationship between...
    7 KB (799 words) - 07:04, 3 December 2023
  • became possible in the 1990s with advances in ancient DNA analysis. In 2008, the Neanderthal genome project published the full sequence Neanderthal mitochondrial...
    66 KB (6,693 words) - 20:24, 8 July 2025
  • Thumbnail for Bioinformatics
    provides. Genome-wide association studies have successfully identified thousands of common genetic variants for complex diseases and traits; however,...
    133 KB (8,523 words) - 14:27, 29 July 2025
  • Thumbnail for CRISPR gene editing
    CRISPR gene editing (category Genome editing)
    system. By delivering the Cas9 nuclease complexed with a synthetic guide RNA (gRNA) into a cell, the cell's genome can be cut at a desired location, allowing...
    181 KB (20,908 words) - 13:53, 25 July 2025
  • Daly; Hirschhorn, Joel N. (2005-02-01). "Genome-wide association studies for common diseases and complex traits". Nature Reviews Genetics. 6 (2): 95–108...
    31 KB (4,032 words) - 19:24, 23 July 2025
  • Thumbnail for Andre Franke
    Thomas C.G. Bosch. His dissertation was titled "A systematic genome-wide association analysis for Inflammatory Bowel Diseases." Following his doctor rerum...
    20 KB (1,630 words) - 15:52, 17 July 2025
  • Thumbnail for Oat
    Oat (section Genome)
    in) from other "A" genome species have contributed many valuable traits, like resistance to oat crown rust. Pc98 is one such trait, introgressed from...
    48 KB (5,143 words) - 08:53, 3 August 2025
  • Thumbnail for Genome editing
    Genome editing, or genome engineering, or gene editing, is a type of genetic engineering in which DNA is inserted, deleted, modified or replaced in the...
    79 KB (9,365 words) - 22:34, 17 July 2025