• Thumbnail for Glycogen synthase
    Glycogen synthase (UDP-glucose-glycogen glucosyltransferase) is a key enzyme in glycogenesis, the conversion of glucose into glycogen. It is a glycosyltransferase...
    16 KB (1,749 words) - 13:27, 24 October 2024
  • Thumbnail for GSK-3
    Glycogen synthase kinase 3 (GSK-3) is a serine/threonine protein kinase that mediates the addition of phosphate molecules onto serine and threonine amino...
    50 KB (5,792 words) - 16:31, 8 March 2025
  • Thumbnail for Glycogen synthase kinase-3 beta
    Glycogen synthase kinase-3 beta, (GSK-3 beta), is an enzyme that in humans is encoded by the GSK3B gene. In mice, the enzyme is encoded by the Gsk3b gene...
    17 KB (1,819 words) - 16:52, 22 May 2024
  • Thumbnail for Glycogen storage disease type 0
    Glycogen storage disease type 0 is a disease characterized by a deficiency in the glycogen synthase enzyme (GSY). Although glycogen synthase deficiency...
    12 KB (1,412 words) - 04:27, 30 January 2025
  • Thumbnail for Glycogen branching enzyme
    terminal residue of glycogen to form an α-1,4-glycosidic linkage, a reaction catalyzed by glycogen synthase. Importantly, glycogen synthase can only catalyze...
    25 KB (2,827 words) - 19:18, 29 August 2024
  • Once a chain of seven glucose monomers is formed, glycogen synthase binds to the growing glycogen chain and adds UDP-glucose to the 4-hydroxyl group...
    5 KB (616 words) - 14:19, 14 November 2024
  • Thumbnail for Glycogen
    the action of several enzymes, including glycogen synthase. Glucose molecules are added to the chains of glycogen as long as both insulin and glucose remain...
    35 KB (4,112 words) - 05:10, 19 September 2024
  • Thumbnail for Glucose 6-phosphate
    the activated UDP-glucose can add to a growing glycogen molecule with the help of glycogen synthase. This is a very efficient storage mechanism for glucose...
    10 KB (966 words) - 19:14, 2 January 2025
  • known as glycogen synthase. This bond may be broken by amylase when the body wishes to break down glycogen into glucose for energy. Glycogen branching...
    18 KB (2,416 words) - 01:53, 17 April 2025
  • Thumbnail for Phosphorylation
    as an effector, stimulates glycogen synthase, and glucose-6-phosphate may inhibit the phosphorylation of glycogen synthase by cyclic AMP-stimulated protein...
    17 KB (1,824 words) - 07:11, 15 May 2025
  • Thumbnail for Joan Guinovart
    January 2025) was a Spanish biochemist known for research on glycogen and liver glycogen synthase, as well as for work in FEBS, IUBMB and the Spanish Society...
    15 KB (1,450 words) - 19:53, 3 May 2025
  • Thumbnail for Glycogenin
    This hints at the role of glycogenin to simply start glycogen synthesis before glycogen synthase takes over. Glycogenin was discovered in 1984 by Dr....
    10 KB (1,043 words) - 06:25, 23 September 2024
  • Thumbnail for Glycogen storage disease
    / GSD9C / GSD9D. GSD type 0: Although glycogen synthase deficiency does not result in storage of extra glycogen in the liver, it is classified with the...
    69 KB (6,188 words) - 20:52, 10 January 2025
  • Thumbnail for Glycogenin-1
    biosynthesis of glycogen. It is capable of self-glucosylation, forming an oligosaccharide primer that serves as a substrate for glycogen synthase. This is done...
    9 KB (1,200 words) - 03:32, 12 January 2025
  • Thumbnail for Glycogen phosphorylase
    Glycogen phosphorylase is one of the phosphorylase enzymes (EC 2.4.1.1). Glycogen phosphorylase catalyzes the rate-limiting step in glycogenolysis in...
    26 KB (2,918 words) - 16:51, 15 September 2024
  • Thumbnail for Insulin
    formation of glycogen. Also, insulin activates the enzymes phosphofructokinase and glycogen synthase which are responsible for glycogen synthesis. Decreased...
    121 KB (13,818 words) - 04:18, 12 May 2025
  • known as glycogen synthase. This bond may be broken by amylase when the body wishes to break down glycogen into glucose for energy. Glycogen branching...
    6 KB (729 words) - 19:33, 8 June 2024
  • Buschiazzo, Alejandro (2004). "Crystal structure of glycogen synthase: homologous enzymes catalyze glycogen synthesis and degradation". The EMBO Journal. 23...
    10 KB (1,107 words) - 05:27, 3 June 2024
  • Thumbnail for Anabolism
    by UTP--glucose-1-phosphate uridylyltransferase. Glycogen synthase adds this UDP-glucose to a glycogen chain. Glucagon is traditionally a catabolic hormone...
    11 KB (1,051 words) - 16:20, 28 November 2024
  • Thumbnail for Tideglusib
    Tideglusib (NP-12, NP031112) is a potent and irreversible small molecule glycogen synthase kinase 3 (GSK-3) inhibitor. Tideglusib has been evaluated in clinical...
    6 KB (509 words) - 20:52, 24 March 2025
  • Thumbnail for Insulin receptor
    PKB also phosphorylates and inhibits glycogen synthase kinase, which is an enzyme that inhibits glycogen synthase. Therefore, PKB acts to start the process...
    32 KB (3,920 words) - 18:44, 1 May 2025
  • Thumbnail for Lithium (medication)
    molecular targets: Lithium both directly and indirectly inhibits GSK3β (glycogen synthase kinase 3β) which results in the activation of mTOR. This leads to...
    105 KB (11,203 words) - 01:37, 14 May 2025
  • Thumbnail for Metabolism
    and glycogen. The metabolism of glycogen is controlled by activity of phosphorylase, the enzyme that breaks down glycogen, and glycogen synthase, the...
    116 KB (12,647 words) - 00:56, 9 May 2025
  • glycosyltransferase that enable the transfer of glucose. Examples include: glycogen synthase glycogen phosphorylase They are categorized under EC number 2.4.1. edited...
    738 bytes (76 words) - 18:24, 23 January 2024
  • Thumbnail for Uridine diphosphate
    pyrophosphate ion in the process. Then, the enzyme glycogen synthase combines UDP-glucose units to form a glycogen chain. The UDP molecule is cleaved from the...
    3 KB (138 words) - 21:44, 27 March 2025
  • [glycogen-synthase-D] phosphatase ({EC 3.1.3.42) catalyzes the reaction [glycogen-synthase D] + H2O ⇌ {\displaystyle \rightleftharpoons } [glycogen-synthase...
    2 KB (132 words) - 12:18, 26 August 2023
  • Thumbnail for GSK3A
    Glycogen synthase kinase-3 alpha is an enzyme that in humans is encoded by the GSK3A gene. Glycogen synthase kinase 3-alpha EC 2.7.1.37 is a multifunctional...
    2 KB (212 words) - 06:36, 18 December 2023
  • corporation Galatasaray S.K., a Turkish sports club based in Istanbul Glycogen synthase kinase Golden State Killer, a California serial rapist and murderer...
    360 bytes (72 words) - 09:27, 17 May 2025
  • Thumbnail for Protein phosphatase 1
    phosphorylated glycogen synthase (p-GS) independently and recruit p-GS towards PP1, allowing PP1 to dephosphorylate and thereby activate glycogen synthase independent...
    18 KB (2,050 words) - 09:57, 6 February 2025
  • Thumbnail for Protein kinase A
    11.11). PKA has several functions in the cell, including regulation of glycogen, sugar, and lipid metabolism. It should not be confused with 5'-AMP-activated...
    27 KB (2,665 words) - 16:53, 12 May 2025