MHC class I polypeptide–related sequence A (MICA) is a highly polymorphic cell surface glycoprotein encoded by the MICA gene located within MHC locus...
10 KB (1,266 words) - 23:26, 3 March 2023
MHC class I polypeptide-related sequence B (MICB) is a protein that is encoded by the MICB gene located within MHC locus. MICB is related to MHC class...
9 KB (1,097 words) - 12:23, 5 April 2024
MHC Class II molecules are a class of major histocompatibility complex (MHC) molecules normally found only on professional antigen-presenting cells such...
17 KB (2,119 words) - 03:03, 6 March 2025
MICA (missile), a French anti-aircraft missile system MHC class I polypeptide-related sequence A, a cell surface protein Mica, Cluj, a commune in Cluj...
3 KB (369 words) - 16:45, 22 April 2025
display MHC class I molecules, or display stress markers such as MHC class I polypeptide–related sequence A (MIC-A). Decreased expression of MHC class I and...
32 KB (3,212 words) - 08:43, 13 June 2025
MHC class I molecules are one of two primary classes of major histocompatibility complex (MHC) molecules (the other being MHC class II) and are found...
23 KB (2,917 words) - 21:51, 25 May 2025
needed] The MHC gene family is divided into three subgroups: MHC class I, MHC class II, and MHC class III. Among all those genes present in MHC, there are...
58 KB (6,838 words) - 17:51, 11 July 2025
NKG2D binds MHC class I homologues MIC-A (MHC class I polypeptide-related sequence A), MIC-B and ULBP (UL-16 binding protein) in human. MIC-A and MIC-B...
11 KB (1,565 words) - 10:27, 2 March 2023
is not known. These proteins are called MHC class I polypeptide-related sequence A and B. Discovered by sequence homology analysis these proteins are found...
47 KB (5,077 words) - 12:20, 31 March 2025
HLA-A, HLA-B, HLA-C: major histocompatibility complex (MHC), class I, A, B, and C loci. (6p21.3) HLA-DQA1 and HLA-DQB1 form HLA-DQ heterodimer MHC class II...
35 KB (2,411 words) - 03:59, 15 July 2025
Jan Klein (category Articles with a promotional tone from January 2020)
polypeptide (T,G)-L—A into the Mhc. Klein and his coworkers, finding their locus inseparable from the postulated Ir-1 locus, concluded that the class...
36 KB (4,880 words) - 02:22, 22 May 2024
proliferation. This gene localizes to the major histocompatibility complex (MHC class III) region on chromosome 6. This cluster includes several genes involved...
9 KB (1,095 words) - 23:51, 15 June 2025
T-cell receptor (category Protein pages needing a picture)
produce a variety of polypeptides with both constant and variable regions. When the TCR engages with antigenic peptide and MHC (peptide/MHC), the T lymphocyte...
44 KB (5,378 words) - 07:54, 5 May 2025
Interferon (redirect from Interferon type i)
complex molecules, MHC I and MHC II, and increase immunoproteasome activity. All interferons significantly enhance the presentation of MHC I dependent antigens...
63 KB (7,124 words) - 04:51, 12 July 2025
histocompatibility complex III (MHC class III) close to the Complement component 4 genes C4A and C4B, the Tenascin X gene TNXB and STK19. MHC class III is the most gene-dense...
50 KB (5,618 words) - 11:35, 1 July 2025
encodes the alpha subunit of HLA-DR. Unlike the alpha chains of other Human MHC class II molecules, the alpha subunit is practically invariable. However it...
9 KB (1,145 words) - 03:20, 25 December 2023
Skeletal muscle (redirect from Type I muscle fiber)
referred to as "MHC fiber type", e.g. "MHC IIa fibers", and results from determination of different MHC isoforms. These methods are closely related physiologically...
119 KB (13,832 words) - 14:57, 27 June 2025
Myosin light chain (section Myosin light chain classes)
A myosin light chain is a light chain (small polypeptide subunit) of myosin. Myosin light chains were discovered by Chinese biochemist Cao Tianqin (Tien-chin...
8 KB (1,021 words) - 04:00, 28 May 2025
located in lipid rafts and major histocompatibility (MHC) class I molecule. Binding of SV40 with MHC class I molecules triggers receptor clustering and redistribution...
57 KB (6,662 words) - 11:27, 28 April 2025
MHC class II regulatory factor RFX1 is a protein that, in humans, is encoded by the RFX1 gene located on the short arm of chromosome 19. The RFX1 gene...
11 KB (1,448 words) - 01:28, 3 December 2023
neurotrophic factor is a protein that in humans is encoded by the CNTF gene. The protein encoded by this gene is a polypeptide hormone and neurotrophic...
15 KB (1,748 words) - 16:47, 2 October 2024
"Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region"...
6 KB (804 words) - 09:51, 17 October 2022
Telomerase (category Aging-related enzymes)
a ribonucleoprotein that adds a species-dependent telomere repeat sequence to the 3' end of telomeres. A telomere is a region of repetitive sequences...
50 KB (5,791 words) - 17:17, 23 May 2025
numerous MHC class-I restricted T cell epitopes. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core...
32 KB (3,960 words) - 12:16, 9 June 2025
processes are followed. Antigens are broken down by proteasomes. Class I and class II MHC molecules then attach to the antigen and transport it to the cellular...
78 KB (8,020 words) - 21:34, 29 May 2025
peptides), to immunological defense (as MHC class I and II, cytokinins), and as regulatory peptides displaying more than a single action. These peptides result...
22 KB (2,824 words) - 12:22, 5 July 2025
four separate polypeptides, which occur mostly in bacteria, or present in one or two multi-domain polypeptides. When the polypeptides are one domain...
111 KB (14,448 words) - 00:51, 28 May 2025
hydrogen bonding and by close contacts with a region called the "B pocket" on the MHC surface. Many MHC class I alleles prefer hydrophobic C-terminal residues...
140 KB (16,810 words) - 07:35, 7 July 2025
AP-1 transcription factor (category Protein pages needing a picture)
leucines appearing at every seventh position of the polypeptide chain. Due to the amino acid sequence and the periodicity of the helices, the leucine side...
42 KB (4,614 words) - 10:42, 5 February 2025