In epidemiology, Mendelian randomization (commonly abbreviated to MR) is a method using measured variation in genes to examine the causal effect of an...
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Mendelian inheritance (also known as Mendelism) is a type of biological inheritance following the principles originally proposed by Gregor Mendel in 1865...
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Causal model (section Mendelian randomization)
form a single instrument[clarification needed].: 257 Definition: Mendelian randomization uses measured variation in genes of known function to examine the...
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of phenotypic correlations, social inequality, attempts to use Mendelian randomization in causal inference, the understanding of the biological origins...
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Genetics (section Mendelian genetics)
disease. At the population level, researchers take advantage of Mendelian randomization to look for locations in the genome that are associated with diseases...
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Jiahao; Lei, Xiangyu; Luo, Guogang (2024-07-22). "Multi-omics Mendelian randomization integrating GWAS, eQTL and pQTL data revealed GSTM4 as a potential...
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Non-Mendelian inheritance is any pattern in which traits do not segregate in accordance with Mendel's laws. These laws describe the inheritance of traits...
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acid are associated with hypertension and evidence from genetic (Mendelian Randomization) studies and clinical trials indicate this relationship is likely...
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elevated levels of inflammatory markers and clotting factors. Mendelian randomization indicates a causal relationship of inflammation leading to atrial...
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Magnetoresistance, change in electrical resistance due to a magnetic field Mendelian randomization, a way of using genetic information to estimate causal effects...
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include discordant twin studies, children of twins designs, and Mendelian randomization. There are many broad conclusions to be drawn from behavioural...
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for instrumental variable analysis with genetic instruments ('Mendelian randomization'): Example with urate transporter SLC2A9 as an instrumental variable...
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outcomes: an umbrella review and meta-analysis of observational and Mendelian randomization studies". European Heart Journal. 42 (34): 3388–3403. doi:10...
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"The Correlation between Relatives on the Supposition of Mendelian Inheritance" is a scientific paper by Ronald Fisher which was published in the Transactions...
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Epidemiology (section Random error)
transmissionPages displaying short descriptions of redirect targets Mendelian randomization – Statistical method in genetic epidemiology Occupational epidemiology –...
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either family or population studies. Epigenetics Genetic disorder Mendelian randomization Molecular epidemiology Mutation Population genetics Hardy–Weinberg...
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and metabolic disorders. Another study utilized a two-sample Mendelian randomization (TSMR) approach to explore causal relationships between IgAN and...
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linear unbiased prediction Mendelian randomization Pleiotropy "The Correlation between Relatives on the Supposition of Mendelian Inheritance", Fisher 1918...
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Diabetes, Lifestyle Factors, and Risk of Gallstone Disease: A Mendelian Randomization Investigation". Clinical Gastroenterology and Hepatology. 20 (3):...
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Analysis of variance (redirect from Analysis of variance/Random effects models)
and randomization is similar to the design-based inference that is standard in finite-population survey sampling. Kempthorne uses the randomization-distribution...
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between daytime napping, cognitive function, and brain volume? A Mendelian randomization study in the UK Biobank". Sleep Health. 9 (5): 786–793. doi:10...
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PMC 3170645. PMID 21851605. Burgess S, Davey Smith G (August 2017). "Mendelian Randomization Implicates High-Density Lipoprotein Cholesterol–Associated Mechanisms...
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from a systematic review and meta-analysis of randomized controlled trials and a Mendelian randomization study". Archives of Medical Science. 18 (2): 466–479...
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study of allelic effects. Mendelian randomization of alleles also provides opportunities to study the effects of alleles at random with respect to their associated...
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PMID 30961569. Ho J, Mak CC, Sharma V, To K, Khan W (October 2022). "Mendelian Randomization Studies of Lifestyle-Related Risk Factors for Osteoarthritis: A...
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large part due to various selection biases and competing risks. Mendelian randomization studies have been inconsistent regarding the risk curve, with three...
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Microbiota-Dependent Metabolites and Cardiometabolic Health: A Bidirectional Mendelian Randomization Analysis". Diabetes. 68 (9): 1747–1755. doi:10.2337/db19-0153....
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also influenced by the person's socioeconomic status. In a study, Mendelian randomization was used to identify causal relationships between chronic pain...
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Microbiota–Dependent Metabolites and Cardiometabolic Health: A Bidirectional Mendelian Randomization Analysis". Diabetes. 68 (9): 1747–1755. doi:10.2337/db19-0153....
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Sakaue S, Akiyama M, Kiiskinen TT, Zhou W, et al. (January 2022). "Mendelian randomization of genetically independent aging phenotypes identifies LPA and...
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