• Thumbnail for PC12 cell line
    PC12 is a cell line derived from a pheochromocytoma of the rat adrenal medulla, that have an embryonic origin from the neural crest that has a mixture...
    10 KB (1,002 words) - 02:01, 3 December 2023
  • PC12 may refer to: PC12 cell line, in biotechnology PC12 minicomputer Pilatus PC-12, a civilian aircraft BAP Río Chira (PC 12), a vessel of the Peruvian...
    429 bytes (66 words) - 12:26, 14 March 2025
  • Thumbnail for Cell culture
    calvarium) Rat tumor cell lines GH3 (pituitary tumor) PC12 (pheochromocytoma) Other mammal cell lines BHK21 cell (Baby Hamster Kidney) MDBK cell (Madin-Darby...
    109 KB (8,502 words) - 21:10, 22 May 2025
  • SH-SY5Y (category Human cell lines)
    SH-SY5Y is a human derived cell line used in scientific research. The original cell line, called SK-N-SH, from which it was subcloned was isolated from...
    13 KB (1,485 words) - 02:08, 27 December 2024
  • and Borrego JJ. 1998. Neurotoxic effect on two fish species and a PC12 cell line of the supernate of Vibrio alginolyticus and Vibrio anguillarum. Veterinary...
    19 KB (2,605 words) - 07:07, 20 May 2025
  • Thumbnail for Anaplastic lymphoma kinase
    demonstrated that ALK activation promotes neuronal differentiation of PC12 or neuroblastoma cell lines. ALK is critical for embryonic development in Drosophila...
    48 KB (5,304 words) - 19:53, 30 April 2025
  • Thumbnail for Protein BTG2
    progenitor cells. Moreover, when directly overexpressed in vivo in neural progenitor cells, BTG2 induces their differentiation. In fact, in the neuronal PC12 cell...
    26 KB (3,182 words) - 08:36, 6 May 2024
  • Thumbnail for GRB2
    GRB2 (category Cell signaling)
    phosphatase to FRS2 is essential for fibroblast growth factor-induced PC12 cell differentiation". Molecular and Cellular Biology. 18 (7): 3966–73. doi:10...
    82 KB (9,365 words) - 09:44, 2 March 2025
  • Thumbnail for SEPT2
    disruption of its GTPase activity promotes aberrant neurite sprouting in PC12 cells". NeuroReport. 14 (1): 31–7. doi:10.1097/00001756-200301200-00006. PMID 12544826...
    10 KB (1,266 words) - 06:29, 11 January 2024
  • Thumbnail for MRAS
    brain-specific Ras-related protein, activates Akt and promotes cell survival in PC12 cells". Oncogene. 19 (16): 2014–22. doi:10.1038/sj.onc.1203530. PMID 10803462...
    21 KB (2,597 words) - 05:11, 26 February 2024
  • Thumbnail for K252a
    been shown to block the neuronal differentiation of rat pheochromocytoma PC12 cells by inhibition of trk tyrosine kinase activity. K252a has been reported...
    4 KB (275 words) - 20:07, 24 September 2024
  • adhesion of neuron-like pc12 cells. Early cell adhesion is very important for preventing cell degeneration; the longer cells are suspended in culture...
    19 KB (2,235 words) - 04:05, 26 March 2025
  • Thumbnail for 3,4-Dihydroxyphenylacetaldehyde
    dopamine formed by monoamine oxidase (MAO). In differentiated neuronal cells of the PC12 line, physiological concentrations of DOPAL in isolated mitochondria...
    8 KB (608 words) - 21:53, 8 September 2024
  • Thumbnail for Exocytosis
    in permeabilized cells:  This is based on the studies on permeabilized neurosecretory cells, such as chromaffin and PC12.  These cells vesicle merging...
    19 KB (2,200 words) - 14:28, 19 April 2025
  • Thumbnail for Cocaine and amphetamine regulated transcript
    peptide stimulation of G protein-mediated signaling in differentiated PC12 cells: identification of PACAP 6-38 as a CART receptor antagonist". Neuropeptides...
    20 KB (2,393 words) - 00:20, 20 October 2024
  • Thumbnail for Stress granule
    Stress granule (category Cell biology)
    (September 2006). "Oxidative stress reveals heterogeneity of FMRP granules in PC12 cell neurites". Brain Research. 1112 (1): 56–64. doi:10.1016/j.brainres.2006...
    184 KB (12,563 words) - 05:08, 10 March 2025
  • differences in stimulus timing duration and dynamics. For example, treating PC12 cells with epidermal growth factor (EGF, inducing a transient profile of ERK...
    108 KB (11,930 words) - 18:27, 23 May 2025
  • Thumbnail for PIK3CB
    virus type-1 Tat protein activates phosphatidylinositol 3-kinase in PC12 neuronal cells". J. Biol. Chem. 271 (38): 22961–4. doi:10.1074/jbc.271.38.22961...
    8 KB (982 words) - 22:16, 27 March 2024
  • Thumbnail for Tyrosylprotein sulfotransferase
    Huttner WB (September 1983). "Tyrosine-O-sulfated proteins of PC12 pheochromocytoma cells and their sulfation by a tyrosylprotein sulfotransferase". J...
    11 KB (1,197 words) - 16:11, 26 August 2023
  • Thumbnail for Tropomyosin receptor kinase A
    Huntingtin disrupts growth factor receptor signaling in rat pheochromocytoma (PC12) cells". The Journal of Biological Chemistry. 277 (8): 6703–7. doi:10.1074/jbc...
    28 KB (3,328 words) - 15:54, 29 October 2024
  • Murphy, C. J. (June 2005). "Cooperative modulation of neuritogenesis by PC12 cells by topography and nerve growth factor". Biomaterials. 26 (17): 3639–3644...
    106 KB (14,549 words) - 22:54, 1 July 2024
  • Thumbnail for Myricetin
    Researchers have shown that PC12 cells treated with hydrogen peroxide (H2O2) as an oxidative stressor experience cell death due to apoptosis. When treated...
    27 KB (3,000 words) - 11:53, 11 February 2025
  • Thumbnail for Neurotransmitter
    peptide stimulation of G protein-mediated signaling in differentiated PC12 cells: identification of PACAP 6-38 as a CART receptor antagonist". Neuropeptides...
    100 KB (8,956 words) - 14:28, 23 May 2025
  • Thumbnail for SYT1
    PA, Südhof TC, Jahn R (Aug 1996). "Fatty acylation of synaptotagmin in PC12 cells and synaptosomes". Biochemical and Biophysical Research Communications...
    13 KB (1,503 words) - 18:51, 4 January 2024
  • Thumbnail for Tris(1,3-dichloro-2-propyl)phosphate
    several neurodevelopmental processes in a neuronal cell line. PC12 cells showed decreased cell replication and growth, increased oxidative stress, and...
    25 KB (2,739 words) - 01:04, 19 February 2025
  • 210.190.750 – pc12 cells MeSH A11.251.210.190.880 – u937 cells MeSH A11.251.210.200 – CHO cells MeSH A11.251.210.505 – l cells (cell line) MeSH A11.251...
    47 KB (3,940 words) - 16:46, 9 February 2024
  • Thumbnail for Monoamine releasing agent
    receptor agonists potentiate amphetamine-mediated dopamine efflux in PC12 cells in vitro (Izenwasser et al., 1998; Weatherspoon and Werling, 1999). These...
    263 KB (22,099 words) - 23:59, 9 May 2025
  • Thumbnail for DDR1
    Bradshaw RA (May 2000). "Discoidin domain receptor 1 (DDR1) signaling in PC12 cells: activation of juxtamembrane domains in PDGFR/DDR/TrkA chimeric receptors"...
    10 KB (1,207 words) - 19:16, 27 March 2024
  • Thumbnail for Valosin-containing protein
    control of endoplasmic reticulum in neuronally differentiated mammalian PC12 cells". The Journal of Biological Chemistry. 277 (49): 47358–65. doi:10.1074/jbc...
    49 KB (5,868 words) - 04:33, 6 January 2025
  • Thumbnail for Bafilomycin
    degradation of LC3-II. In PC12 cells, bafilomycin was found to induce apoptosis, or programmed cell death. Additionally, in some cell lines it has been found...
    40 KB (4,672 words) - 14:16, 10 September 2024