PC12 is a cell line derived from a pheochromocytoma of the rat adrenal medulla, that have an embryonic origin from the neural crest that has a mixture...
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PC12 may refer to: PC12 cell line, in biotechnology PC12 minicomputer Pilatus PC-12, a civilian aircraft BAP Río Chira (PC 12), a vessel of the Peruvian...
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calvarium) Rat tumor cell lines GH3 (pituitary tumor) PC12 (pheochromocytoma) Other mammal cell lines BHK21 cell (Baby Hamster Kidney) MDBK cell (Madin-Darby...
109 KB (8,502 words) - 21:10, 22 May 2025
SH-SY5Y (category Human cell lines)
SH-SY5Y is a human derived cell line used in scientific research. The original cell line, called SK-N-SH, from which it was subcloned was isolated from...
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and Borrego JJ. 1998. Neurotoxic effect on two fish species and a PC12 cell line of the supernate of Vibrio alginolyticus and Vibrio anguillarum. Veterinary...
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demonstrated that ALK activation promotes neuronal differentiation of PC12 or neuroblastoma cell lines. ALK is critical for embryonic development in Drosophila...
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progenitor cells. Moreover, when directly overexpressed in vivo in neural progenitor cells, BTG2 induces their differentiation. In fact, in the neuronal PC12 cell...
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GRB2 (category Cell signaling)
phosphatase to FRS2 is essential for fibroblast growth factor-induced PC12 cell differentiation". Molecular and Cellular Biology. 18 (7): 3966–73. doi:10...
82 KB (9,365 words) - 09:44, 2 March 2025
disruption of its GTPase activity promotes aberrant neurite sprouting in PC12 cells". NeuroReport. 14 (1): 31–7. doi:10.1097/00001756-200301200-00006. PMID 12544826...
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brain-specific Ras-related protein, activates Akt and promotes cell survival in PC12 cells". Oncogene. 19 (16): 2014–22. doi:10.1038/sj.onc.1203530. PMID 10803462...
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been shown to block the neuronal differentiation of rat pheochromocytoma PC12 cells by inhibition of trk tyrosine kinase activity. K252a has been reported...
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adhesion of neuron-like pc12 cells. Early cell adhesion is very important for preventing cell degeneration; the longer cells are suspended in culture...
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dopamine formed by monoamine oxidase (MAO). In differentiated neuronal cells of the PC12 line, physiological concentrations of DOPAL in isolated mitochondria...
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in permeabilized cells: This is based on the studies on permeabilized neurosecretory cells, such as chromaffin and PC12. These cells vesicle merging...
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peptide stimulation of G protein-mediated signaling in differentiated PC12 cells: identification of PACAP 6-38 as a CART receptor antagonist". Neuropeptides...
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Stress granule (category Cell biology)
(September 2006). "Oxidative stress reveals heterogeneity of FMRP granules in PC12 cell neurites". Brain Research. 1112 (1): 56–64. doi:10.1016/j.brainres.2006...
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differences in stimulus timing duration and dynamics. For example, treating PC12 cells with epidermal growth factor (EGF, inducing a transient profile of ERK...
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virus type-1 Tat protein activates phosphatidylinositol 3-kinase in PC12 neuronal cells". J. Biol. Chem. 271 (38): 22961–4. doi:10.1074/jbc.271.38.22961...
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Huttner WB (September 1983). "Tyrosine-O-sulfated proteins of PC12 pheochromocytoma cells and their sulfation by a tyrosylprotein sulfotransferase". J...
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Huntingtin disrupts growth factor receptor signaling in rat pheochromocytoma (PC12) cells". The Journal of Biological Chemistry. 277 (8): 6703–7. doi:10.1074/jbc...
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Murphy, C. J. (June 2005). "Cooperative modulation of neuritogenesis by PC12 cells by topography and nerve growth factor". Biomaterials. 26 (17): 3639–3644...
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Researchers have shown that PC12 cells treated with hydrogen peroxide (H2O2) as an oxidative stressor experience cell death due to apoptosis. When treated...
27 KB (3,000 words) - 11:53, 11 February 2025
peptide stimulation of G protein-mediated signaling in differentiated PC12 cells: identification of PACAP 6-38 as a CART receptor antagonist". Neuropeptides...
100 KB (8,956 words) - 14:28, 23 May 2025
PA, Südhof TC, Jahn R (Aug 1996). "Fatty acylation of synaptotagmin in PC12 cells and synaptosomes". Biochemical and Biophysical Research Communications...
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several neurodevelopmental processes in a neuronal cell line. PC12 cells showed decreased cell replication and growth, increased oxidative stress, and...
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210.190.750 – pc12 cells MeSH A11.251.210.190.880 – u937 cells MeSH A11.251.210.200 – CHO cells MeSH A11.251.210.505 – l cells (cell line) MeSH A11.251...
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receptor agonists potentiate amphetamine-mediated dopamine efflux in PC12 cells in vitro (Izenwasser et al., 1998; Weatherspoon and Werling, 1999). These...
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Bradshaw RA (May 2000). "Discoidin domain receptor 1 (DDR1) signaling in PC12 cells: activation of juxtamembrane domains in PDGFR/DDR/TrkA chimeric receptors"...
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control of endoplasmic reticulum in neuronally differentiated mammalian PC12 cells". The Journal of Biological Chemistry. 277 (49): 47358–65. doi:10.1074/jbc...
49 KB (5,868 words) - 04:33, 6 January 2025
degradation of LC3-II. In PC12 cells, bafilomycin was found to induce apoptosis, or programmed cell death. Additionally, in some cell lines it has been found...
40 KB (4,672 words) - 14:16, 10 September 2024