ligase PIAS3 is an enzyme that in humans is encoded by the PIAS3 gene. The mammalian PIAS family consists of four members: PIAS1, PIAS2, PIAS3 and PIAS4...
18 KB (2,265 words) - 20:40, 3 March 2023
mammalian PIAS family are encoded by four genes: PIAS1, PIAS2 (PIASx), PIAS3, and PIAS4 (PIASy). Apart from PIAS1, each gene encodes two protein isoforms...
29 KB (3,175 words) - 21:59, 29 May 2025
in association with MITF. PIAS3 is a transcriptional inhibitor that acts by inhibiting STAT3's DNA binding activity. PIAS3 directly interacts with MITF...
43 KB (4,822 words) - 08:33, 21 October 2024
enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB...
15 KB (1,777 words) - 07:49, 20 May 2025
enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB...
29 KB (3,502 words) - 12:50, 3 March 2025
enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB...
33 KB (3,238 words) - 16:28, 25 May 2025
enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB...
76 KB (8,708 words) - 09:25, 13 March 2025
enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB...
49 KB (5,534 words) - 15:15, 2 May 2025
enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB...
34 KB (4,010 words) - 17:12, 19 August 2024
HERC4, HERC5, HERC6 HUWE1, ITCH NEDD4, NEDD4L PPIL2 PRPF19 PIAS1, PIAS2, PIAS3, PIAS4 RANBP2 RNF4, RNF167 RBX1 SMURF1, SMURF2 STUB1 TOPORS TRIP12 UBE3A...
40 KB (4,436 words) - 07:10, 2 June 2025
signaling dynamics. PIAS are a four-member protein family made of: PIAS1, PIAS3, PIASx, and PIASγ. The proteins add a marker, called SUMO (small ubiquitin-like...
62 KB (6,845 words) - 06:02, 23 May 2025
enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB...
53 KB (6,405 words) - 14:47, 8 June 2025
PBX1 (1q23) PEA15 (1q23) PGDB5: PiggyBac transposable element derived 5 PIAS3 (1q21) PI4KB: Phosphatidylinositol 4-kinase beta PIP5K1A (1q21):...
47 KB (3,307 words) - 21:26, 10 June 2025
enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB...
11 KB (1,152 words) - 17:58, 25 May 2025
enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB...
101 KB (11,338 words) - 19:50, 22 April 2025
enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB...
4 KB (503 words) - 11:16, 4 March 2023
proximal area are HFE2, TXNIP, POLR3GL, LIX1L, RBM8A, PEX11B, ITGA10, ANKRD35, PIAS3, NUDT17, POLR3C, RNF115, CD160, PDZK1, and GPR89A.[citation needed] Genes...
6 KB (840 words) - 17:41, 30 May 2025
Smad transcriptional activity by protein inhibitor of activated STAT3 (PIAS3)". Proc. Natl. Acad. Sci. U.S.A. 101 (1): 99–104. Bibcode:2004PNAS..101...
20 KB (2,408 words) - 09:49, 13 January 2025
enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB...
22 KB (2,320 words) - 09:55, 22 May 2025
MTPN, NCF1, NFKB1, NFKB2, NFKBIB, NFKBIE, NR3C1, NCOR2, PARP1, PDLIM2, PIAS3, PIM1, PIN1, PKA, POU2F1, PPARG, PPP1R13L, PRKCZ, REL, RFC1, RNF25, SIRT1...
56 KB (6,507 words) - 07:54, 19 July 2024
enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB...
5 KB (614 words) - 06:16, 2 November 2024
enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB...
21 KB (2,321 words) - 14:33, 9 June 2025
2006.02.034. PMID 16797877. Iwasaki K, Hailemariam K, Tsuji Y (2007). "PIAS3 interacts with ATF1 and regulates the human ferritin H gene through an...
8 KB (1,006 words) - 01:24, 13 August 2023
enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB...
31 KB (3,599 words) - 03:24, 2 June 2025
enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB...
51 KB (5,551 words) - 22:14, 23 April 2025
enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB...
5 KB (650 words) - 14:32, 17 February 2025
chemotherapeutic agent for solid tumors. HMGA2 has been shown to interact with PIAS3 and NFKB1. The transport of HMGA2 to the nucleus is mediated by an interaction...
24 KB (2,916 words) - 09:09, 5 February 2025
enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB...
40 KB (4,909 words) - 18:03, 25 May 2025
enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB...
51 KB (5,785 words) - 23:20, 15 May 2025
enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB...
10 KB (1,253 words) - 03:46, 28 October 2022