• Platelet-activating factor, also known as PAF, PAF-acether or AGEPC (acetyl-glyceryl-ether-phosphorylcholine), is a potent phospholipid activator and...
    16 KB (1,930 words) - 01:51, 11 December 2023
  • Thumbnail for Platelet-derived growth factor
    Platelet-derived growth factor (PDGF) is one among numerous growth factors that regulate cell growth and division. In particular, PDGF plays a significant...
    24 KB (2,882 words) - 15:04, 24 May 2025
  • Thumbnail for Platelet-activating factor receptor
    The platelet-activating factor receptor (PAF-R) is a G-protein coupled receptor which binds platelet-activating factor. It is encoded in the human by the...
    9 KB (1,097 words) - 22:30, 27 March 2024
  • Thumbnail for Coagulation
    vessel wall). Activation of platelets and platelet plug formation: Platelet activation: Platelet activators, such as platelet activating factor and thromboxane...
    64 KB (6,646 words) - 08:40, 9 June 2025
  • Thumbnail for Rupatadine
    Rupatadine is a second generation antihistamine and platelet-activating factor antagonist used to treat allergies. It was discovered and developed by Uriach [es]...
    9 KB (644 words) - 18:11, 14 June 2025
  • Thumbnail for Platelet factor 4
    Platelet factor 4 (PF4) is a small cytokine belonging to the CXC chemokine family that is also known as chemokine (C-X-C motif) ligand 4 (CXCL4) . This...
    14 KB (1,641 words) - 23:08, 5 September 2024
  • born in Paris. In 1979, he published a paper on the structure of platelet-activating factor and its relationship with histamine. He was head of allergy and...
    30 KB (3,160 words) - 18:56, 22 May 2025
  • Thumbnail for Platelet
    (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping to form a blood clot. Platelets have no cell nucleus; they...
    71 KB (8,529 words) - 20:44, 19 June 2025
  • Thumbnail for Lipoprotein-associated phospholipase A2
    Lipoprotein-associated phospholipase A2 (Lp-PLA2) also known as platelet-activating factor acetylhydrolase (PAF-AH) is a phospholipase A2 enzyme that in...
    12 KB (1,378 words) - 21:36, 20 September 2024
  • Thumbnail for Ether lipid
    (MAGEs) are also generated from 2-acetyl MAGEs (precursors of platelet-activating factor) by KIAA1363. Plasmalogens as well as some 1-O-alkyl lipids are...
    13 KB (1,497 words) - 04:54, 14 June 2025
  • Thumbnail for Clotizolam
    and muscle relaxant effects, and also acts as an inhibitor of platelet-activating factor (PAF). Brotizolam Etizolam Flubrotizolam Fluclotizolam Deschloroclotizolam...
    3 KB (123 words) - 19:29, 11 January 2025
  • Thumbnail for PAFAH1B1
    Platelet-activating factor acetylhydrolase IB subunit alpha or Lisencephaly protein-1 (LIS-1) is an enzyme that in humans is encoded by the PAFAH1B1 gene...
    13 KB (1,513 words) - 22:27, 25 May 2025
  • Thumbnail for Israpafant
    (Y-24180) is a drug which acts as a selective antagonist for the platelet-activating factor receptor, and was originally developed for the treatment of asthma...
    5 KB (479 words) - 13:27, 19 December 2023
  • developed to treat severe sepsis. Pafase is the recombinant form of platelet-activating factor acetylhydrolase (PAF-AH, also known as lipoprotein-associated...
    44 KB (4,452 words) - 21:08, 29 May 2025
  • In enzymology, a platelet-activating factor acetyltransferase (EC 2.3.1.149) is an enzyme that catalyzes the chemical reaction 1-alkyl-2-acetyl-sn-gly...
    2 KB (199 words) - 15:29, 26 August 2023
  • extension of PortableApps files Paroxysmal atrial fibrillation Platelet-activating factor Population attributable fraction (epidemiology) Pure autonomic...
    2 KB (202 words) - 05:41, 5 December 2023
  • Thumbnail for Apafant
    a potent and selective inhibitor of the phospholipid mediator platelet-activating factor (PAF). It was developed by structural modification of the...
    3 KB (258 words) - 19:51, 7 September 2024
  • Thumbnail for B-cell activating factor
    danger activating thrifty genes in order to store fat and to avoid starvation. BAFF shares many activities with PAF (Platelet Activating Factor) and they...
    25 KB (3,095 words) - 14:05, 12 March 2024
  • as platelet-activating factor. There are multiple enzymes with this function: Lipoprotein-associated phospholipase A2 Platelet-activating factor acetylhydrolase...
    2 KB (225 words) - 16:21, 22 September 2024
  • Thumbnail for Retrograde signaling
    identity generated a list of candidates including carbon monoxide, platelet-activating factor, arachidonic acid, and nitric oxide. Nitric oxide has received...
    26 KB (3,056 words) - 21:11, 23 May 2025
  • encoding the alpha subunit of the intracellular Ib isoform of platelet-activating factor acetylhydrolase. It is located on chromosome 17p13.3 and has 11...
    19 KB (2,375 words) - 13:15, 25 July 2024
  • Thumbnail for Ginkgolide
    class of molecules has been studied for its potential to act as a platelet-activating factor receptor antagonist. Ginkgolide B has been investigated for its...
    7 KB (750 words) - 06:51, 28 May 2025
  • Thumbnail for Hexadecane
    and hydrogels, and for positron emission tomography. Hexadecyl platelet-activating factor has profound effects on the lung, and hexadecyl glyceryl ether...
    8 KB (590 words) - 03:03, 12 May 2025
  • Thumbnail for Lipid signaling
    primarily by activation of ceramidase by growth-inducing proteins such as platelet-derived growth factor and insulin-like growth factor, is consistent...
    55 KB (5,633 words) - 08:40, 12 July 2024
  • Thumbnail for PAFAH2
    substrate specificity than simply platelet activating factor. Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist, and both...
    5 KB (583 words) - 19:49, 8 April 2022
  • Thumbnail for Immunoglobulin G
    receptor FcεRI, stimulating the release of both histamine and platelet activating factor (PAF). In the alternative pathway, antigens form complexes with...
    18 KB (2,098 words) - 05:56, 18 June 2025
  • Thumbnail for Vasodilation
    causing degranulation. Granules in these cells contain histamine, platelet-activating factor, and other compounds causing clinical manifestation of anaphylaxis-...
    44 KB (4,096 words) - 22:53, 25 October 2024
  • Thumbnail for Arrestin beta 2
    internalization of the platelet-activating factor receptor is dependent on arrestins but independent of G-protein activation. Role of the C terminus...
    17 KB (1,965 words) - 15:27, 31 December 2024
  • Thumbnail for Mastocytoma
    tissue trauma. Mast cell granules contain histamine, heparin, platelet-activating factor, and other substances. Disseminated mastocytosis is rarely seen...
    19 KB (2,282 words) - 21:26, 29 May 2025
  • Thumbnail for GroES
    GroES (redirect from Early pregnancy factor)
    C, Perkins T, Clarke FM (Nov 1986). "Platelet-activating factor induces the expression of early pregnancy factor activity in female mice". Journal of...
    34 KB (4,108 words) - 02:42, 22 November 2024