The proton-coupled folate transporter is a protein that in humans is encoded by the SLC46A1 gene. The major physiological roles of PCFTs are in mediating...
22 KB (2,649 words) - 18:32, 9 June 2024
and then transport across the brush border membrane by the proton-coupled folate transporter (SLC46A1). Diffuse inflammatory or degenerative diseases of...
29 KB (3,176 words) - 17:31, 16 January 2025
Hereditary folate malabsorption (HFM) is a rare autosomal recessive disorder caused by loss-of-function mutations in the proton-coupled folate transporter (PCFT)...
26 KB (2,754 words) - 15:32, 12 October 2024
"The proton-coupled folate transporter (PCFT-SLC46A1) and the syndrome of systemic and cerebral folate deficiency of infancy: Hereditary folate malabsorption"...
16 KB (1,334 words) - 13:52, 24 May 2025
absorption is primarily accomplished by the action of the proton-coupled folate transporter (PCFT) protein coded for by the SLC46A1 gene. This functions...
107 KB (11,361 words) - 20:53, 29 May 2025
Proton-coupled amino acid transporter 2 is a protein which in humans is encoded by the SLC36A2 gene. SLC36A2 transports small amino acids (glycine, alanine...
4 KB (468 words) - 01:28, 27 May 2025
Monocarboxylate transporter 1 is a ubiquitous protein that in humans is encoded by the SLC16A1 gene (also known as MCT1). It is a proton coupled monocarboxylate...
12 KB (1,379 words) - 02:23, 9 May 2025
Solute carrier family (redirect from Sodium-dependent organic anion transporter)
(SLC10A1, SLC10A2, SLC10A3, SLC10A4, SLC10A5, SLC10A6, SLC10A7) proton coupled metal ion transporter (SLC11A1, SLC11A2) electroneutral cation-Cl cotransporter...
35 KB (3,408 words) - 02:42, 30 November 2023
regulating the concentrations of substances within them. Vesicular transporters rely on a proton gradient created by the hydrolysis of adenosine triphosphate...
9 KB (988 words) - 08:33, 25 May 2025
Sodium-coupled monocarboxylate transporter 1 (i.e., SMCT1) and sodium-coupled monocarboxylate transporter 2 (i.e., SMCT2) are plasma membrane transport...
53 KB (6,958 words) - 05:48, 26 January 2025
cancer. HCP1 is also known as proton-coupled folate transporter (PCFT), as it was initially identified as a transporter for folate, a type of vitamin B However...
12 KB (1,428 words) - 18:07, 13 February 2024
Antiporter (section Reduced folate carrier protein)
human reduced folate carrier/ThTr1 thiamine transporter chimaeras: role of the transmembrane domain 6/7 linker region in reduced folate carrier function"...
60 KB (7,840 words) - 00:16, 11 February 2025
Folate Carrier (RFC) Family 2.A.49 Chloride Carrier/Channel (ClC) Family 2.A.50 The Glycerol Uptake (GUP) Family 2.A.51 The Chromate Ion Transporter (CHR)...
38 KB (5,159 words) - 15:41, 17 April 2024
up its concentration gradient but the coupled molecule is transported in the opposite direction. Ion transporters can be regulated in a variety of different...
17 KB (2,039 words) - 15:51, 25 May 2025
Folate transporter 1 is a protein which in humans is encoded by the SLC19A1 gene. Transport of folate compounds into mammalian cells can occur via receptor-mediated...
11 KB (1,281 words) - 20:23, 22 May 2025
Proton-coupled amino acid transporter 1 is a protein that in humans is encoded by the SLC36A1 gene. This gene encodes a member of the eukaryote-specific...
6 KB (769 words) - 03:17, 1 January 2024
thienoyl antifolate inhibitor with proton-coupled folate transporter and folate receptor selectivity over the reduced folate carrier that inhibits β-glycinamide...
25 KB (2,838 words) - 19:16, 23 November 2024
(2004). "Biophysical evidence for His57 as a proton-binding site in the mammalian intestinal transporter hPepT1". Pharm. Res. 20 (12): 1911–6. doi:10...
8 KB (935 words) - 13:52, 8 April 2024
The mitochondrial folate transporter (MTF) is a transport protein that facilitates the transfer of tetrahydrofolate across the inner mitochondrial membrane...
4 KB (385 words) - 16:08, 12 February 2025
The Vesicular acetylcholine transporter (VAChT) is a neurotransmitter transporter which is responsible for loading acetylcholine (ACh) into secretory...
7 KB (823 words) - 10:03, 27 March 2024
Membrane transport protein (redirect from Membrane transporter)
atypical SLCs are secondary active or facilitative transporters in humans. Collectively membrane transporters and channels are known as the transportome. Transportomes...
26 KB (2,656 words) - 14:08, 8 March 2025
miscarriage, neural tube defects, and developmental delays in offspring. Folate levels may modify the presentation of symptoms and disease course. Vitamin...
111 KB (11,959 words) - 22:32, 29 May 2025
Sodium-coupled monocarboxylate transporter 2 (i.e., SMCT2, also termed SLC5A12) is a plasma membrane transport protein in the solute carrier family. It...
17 KB (2,097 words) - 19:08, 13 July 2024
Glucose transporters are a wide group of membrane proteins that facilitate the transport of glucose across the plasma membrane, a process known as facilitated...
16 KB (1,327 words) - 21:12, 2 October 2024
The serotonin transporter (SERT or 5-HTT) also known as the sodium-dependent serotonin transporter and solute carrier family 6 member 4 is a protein that...
31 KB (3,442 words) - 04:14, 20 May 2025
Sodium–hydrogen antiporter (redirect from Sodium–proton antiporter)
The sodium–hydrogen antiporter or sodium–proton exchanger (Na+/H+ exchanger or NHX) is a membrane protein that transports Na+ into the cell, and H+ out...
6 KB (670 words) - 09:42, 14 May 2024
Cotransporters are a subcategory of membrane transport proteins (transporters) that couple the favorable movement of one molecule with its concentration...
22 KB (2,275 words) - 14:55, 28 May 2025
The organic anion transporter 1 (OAT1) also known as solute carrier family 22 member 6 (SLC22A6) is a protein that in humans is encoded by the SLC22A6...
22 KB (2,503 words) - 02:45, 25 May 2025
and potassium coupled glutamate transporters'. Na+-dependent transporters have also been called 'high-affinity glutamate transporters', though their...
24 KB (2,828 words) - 15:14, 24 September 2023
Weihe E, Schütz B (February 2004). "The vesicular amine transporter family (SLC18): amine/proton antiporters required for vesicular accumulation and regulated...
29 KB (3,347 words) - 14:46, 25 May 2025