Synaptic pruning is the process of synapse elimination or weakening. Though it occurs throughout the lifespan of a mammal, the most active period of synaptic...

individual's critical period, during which there is a certain degree of synaptic pruning due to competition for neural growth factors by neurons and synapses...

biological process of synaptic pruning which takes place in mammalian brains during development. A basic algorithm for pruning is as follows: Evaluate...

the brain follows an inverted-U pattern. Through a process called synaptic pruning, unnecessary neuronal connections in the brain are eliminated and the...

receptors, downregulation of this inhibitory receptor may increase global synaptic pruning activity. While difference in expression or distribution is observed[citation...

how pruning is used in vine training systems Synaptic pruning, the reformation of neural structure by pruning "excess" neurons or neural clusters This disambiguation...

neurons competing for connections). Microglia inherently play a role in synaptic pruning during adolescence. As resident immune cells of the central nervous...

regulate behavior and engage in inhibitory control. As a result of synaptic pruning and myelination of the prefrontal cortex, improvements in executive...

identify the role of microglia and complement proteins in the "pruning" or removal of synaptic cells during brain development, and has also determined that...

generation of synapses between axons and their postsynaptic partners. The synaptic pruning that occurs in adolescence. The lifelong changes in synapses which...

scaffold proteins, while pruning less active ones. For example, cell adhesion molecules (CAMs) play a large role in synaptic maintenance and stabilization...

phenomenon is a result of neuroplasticity, including Hebbian learning and synaptic pruning. Through these mechanisms, neural pathways that are more consistently...

anti-anxiety activity. GABAA receptors participate in the regulation of synaptic pruning by prompting microglial spine engulfment. Benzodiazepines have been...

cortex. These disruptions often occur during development linked with synaptic pruning dysfunction. People with bipolar disorder who are in a euthymic mood...

plaques and neurofibrillary tangles, as well as neuronal cell death and synaptic pruning. The principle drug treatments on the market deal with antagonizing...

most cells were unused, then this technique would have revealed that. Synaptic pruning: Brain cells that are not used have a tendency to degenerate. Hence...

combination of the occurrence of critical neuronal development and synaptic pruning of brain regions important for social behavior and environmental changes...

pruning of unused connections in thinking and processing. While this is occurring within the brain, retained connections are strengthened. Synaptic pruning...

affect organizational processes of the brain such as neurogenesis, synaptic pruning, cell migration and cellular differentiation. This thus results in...

proteins of the classical complement pathway have an important role in synaptic pruning in the brain during early development. Janeway Jr CA, Travers P, Walport...

tissue. Microglia and the complement system are also associated with synaptic pruning as their secretions of cytokines, growth factors and other complements...

non-rapid eye movement sleep (NREM), and the impact sleep has on "synaptic pruning" and the creation of memories during a human's lifespan are also covered...

of high SES demonstrated a steeper linear decline, suggesting that synaptic pruning is more efficient in the latter group. This trend was especially evident...

neurophysiological changes like slowed myelination, abnormalities in synaptic pruning, shrinking of the hippocampus, cognitive and affective impairment....

the possibility that there is deregulation of GSK3β resulting in 'synaptic pruning'. If there is excess removal of synapses, this illustrates early signs...

formed in excess, and experience and activity may lead to the pruning of extraneous synaptic connections. In lab animals of all ages, environmental enrichment...

the pruning hypothesis, which states that synesthesia is common in early childhood but diminishes throughout development through synaptic pruning. The...

has also been shown that microglia are involved in the process of synaptic pruning during brain development. Post-inflammation, microglia undergo several...

neuro-developmental process of maturation. It is possible that incomplete synaptic pruning during childhood development could lead to the continued maintenance...

individuals, these connections are eliminated through a process known as synaptic pruning, which refines and specializes neural circuits during early development...