Synaptic stabilization is crucial in the developing and adult nervous systems and is considered a result of the late phase of long-term potentiation (LTP)...

the synaptic neurons, responding to synaptic activity and, in turn, regulating neurotransmission. Synapses (at least chemical synapses) are stabilized in...

that form a synaptic association, and is specific to the stimulated pathway of synaptic transmission. The long-term stabilization of synaptic changes is...

are specialized extracellular matrix structures responsible for synaptic stabilization in the adult brain. PNNs are found around certain neuron cell bodies...

other genes thought to be involved in LTP, dendritogenesis, and synaptic stabilization. NMDA receptor activation is essential to producing the activity-dependent...

propagate along the axon, leading to release of neurotransmitters at the synaptic bouton to pass along information to yet another adjacent neuron. Synthesis...

cadherins implicates these molecules as major players in the process of synaptic stabilization. Each cadherin exhibits a unique pattern of tissue distribution...

interaction between them in the maintenance of L-LTP. The long-term stabilization of synaptic changes is also determined by a parallel increase of pre- and...

plasticity mechanisms modify neural synaptic connections selectively, synaptic scaling normalizes all neural synaptic connections by decreasing the strength...

The first, synaptic consolidation, which is thought to correspond to late-phase long-term potentiation, occurs on a small scale in the synaptic connections...

Besides this, N-cadherin also plays a role in the maturation and stabilization of synaptic specializations. Lastly, N-cadherins help to control dendritic...

The active zone or synaptic active zone is a term first used by Couteaux and Pecot-Dechavassinein in 1970 to define the site of neurotransmitter release...

synaptic vesicles, triggering vesicle fusion with the cell membrane and subsequent neurotransmitter release from the motor neuron into the synaptic cleft...

Tschida KA, Klein ME, Mooney R (February 2010). "Rapid spine stabilization and synaptic enhancement at the onset of behavioural learning". Nature. 463...

electric signal from the presynaptic neuron to the target cell through the synaptic gap. Neurons are the main components of nervous tissue in all animals except...

variations in synaptic input is known as homeostatic synaptic plasticity. Homeostatic synaptic plasticity occurs when neurons modify their synaptic strength...

plasticity (STDP) is a biological process that adjusts the strength of synaptic connections between neurons based on the relative timing of their action...

enhancement of synaptic strength (known as Long-term potentiation (LTP)) and proposed mechanisms that might contribute to allocation at the synaptic level include...

However, at synaptic sites— particularly the postsynaptic density (PSD)—this motion is modulated by retention forces that can transiently stabilize receptors...

Synaptic tagging, or the synaptic tagging hypothesis, has been proposed to explain how neural signaling at a particular synapse creates a target for subsequent...

Heterosynaptic plasticity is a subtype of synaptic plasticity, referring to a chemical synapse's ability to undergo changes in strength, or efficacy of...

postsynaptic muscle cell. It stabilizes the postsynaptic acetylcholine receptor clusters, facilitates the transcription of synaptic genes by muscle fiber nuclei...

potassium channels. It plays an important role in synaptic plasticity and the stabilization of synaptic changes during long-term potentiation. PSD-95 (encoded...

long-term potentiation (LTP), a well-studied form of synaptic plasticity, and consists of an increase in synaptic strength. LTP could be produced by repetitive...

The most major effect a mutation could have is on synaptic stabilization. Since the gene limits synaptic plasticity, a mutation may cause issues in proper...

where it provides microtubule stabilization but also flexibility as needed. Tau proteins interact with tubulin to stabilize microtubules and promote tubulin...

the SNCA gene. It is a neuronal protein involved in the regulation of synaptic vesicle trafficking and the release of neurotransmitters. Alpha-synuclein...

selectively weaken specific synapses in order to make constructive use of synaptic strengthening caused by LTP. This is necessary because, if allowed to continue...

this stabilization increases the likelihood that released glutamate will bind receptors on the postsynaptic neuron. At basal levels of synaptic activity...

lysosome). The best studied SNAREs are those that mediate the release of synaptic vesicles containing neurotransmitters in neurons. These neuronal SNAREs...