Syntaxins are a family of membrane integrated Q-SNARE proteins participating in exocytosis. Syntaxins possess a single C-terminal transmembrane domain...
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SNARE protein (section Syntaxin and the Habc domain)
clasp releases closed syntaxin, remains associated with the N-terminal peptide of syntaxin (allowing association of the syntaxin SNARE domain with other...
54 KB (6,597 words) - 21:12, 11 July 2025
STX1A (redirect from Syntaxin 1A)
presynaptic active zone. Syntaxins function in this vesicle fusion process. Syntaxin-1A is a member of the syntaxin superfamily. Syntaxins are nervous system-specific...
26 KB (2,987 words) - 07:24, 19 July 2025
STX6 (redirect from Syntaxin 6 N terminal protein domain)
Syntaxin-6 is a protein that in humans is encoded by the STX6 gene. STX6 has been shown to interact with SNAP23, VAMP3 and VAMP4. The protein domain Syntaxin...
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Syntaxin-binding protein 1 (also known as Munc18-1) is a protein that in humans is encoded by the STXBP1 gene. This gene encodes a syntaxin-binding protein...
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Syntaxin 3, also known as STX3, is a protein which in humans is encoded by the STX3 gene. The protein encoded by this gene is a member of the syntaxin...
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STX2 (redirect from Syntaxin-2)
Syntaxin-2, also known as epimorphin, is a protein that in humans is encoded by the STX2 gene. The product of this gene belongs to the syntaxin/epimorphin...
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Syntaxin-binding protein 3 is a protein that in humans is encoded by the STXBP3 gene. Syntaxin binding protein 3 has been shown to interact with STX2 and...
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family, and syntaxin-1 also help form the SNARE complex by each contributing a single α-helix. SNAP-25 assembles with synaptobrevin and syntaxin-1, and the...
45 KB (5,006 words) - 08:04, 25 March 2024
Syntaxin-binding protein 2 is a protein that in humans is encoded by the STXBP2 gene. GRCh38: Ensembl release 89: ENSG00000076944 – Ensembl, May 2017 GRCm38:...
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Syntaxin-binding protein 5 is a protein that in humans is encoded by the STXBP5 gene. It is also known as tomosyn, after 友, "friend" in Japanese, for its...
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Some of the first proteins identified as the receptors of SNAPs were syntaxin 1, SNAP-25 (synaptosome associated protein, 25kDa), and VAMP (synaptobrevin)...
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fusion protein and alpha-SNAP induce a conformational change in syntaxin". The Journal of Biological Chemistry. 270 (28): 16955–61. doi:10.1074/jbc...
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Syntaxin-4 is a protein that in humans is encoded by the STX4 gene. STX4 has been shown to interact with: Gelsolin, NAPA, RAB4A, SNAP-25, SNAP23, STXBP1...
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intermediate complex composed of SNAP-25 and syntaxin-1, which later accommodates synaptobrevin-2 (the quoted syntaxin and synaptobrevin isotypes participate...
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in this event. Munc13 is thought to stimulate the change of the t-SNARE syntaxin from a closed conformation to an open conformation, which stimulates the...
34 KB (3,981 words) - 12:36, 24 May 2025
exocytosis of neurons and neuroendocrine cells. Munc-18 binds syntaxin and forms a syntaxin/munc-18 complex which is thought to precede and/or regulate...
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synaptotagmin and mediated by SNARE proteins. SNARE complex is formed by syntaxin-1 and SNAP25 at the presynaptic plasma membrane and Synaptrobrevin (VAMP)...
19 KB (2,200 words) - 04:03, 9 June 2025
Syntaxin-10 (STX10) is a SNARE protein that is encoded by the STX10 gene. This protein is found in most vertebrates (including humans) but is noticeably...
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serotype B, D, F and G cut synaptobrevin. Serotype C cleaves both SNAP-25 and syntaxin. This causes blockade of neurotransmitter acetylcholine release, ultimately...
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Syntaxin-8 is a protein that in humans is encoded by the STX8 gene. Syntaxin 8 directly interacts with HECTd3 and has similar subcellular localization...
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independently of the SNARE motif's functionality, and binds to clustered syntaxin. Studies of complex organelles, like mitochondria, also benefit from STED...
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FHL2: PRF1 (Perforin) FHL3: UNC13D (Munc13-4) FHL4: STX11 (Syntaxin 11) FHL5: STXBP2 (Syntaxin binding protein 2)/UNC18-2 Nearly half of the cases of type...
33 KB (3,699 words) - 01:08, 30 June 2025
p115/TAP, alpha-SNAP (this protein), gamma-SNAP, and the t-SNAREs syntaxin-2 and syntaxin-4, that are used in many vesicular transport processes in other...
12 KB (1,551 words) - 05:31, 15 January 2024
PMID 11780052. Prekeris R, Klumperman J, Chen YA, Scheller RH (1998). "Syntaxin 13 mediates cycling of plasma membrane proteins via tubulovesicular recycling...
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Syntaxin 11, also known as STX11, is a human gene that is a member of the t-SNARE family. STX11 has been shown to interact with SNAP25 and SNAP23. Hemophagocytic...
8 KB (1,063 words) - 07:24, 19 July 2025
Syntaxin-12 is a protein that in humans is encoded by the STX12 gene. STX12 has been shown to interact with PLDN. GRCh38: Ensembl release 89: ENSG00000117758...
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individual sympathetic varicosities, delineated by a high concentration of syntaxin, occupies an area on the pre-junctional membrane of about 0.2 μm2; this...
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protein Maltose-binding protein Phosphatidylethanolamine binding protein 1 Syntaxin binding protein 3 Insulin-like growth factor-binding protein Methyl-CpG-binding...
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(2004). "Syntabulin is a microtubule-associated protein implicated in syntaxin transport in neurons". Nat. Cell Biol. 6 (10): 941–53. doi:10.1038/ncb1169...
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