• Thumbnail for Telomerase RNA component
    Telomerase RNA component, also known as TR, TER or TERC, is an ncRNA found in eukaryotes that is a component of telomerase, the enzyme used to extend telomeres...
    23 KB (2,553 words) - 22:29, 10 December 2023
  • Thumbnail for Telomerase reverse transcriptase
    the telomerase RNA component (TERC), comprises the most important unit of the telomerase complex. Telomerases are part of a distinct subgroup of RNA-dependent...
    46 KB (5,303 words) - 08:02, 3 June 2024
  • Thumbnail for Telomerase
    each of human telomerase reverse transcriptase (TERT), Telomerase RNA Component (TR or TERC), and dyskerin (DKC1). The genes of telomerase subunits, which...
    49 KB (5,644 words) - 06:05, 27 April 2024
  • Thumbnail for Dyskeratosis congenita
    assembly and maturation of human telomerase RNA. Nonetheless, mutations that directly affect the telomerase RNA components would presumably exist and should...
    24 KB (2,732 words) - 18:09, 10 April 2024
  • Thumbnail for Carol W. Greider
    further test this idea mouse and human telomerase were characterized (1993) (1995) and the mouse telomerase RNA component was cloned (1995). During this time...
    31 KB (2,861 words) - 09:44, 17 April 2024
  • Thumbnail for Dyskerin
    58 kilo-daltons. Dyskerin is essential for the activity of telomerase by accumulating telomerase RNA component (TERC). This gene is a member of the H/ACA snoRNPs...
    9 KB (1,127 words) - 08:11, 13 April 2024
  • for the different types of RNA are listed and explained. List of cis-regulatory RNA elements RNA: Types of RNA Non-coding RNA Gribaldo S, Brochier-Armanet...
    20 KB (1,022 words) - 13:20, 22 February 2024
  • Thumbnail for RNA
    transfer RNA (tRNA), microRNA (miRNA), small interfering RNA (siRNA), small nucleolar RNA (snoRNAs), Piwi-interacting RNA (piRNA), tRNA-derived small RNA (tsRNA)...
    64 KB (7,522 words) - 14:14, 6 June 2024
  • Thumbnail for Telomeric repeat–containing RNA
    complementary RNA template region of telomerase. The complementary base pairing of the TERRA transcript may work to compete with telomerase's DNA substrate...
    35 KB (4,668 words) - 11:25, 11 February 2024
  • Thumbnail for Interstitial lung disease
    dysplasia (mutations in FoxF1) Mutations in telomerase reverse transcriptase (TERT) Mutations in telomerase RNA component (TERC) Mutations in the regulator of...
    28 KB (2,826 words) - 23:55, 30 April 2024
  • Thumbnail for Pseudoknot
    Pseudoknot (category RNA)
    The telomerase RNA component contains a pseudoknot that is critical for activity, and several viruses use a pseudoknot structure to form a tRNA-like...
    7 KB (808 words) - 18:32, 3 December 2023
  • Thumbnail for Non-coding RNA
    RNAs such as microRNAs, siRNAs, piRNAs, snoRNAs, snRNAs, exRNAs, scaRNAs and the long ncRNAs such as Xist and HOTAIR. The number of non-coding RNAs within...
    67 KB (7,214 words) - 06:02, 26 February 2024
  • Thumbnail for RNA world
    critical for life. One of the most critical components of cells, the ribosome, is composed primarily of RNA. Ribonucleotide moieties in many coenzymes...
    92 KB (10,688 words) - 16:09, 3 June 2024
  • Thumbnail for Long non-coding RNA
    ncRNAs from small non-coding RNAs, such as microRNAs (miRNAs), small interfering RNAs (siRNAs), Piwi-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs)...
    113 KB (12,225 words) - 22:11, 7 June 2024
  • snRNA component and several snRNP-specific proteins (including Sm proteins, a family of nuclear proteins). The most common human snRNA components of...
    17 KB (2,325 words) - 21:13, 1 February 2024
  • interfering RNA (siRNA) and micro RNA (miRNA) to prevent mRNA translation and/or degrade mRNA. However, RNA aptamers are short, single stranded RNA molecules...
    77 KB (8,886 words) - 09:03, 10 June 2024
  • Thumbnail for RNA-dependent RNA polymerase
    are ancestral to human telomerase. The most famous example of RdRp is that of the polio virus. The viral genome is composed of RNA, which enters the cell...
    28 KB (3,249 words) - 10:55, 3 June 2024
  • snoRNA to the single hairpin snoRNAs however, unlike trypanosomes, it has a regular ACA motif at 3′ tail.[19] The RNA component of human telomerase (hTERC)...
    31 KB (3,791 words) - 13:33, 9 January 2024
  • strand. Telomerase was shown to be a ribonucleoprotein enzyme that contains an RNA component that serves as a template strand, and a protein component that...
    41 KB (4,630 words) - 22:37, 1 June 2024
  • Thumbnail for Transcription (biology)
    contain an enzyme with reverse transcription activity called telomerase. Telomerase carries an RNA template from which it synthesizes a telomere, a repeating...
    58 KB (6,780 words) - 04:35, 23 May 2024
  • Thumbnail for Telomere
    Telomere (section Telomerase)
    Weinrich SL, Avilion AA, Chiu CP, et al. (September 1995). "The RNA component of human telomerase". Science. 269 (5228): 1236–41. Bibcode:1995Sci...269.1236F...
    43 KB (4,840 words) - 12:55, 29 February 2024
  • Thumbnail for Cajal body
    associated with telomerase assembly and recruitment via a CAB-RNA sequence common in both CB RNAs (scaRNAs) and the RNA component of telomerase (TERC). TCAB1...
    8 KB (1,020 words) - 17:32, 25 April 2024
  • While working at Geron Corporation, Andrews co-discovered the RNA component of human telomerase (hTR). For this discovery, Andrews was awarded second place...
    8 KB (735 words) - 17:14, 9 June 2024
  • Thumbnail for Nucleic acid structure
    DNA or RNA. Nucleotides consist of 3 components: Nitrogenous base Adenine Guanine Cytosine Thymine (present in DNA only) Uracil (present in RNA only) 5-carbon...
    18 KB (2,416 words) - 19:08, 15 April 2024
  • Thumbnail for Nucleic acid secondary structure
    biological processes rely on RNA molecules that form pseudoknots. For example, the RNA component of the human telomerase contains a pseudoknot that is...
    18 KB (2,194 words) - 07:26, 3 December 2023
  • Thumbnail for María Blasco Marhuenda
    "Functional characterization and developmental regulation of mouse telomerase RNA component". Science. 269 (5228): 1267–1270. doi:10.1126/science.7544492....
    12 KB (1,303 words) - 06:52, 26 October 2023
  • TERC may refer to: Telomerase RNA component, a human gene. TERC (Cambridge, Massachusetts), a nonprofit research and development organization in Cambridge...
    973 bytes (144 words) - 12:31, 15 January 2022
  • Thumbnail for Polysomy
    in situ hybridization test, detects amplification of the human telomerase RNA component (TERC) gene and/or polysomy of chromosome 3. Spectral karyotyping...
    39 KB (4,295 words) - 19:58, 17 April 2024
  • Thumbnail for Hayflick limit
    (6): 1496–1499. PMID 5158754. Feng F; et al. (1995). "The RNA component of human telomerase". Science. 269 (5228): 1236–1241. Bibcode:1995Sci...269.1236F...
    16 KB (1,873 words) - 07:38, 10 June 2024
  • Thumbnail for Poly(A)-specific ribonuclease
    "Poly(A)-specific ribonuclease (PARN) mediates 3'-end maturation of the telomerase RNA component". Nature Genetics. 47 (12): 1482–8. doi:10.1038/ng.3423. PMC 4791094...
    11 KB (1,338 words) - 19:41, 9 April 2024