U.S. Route 72 (US 72) is an east–west United States highway that travels for 317.811 miles (511.467 km) from southwestern Tennessee, throughout North Mississippi...

Alternate U.S. Route 72 (US 72 Alt.) exists in Alabama on the south side of the Tennessee River between Muscle Shoals and Decatur, while US 72 follows on...

Route 72 Alternate in Decatur, and U.S. Route 72 in Athens. Given US 31's former importance as a major connecting route in Alabama, in several cities it...

U.S. Route 45 (US 45) is a major north-south United States highway and a border-to-border route, from Lake Superior to the Gulf of Mexico. A sign at the...

U.S. Route 54 (US 54) is an east–west United States Highway that runs northeast–southwest for 1,197 miles (1,926 km) from El Paso, Texas, to Griggsville...

U.S. Route 189 is a spur of U.S. Route 89. It currently runs for 322 miles (518 km) from Provo, Utah at Interstate 15 to Jackson, Wyoming. The highway...

U.S. Route 36 (US 36) is an east–west United States Numbered Highway that travels approximately 1,414 miles (2,276 km) from Rocky Mountain National Park...

U.S. Route 89 (US 89) is a north–south United States Numbered Highway with two sections, and one former section. The southern section runs for 848 miles...

U.S. Route 64 (US 64) is an east–west United States highway that runs for 2,281 miles (3,672 km) from Nags Head in eastern North Carolina to just southwest...

U.S. Route 150 (US 150) is a 571-mile (919 km) long northwest–southeast United States highway, signed as east–west. It runs from U.S. Route 6 outside...

U.S. Route 51 or U.S. Highway 51 (US 51) is a major south–north United States highway that extends 1,277 miles (2,055 km) from the western suburbs of New...

U.S. Route 93 (US 93) is a major north–south 1,359-mile (2,187 km) U.S. Numbered Highway in the western United States, that connects U.S. Route 60 (US 60)...

U.S. Route 66 or U.S. Highway 66 (US 66 or Route 66) was one of the original highways in the United States Numbered Highway System. It was established...

U.S. Route 61 or U.S. Highway 61 (U.S. 61) is a major United States highway that extends 1,400 miles (2,300 km) between New Orleans, Louisiana and the...

connects U.S. Route 62 U.S. Route 75 (US 62/US 75) in Henryetta with U.S. Route 64 (US 64) in Warner. The highway no longer meets the former route of its...

U.S. Route 231 (US 231) is a north–south U.S highway that is a parallel route of US 31. It runs for 912 miles (1,468 km) from St. John, Indiana, at US 41...

U.S. Route 79 (US 79) is a United States highway in the Southern United States. The route is officially considered and labeled as a north–south highway...

U.S. Route 71 or U.S. Highway 71 (US 71) is a major north–south United States highway that extends for over 1500 miles (2500 km) in the central United...

U.S. Route 277 (US 277, US-277) is a north–south United States Highway that is a spur route of U.S. Route 77. It no longer connects to its parent route...

State Route 72 (SR 72) is a state highway in the U.S. state of California. The route runs along Whittier Boulevard in the Los Angeles area from SR 39 in...

U.S. Route 501 (US 501) is a spur of U.S. Route 1. It runs 355 miles (571 km) from Buena Vista, Virginia at U.S. Route 60 to Myrtle Beach, South Carolina...

U.S. Route 310 (US 310) is a spur of historic U.S. Route 10, now Interstate 90. It runs for 108 miles (174 km) from Laurel, Montana, to Greybull, Wyoming...

U.S. Route 89A is a 91.74-mile (147.64 km) north–south auxiliary U.S. highway (though its actual direction of travel is more east–west) in southwestern...

U.S. Route 20 or U.S. Highway 20 (US 20) is an east–west United States Numbered Highway that stretches from the Pacific Northwest east to New England....

U.S. Route 43 (US 43) is a 410-mile-long (660 km) north–south United States Highway in the Southern states of Alabama and Tennessee. It travels from Prichard...

U.S. Route 321 (US 321) is a spur of U.S. Route 21. It runs for 516.9 miles (831.9 km) from Hardeeville, South Carolina to Lenoir City, Tennessee; with...

now US-95 to Fruitland, Idaho, where it reconnected with US-30. U.S. Route 95 Truck (US 95 Truck) was a 0.45-mile (0.72 km) long truck route of US 95 in...

U.S. Route 58 (US 58) is an east–west U.S. Highway that runs for 508 miles (818 km) from U.S. Route 25E just northwest of Harrogate, Tennessee, to U.S...

U.S. Route 11 or U.S. Highway 11 (US 11) is a major north–south United States Numbered Highway extending 1,645 miles (2,647 km) across the eastern U.S...

U.S. Route 491 (US 491) is a north–south U.S. Highway serving the Four Corners region of the United States. It was created in 2003 as a renumbering of...