Apremilast, sold under the brand name Otezla among others, is a medication for the treatment of certain types of psoriasis and psoriatic arthritis. The...
23 KB (1,923 words) - 20:22, 31 May 2025
natural killer cells to kill T cells as a way of controlling inflammation. Apremilast may also be used. Individuals with psoriasis may develop neutralizing...
116 KB (12,950 words) - 01:07, 30 May 2025
infections, which have been discovered from the clinical use of roflumilast. Apremilast, a phthalimide derivative that was approved by the U.S. FDA in March 2014...
18 KB (1,905 words) - 21:49, 29 May 2025
and also from Latin word ''planus'', which means flat and even surface. Apremilast is undergoing investigation as a potential treatment. Cutaneous lichen...
63 KB (7,080 words) - 19:14, 24 May 2025
to prevent symptoms such as coughing and excess mucus from worsening Apremilast, used to treat psoriasis and psoriatic arthritis. Crisaborole, used to...
22 KB (2,349 words) - 23:19, 6 May 2025
Gusperimus L04AA22 Abetimus L04AA24 Abatacept L04AA28 Belatacept L04AA32 Apremilast L04AA40 Cladribine L04AA41 Imlifidase L04AA48 Belumosudil L04AA58 Efgartigimod...
3 KB (377 words) - 04:18, 23 December 2024
homeostasis. Recently selective phosphodiesterase 4 (PDE4) inhibitors like apremilast (a thalidomide derivative), roflumilast, and the less subtype-selective...
120 KB (12,868 words) - 06:29, 25 May 2025
Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...
35 KB (3,219 words) - 01:36, 21 April 2025
more potent analog, pomalidomide, is now FDA-approved. Additionally, apremilast was approved by the FDA in March 2014. These thalidomide analogs can be...
76 KB (7,615 words) - 22:21, 29 May 2025
Cancer Multiple myeloma Drug design Thalidomide Lenalidomide Pomalidomide Apremilast Organic chemistry Health crisis Immunomodulation therapy Immunosuppressant...
50 KB (5,487 words) - 19:28, 24 May 2025
inhibitors. Adibendan Aminophylline Aminophylline dihydrate Amipizone Apremilast Arofylline Atizoram Befuraline Bemarinone hydrochloride Bemoradan Benafentrine...
2 KB (137 words) - 00:17, 9 February 2024
(IMiDs) thalidomide and its analogues (lenalidomide, pomalidomide, and apremilast), BCG vaccine, & Covid vaccines [dubious – discuss] Other cytosine phosphate-guanosine...
56 KB (6,093 words) - 16:23, 31 May 2025
drugs include thalidomide, amphotalide, taltrimide, talmetoprim, and apremilast. With a trichloromethylthio substituent, a phthalimide-derived fungicide...
7 KB (497 words) - 00:38, 16 March 2025
(INN) APPG apraclonidine (INN) apramycin (INN) apratastat (USAN, INN) apremilast (USAN, INN) aprepitant Apresazide Apresoline-Esidrix Apresoline Apretude...
8 KB (426 words) - 00:35, 7 March 2025
Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...
83 KB (7,433 words) - 22:11, 29 May 2025
Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...
16 KB (1,732 words) - 21:49, 29 May 2025
Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...
198 KB (19,490 words) - 14:50, 31 May 2025
adalimumab TNF inhibitor bDMARD anakinra IL-1 receptor antagonist bDMARD apremilast phosphodiesterase 4 (PDE4) inhibitor tsDMARD azathioprine Purine synthesis...
10 KB (854 words) - 06:50, 2 November 2024
Pharma (Acq 2015) Catherex (Acq 2015) Nuevolution AB (Acq 2019) Otezla (apremilast) (Acq 2019) Five Prime Therapeutics (Acq 2021) Rodeo Therapeutics Corporation...
102 KB (8,229 words) - 19:55, 29 May 2025
first-in-class treatment option for the management of psoriatic arthritis is apremilast, a small molecule phosphodiesterase-4 inhibitor approved for use by the...
48 KB (5,246 words) - 18:49, 23 May 2025
(lenalidomide) and Pomalyst (pomalidomide) and the immunology drug Otezla (apremilast) accounted for around 90% of the company's total revenue as of 2019. In...
32 KB (2,800 words) - 20:18, 29 May 2025
Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...
15 KB (1,338 words) - 21:54, 29 May 2025
Onercept Pegsunercept Enzyme inhibitors: Apratastat Other inhibitors: Apremilast Bupropion Catechins (green tea) Cannabinoids (cannabis, Echinacea purpurea)...
49 KB (6,227 words) - 17:23, 29 April 2025
prospective studies, as well as one randomized trial for etanercept. Apremilast may also be used to treat oral ulcers associated with Behçet's disease...
49 KB (5,432 words) - 20:06, 29 May 2025
Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...
25 KB (2,242 words) - 12:10, 19 May 2025
Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...
18 KB (1,729 words) - 10:07, 2 June 2024
inflammatory diseases and myelodysplastic syndromes. Apremilast (CC-10004) was found to be a preferable. Apremilast Development of analogs of thalidomide K. Dredge...
1 KB (121 words) - 03:47, 20 October 2023
Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...
11 KB (968 words) - 20:29, 29 May 2025
Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...
15 KB (1,490 words) - 04:22, 18 September 2024
Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...
10 KB (822 words) - 22:30, 29 May 2025