Stromal cell-derived factor 1 (redirect from CXCL12)
also known as C-X-C motif chemokine 12 (CXCL12), is a chemokine protein that in humans is encoded by the CXCL12 gene on chromosome 10. It is ubiquitously...
26 KB (2,930 words) - 15:49, 11 April 2024
alpha-chemokine receptor specific for stromal-derived-factor-1 (SDF-1 also called CXCL12), a molecule endowed with potent chemotactic activity for lymphocytes. CXCR4...
22 KB (2,658 words) - 17:27, 24 April 2024
levels of CXCL12 were found in the human spleens of EMH-positive patients compared to those who were EMH-negative. The high expression of CXCL12, a candidate...
15 KB (1,806 words) - 03:38, 28 November 2023
It is now classified as a chemokine receptor able to bind the chemokines CXCL12/SDF-1 and CXCL11. The protein is also a coreceptor for human immunodeficiency...
15 KB (1,833 words) - 07:36, 5 January 2024
leukocyte migration. These include: CCL14, CCL19, CCL20, CCL21, CCL25, CCL27, CXCL12 and CXCL13. This classification is not strict; for example, CCL20 can act...
30 KB (2,916 words) - 11:52, 3 December 2023
CXCL11. CXCR4 (also known as fusin) is the receptor for a chemokine known as CXCL12 (or SDF-1) and, as with CCR5, is utilized by HIV-1 to gain entry into target...
9 KB (885 words) - 07:16, 30 April 2024
showed disease stabilization via IL-6-regulated downregulation of CCL2, CXCL12 and VEGF. Tocilizumab was first used in large-cell lung carcinoma. In phase...
12 KB (1,289 words) - 19:20, 4 December 2023
CCL28 CXCL CXCL1/KC CXCL2 CXCL3 CXCL4 CXCL5 CXCL6 CXCL7 CXCL8/IL8 CXCL9 CXCL10 CXCL11 CXCL12 CXCL13 CXCL14 CXCL15 CXCL16 CXCL17 CX3CL CX3CL1 XCL XCL1 XCL2...
43 KB (4,990 words) - 05:37, 29 April 2024
ligand 12 (CXCL12) signaling via its receptor C-X-C chemokine receptor type 4 (CXCR4) is also involved in the regulation of SSC fate decisions.CXCL12 is found...
23 KB (2,865 words) - 15:37, 12 April 2024
CCL28 CXCL CXCL1/KC CXCL2 CXCL3 CXCL4 CXCL5 CXCL6 CXCL7 CXCL8/IL8 CXCL9 CXCL10 CXCL11 CXCL12 CXCL13 CXCL14 CXCL15 CXCL16 CXCL17 CX3CL CX3CL1 XCL XCL1 XCL2...
32 KB (3,345 words) - 09:02, 27 March 2024
prevent its activation. Blocking the receptor stops the receptor's ligand, CXCL12, from binding which prevents downstream effects. CXCR4 antagonists are especially...
3 KB (388 words) - 15:47, 30 April 2024
CCL28 CXCL CXCL1/KC CXCL2 CXCL3 CXCL4 CXCL5 CXCL6 CXCL7 CXCL8/IL8 CXCL9 CXCL10 CXCL11 CXCL12 CXCL13 CXCL14 CXCL15 CXCL16 CXCL17 CX3CL CX3CL1 XCL XCL1 XCL2...
34 KB (3,857 words) - 12:02, 15 May 2024
CCL28 CXCL CXCL1/KC CXCL2 CXCL3 CXCL4 CXCL5 CXCL6 CXCL7 CXCL8/IL8 CXCL9 CXCL10 CXCL11 CXCL12 CXCL13 CXCL14 CXCL15 CXCL16 CXCL17 CX3CL CX3CL1 XCL XCL1 XCL2...
52 KB (6,302 words) - 07:19, 27 April 2024
reduce chronic lymphocytic leukemia cell chemotaxis towards the chemokines CXCL12 and CXCL13, and inhibit cellular adhesion following stimulation at the B-cell...
29 KB (2,581 words) - 01:04, 24 May 2024
CCL28 CXCL CXCL1/KC CXCL2 CXCL3 CXCL4 CXCL5 CXCL6 CXCL7 CXCL8/IL8 CXCL9 CXCL10 CXCL11 CXCL12 CXCL13 CXCL14 CXCL15 CXCL16 CXCL17 CX3CL CX3CL1 XCL XCL1 XCL2...
62 KB (7,054 words) - 17:43, 11 April 2024
induced in the context of microenvironmental interactions by CXCR4/SDF1 (CXCL12) chemokine signaling and the molecular function of CD20 has been linked...
22 KB (2,575 words) - 15:14, 21 December 2023
Iroplact Antibodies: Eldelumab (against CXCL10) CXCR4 Agonists: MIF SDF-1 (CXCL12) Ubiquitin Antagonists: Mavorixafor Plerixafor (AMD3100) Antibodies: Ulocuplumab...
98 KB (11,068 words) - 02:47, 20 February 2024
CCL28 CXCL CXCL1/KC CXCL2 CXCL3 CXCL4 CXCL5 CXCL6 CXCL7 CXCL8/IL8 CXCL9 CXCL10 CXCL11 CXCL12 CXCL13 CXCL14 CXCL15 CXCL16 CXCL17 CX3CL CX3CL1 XCL XCL1 XCL2...
14 KB (1,637 words) - 02:07, 3 December 2023
and CXCL12. Critical for anti-tumor immunity are cytotoxic CD8+ T cells. CAFs decrease their infiltration into tumor by releasing chemokine CXCL12 and...
31 KB (3,583 words) - 11:59, 29 April 2024
director in 2014. Her publications include: Multiple actions of the chemokine CXCL12 on epithelial tumor cells in human ovarian cancer Macrophages induce invasiveness...
6 KB (673 words) - 17:08, 17 May 2024
CCL28 CXCL CXCL1/KC CXCL2 CXCL3 CXCL4 CXCL5 CXCL6 CXCL7 CXCL8/IL8 CXCL9 CXCL10 CXCL11 CXCL12 CXCL13 CXCL14 CXCL15 CXCL16 CXCL17 CX3CL CX3CL1 XCL XCL1 XCL2...
36 KB (4,564 words) - 08:42, 19 February 2024
CCL28 CXCL CXCL1/KC CXCL2 CXCL3 CXCL4 CXCL5 CXCL6 CXCL7 CXCL8/IL8 CXCL9 CXCL10 CXCL11 CXCL12 CXCL13 CXCL14 CXCL15 CXCL16 CXCL17 CX3CL CX3CL1 XCL XCL1 XCL2...
24 KB (2,932 words) - 05:25, 15 February 2024
CCL28 CXCL CXCL1/KC CXCL2 CXCL3 CXCL4 CXCL5 CXCL6 CXCL7 CXCL8/IL8 CXCL9 CXCL10 CXCL11 CXCL12 CXCL13 CXCL14 CXCL15 CXCL16 CXCL17 CX3CL CX3CL1 XCL XCL1 XCL2...
35 KB (3,989 words) - 18:59, 2 April 2024
the pre-TCR to survive. They further need signal from CXCR4 (ligand is CXCL12) which does not serve here to direct migration but as a survival signal...
32 KB (4,109 words) - 19:34, 22 May 2024
CCL28 CXCL CXCL1/KC CXCL2 CXCL3 CXCL4 CXCL5 CXCL6 CXCL7 CXCL8/IL8 CXCL9 CXCL10 CXCL11 CXCL12 CXCL13 CXCL14 CXCL15 CXCL16 CXCL17 CX3CL CX3CL1 XCL XCL1 XCL2...
20 KB (2,264 words) - 06:53, 16 May 2024
CCL28 CXCL CXCL1/KC CXCL2 CXCL3 CXCL4 CXCL5 CXCL6 CXCL7 CXCL8/IL8 CXCL9 CXCL10 CXCL11 CXCL12 CXCL13 CXCL14 CXCL15 CXCL16 CXCL17 CX3CL CX3CL1 XCL XCL1 XCL2...
20 KB (2,192 words) - 23:02, 27 November 2023
Iroplact Antibodies: Eldelumab (against CXCL10) CXCR4 Agonists: MIF SDF-1 (CXCL12) Ubiquitin Antagonists: Mavorixafor Plerixafor (AMD3100) Antibodies: Ulocuplumab...
14 KB (977 words) - 01:45, 18 May 2024
CCL28 CXCL CXCL1/KC CXCL2 CXCL3 CXCL4 CXCL5 CXCL6 CXCL7 CXCL8/IL8 CXCL9 CXCL10 CXCL11 CXCL12 CXCL13 CXCL14 CXCL15 CXCL16 CXCL17 CX3CL CX3CL1 XCL XCL1 XCL2...
21 KB (2,761 words) - 19:32, 11 April 2024
Cell Zone Reticular Cell unknown unknown lymph node None None unknown None CXCL12, TNFSF11 B cell unknown unknown large intestine None None unknown None CD21...
171 KB (1,208 words) - 16:47, 18 May 2024
Responsiveness to the Constitutive Chemokine Stromal Cell–derived Factor 1 (SDF-1)/CXCL12". J. Exp. Med. 198 (5): 823–30. doi:10.1084/jem.20020437. PMC 2194187. PMID 12953097...
34 KB (3,972 words) - 19:54, 25 May 2024