An inotrope or inotropic is a drug or any substance that alters the force or energy of muscular contractions. Negatively inotropic agents weaken the force...

positive inotropic and chronotropic effects on the heart. β2 adrenoceptor stimulation in arteriolar smooth muscle induces vasodilation. Its inotropic and chronotropic...

increases the strength of the heart's contractions, leading to a positive inotropic effect. Generally it has little effect on a person's heart rate. Dobutamine...

without a rise in intracellular calcium. Levosimendan exerts its positive inotropic effect by increasing calcium sensitivity of myocytes by binding to cardiac...

stimulation). Agents that are dromotropic are often (but not always) inotropic and chronotropic. For instance, parasympathetic stimulation is usually...

increased uptake leads to increased myocardial contractility (positive inotropic effect), but the myocardial relaxation, or lusitropy, decreases. This...

reduced ventricular function may not be able to counteract the negative inotropic and chronotropic effects of diltiazem, the result being an even higher...

modulation of olfactory driven behaviors. Both positive and negative inotropic effects on heart muscle Secretion from salivary gland Increase salivary...

Reducing the force of contraction of the myocardium is known as the negative inotropic effect of calcium channel blockers. Slowing down the conduction of electrical...

puncture tries, long duration of cannulation, administration of vasopressor/inotropic agents, and the usage of catheters with side holes. Acoustic angiography...

receptor agonist derived from tetrahydroisoquinoline. It has a positive inotropic effect, suggesting potential use in treatment of chronic heart failure...

used digoxin and digitoxin, deal with the latter, due to their positive inotropic activity. On the other hand, cardiac arrhythmia are changes in heart rate...

by epinephrine and norepinephrine induces a positive chronotropic and inotropic effect on the heart and increases cardiac conduction velocity and automaticity...

and a selective inhibitor of phosphodiesterase 3 (PDE3) with positive inotropic and vasodilator effects. Pimobendan is used in the management of heart...

introduction of digitalis, though it turns out that digitalis has an inotropic effect rather than a chronotropic effect. Beta blockers such as metoprolol...

response to beta-adrenergic stimulation and important in increasing the inotropic response. Phosphorylation of cTnI changes the conformation of the protein...

are considered to have a positive inotropic effect. The ancient herbal remedy digitalis appears to have both inotropic and chronotropic properties that...

for this effect. It is a structural analog of nifedipine with positive inotropic activity, and as an aromatic it is highly lipid soluble. Bay K8644 targets...

prescribed antianginal classes of cardiac drugs. Ivabradine has no apparent inotropic properties and may be a cardiotonic agent. It is used for the symptomatic...

responses, including an increase in heart rate, force of contraction (inotropic effect), conduction speed through electrical pathways in the heart, and...

with packed red blood cells Cardiogenic shock Cardiac output Positive inotropic agents / Chronotropes Distributive shock Sepsis (Septic shock) Vascular...

calcium back in the sarcoplasmic reticulum., Istaroxime is a positive inotropic agent that mediates its action through inhibition of sodium/potassium...

important target of cardiac glycosides (for example digoxin and ouabain), inotropic drugs used to improve heart performance by increasing its force of contraction...

chronotropic and inotropic effects, thereby not precipitating angina pectoris. The latter property (positive chronotropic and inotropic effects) is particularly...

Prednisone, Prednisolone Dexamethasone, Betamethasone Fludrocortisone Positive inotropic agents Cardiac glycosides Strophantin K Convallatoxin Digoxin PDE3 inhibitors...

aggressive fluid management, ventilation, renal replacement therapy and inotropic support), particularly in the case of multiple organ failure. Treatment...

Dopexamine went off-patent in 2010. Dopexamine is used in hospitals as an inotropic agent to reduce exacerbations of heart failure and to treat heart failure...

imbriferous in- sinew Greek ἴς, ἰνός (ís, inós), ἰνίον (iníon) inion, inotrope, inotropic in- (1), il-, im- in, on Latin in illuminate, import, incur, intend, invite...

an amino alcohol which is classified as a cardiac stimulant (positive inotropic action). It also increases coronary blood flow along with mild peripheral...

the type of receptor. For instance, neurotransmitters that bind with an inotropic receptor can alter the excitability of a target cell. Other types of receptors...