• Thumbnail for Interferon-alpha/beta receptor
    The interferon-α/β receptor (IFNAR) is a virtually ubiquitous membrane receptor which binds endogenous type I interferon (IFN) cytokines. Endogenous human...
    24 KB (2,617 words) - 19:43, 7 August 2022
  • Thumbnail for Interferon type I
    pseudogenes. Interferons bind to interferon receptors. All type I IFNs bind to a specific cell surface receptor complex known as the IFN-α receptor (IFNAR)...
    25 KB (3,053 words) - 17:04, 11 July 2025
  • interferon-alpha/beta receptor interferon-gamma receptor Interferon type III receptor Interleukin-10 receptor Interleukin-20 receptor Interleukin-22 receptor Interleukin-28...
    6 KB (616 words) - 00:02, 30 March 2025
  • Thumbnail for Interferon beta-1a
    Interferon beta-1a (also interferon beta 1-alpha) is a cytokine in the interferon family used to treat multiple sclerosis (MS). It is produced by mammalian...
    32 KB (2,851 words) - 23:22, 16 August 2024
  • Thumbnail for IFNAR1
    Interferon-alpha/beta receptor alpha chain is a protein that in humans is encoded by the IFNAR1 gene. The protein encoded by this gene is a type I membrane...
    11 KB (1,344 words) - 04:17, 15 July 2025
  • Thumbnail for Stimulator of interferon genes
    to Interferon-alpha/beta receptor of nearby cells to protect cells from local infection. STING elicits powerful type I interferon immunity against viral...
    24 KB (2,749 words) - 08:44, 4 June 2025
  • Thumbnail for Interferon
    JA, Smith GL (December 2000). "The vaccinia virus soluble alpha/beta interferon (IFN) receptor binds to the cell surface and protects cells from the antiviral...
    63 KB (7,124 words) - 04:51, 12 July 2025
  • Thumbnail for IFNAR2
    Interferon-alpha/beta receptor beta chain is a protein that in humans is encoded by the IFNAR2 gene. The protein encoded by this gene is a type I membrane...
    11 KB (1,400 words) - 21:49, 15 July 2025
  • Thumbnail for Cytokine receptor
    Immunodeficiency (X-SCID). Type II cytokine receptors, whose members are receptors mainly for interferons. Immunoglobulin (Ig) superfamily, which are...
    6 KB (442 words) - 18:18, 21 May 2025
  • Thumbnail for Interferon gamma
    heterodimeric receptor consisting of Interferon gamma receptor 1 (IFNGR1) and Interferon gamma receptor 2 (IFNGR2). IFN-γ binding to the receptor activates...
    56 KB (6,491 words) - 17:37, 16 July 2025
  • Thumbnail for STAT3
    PTEN-Akt-FOXO axis (suppressive) and the leukemia inhibitory factor receptor beta (LIFRbeta)-STAT3 signaling pathway (oncogenic) was shown. Overactivation...
    29 KB (3,485 words) - 06:51, 2 June 2025
  • Thumbnail for TNF receptor superfamily
    archetypal TNF-alpha. In their active form, the majority of TNF receptors form trimeric complexes in the plasma membrane. Accordingly, most TNF receptors contain...
    9 KB (610 words) - 13:48, 14 January 2025
  • Thumbnail for Interferon-gamma receptor
    The interferon-gamma receptor (IFNGR) protein complex is the heterodimer of two chains: IFNGR1 and IFNGR2. It binds interferon-γ, the sole member of interferon...
    8 KB (870 words) - 23:14, 28 May 2024
  • Thumbnail for Murine respirovirus
    2014). "An anti-interferon activity shared by paramyxovirus C proteins: inhibition of Toll-like receptor 7/9-dependent alpha interferon induction". FEBS...
    297 KB (32,094 words) - 22:01, 15 July 2025
  • Thumbnail for Interferon alpha-1
    Interferon alpha-1 is a protein that in humans is encoded by the IFNA1 gene. Leukocyte interferon is produced predominantly by B lymphocytes. Immune interferon...
    25 KB (2,751 words) - 21:50, 15 July 2025
  • Thumbnail for Chromosome 21
    IFNAR1: encoding interferon alpha/beta receptor 1 IFNAR2: encoding interferon alpha/beta receptor 2 IFNGR2: encoding interferon gamma receptor 2 IL10RB: encoding...
    33 KB (3,068 words) - 10:45, 6 June 2025
  • Thumbnail for Vero cell
    viruses. However, they still have the Interferon-alpha/beta receptor, so they respond normally when recombinant interferon is added to their culture media....
    7 KB (837 words) - 22:31, 29 May 2025
  • Thumbnail for Tyrosine kinase 2
    region of Tyk2 sustains the level of interferon alpha receptor 1, a component of the interferon alpha/beta receptor". Proceedings of the National Academy...
    25 KB (2,850 words) - 04:54, 15 July 2025
  • Thumbnail for Lymphotoxin beta receptor
    Lymphotoxin beta receptor (LTBR), also known as tumor necrosis factor receptor superfamily member 3 (TNFRSF3), is a cell surface receptor for lymphotoxin...
    12 KB (1,508 words) - 17:56, 19 August 2022
  • Thumbnail for Interleukin 1 beta
    interleukin-1 (IL-1): IL-1 alpha and IL-1 beta (this gene). IL-1β precursor is cleaved by cytosolic caspase 1 (interleukin 1 beta convertase) to form mature...
    26 KB (3,273 words) - 08:48, 14 October 2024
  • Thumbnail for Alpha-synuclein
    process of seeded nucleation, alpha-synuclein adopts a cross-beta sheet structure characteristic of amyloid fibrils. The human alpha-synuclein protein consists...
    84 KB (9,503 words) - 20:00, 16 July 2025
  • Thumbnail for Androgen receptor
    of nuclear import of the domain-specific androgen receptor in association with the importin alpha/beta and Ran-guanosine 5'-triphosphate systems". Endocrinology...
    88 KB (9,476 words) - 16:58, 14 July 2025
  • Interferon alfa (INN) or HuIFN-alpha-Le, trade name Multiferon, is a pharmaceutical drug composed of natural interferon alpha (IFN-α), obtained from the...
    7 KB (672 words) - 21:11, 29 May 2025
  • Interferon alpha-n3 (Alferon-N) is a medication consisting of purified natural human interferon alpha proteins used for the treatment of genital warts...
    3 KB (28 words) - 11:55, 15 September 2024
  • Interleukin-28 receptor is a type II cytokine receptor found largely in epithelial cells. It binds type 3 interferons, interleukin-28 A (Interferon lambda 1)...
    10 KB (1,126 words) - 20:57, 24 June 2021
  • Interferon beta-1b is a cytokine in the interferon family used to treat the relapsing-remitting and secondary-progressive forms of multiple sclerosis (MS)...
    13 KB (1,292 words) - 19:17, 6 April 2024
  • Thumbnail for Estrogen receptor alpha
    Estrogen receptor alpha (ERα), also known as NR3A1 (nuclear receptor subfamily 3, group A, member 1), is one of two main types of estrogen receptor, a nuclear...
    58 KB (6,134 words) - 01:39, 12 July 2025
  • Thumbnail for Estrogen receptor beta
    Estrogen receptor beta (ERβ) also known as NR3A2 (nuclear receptor subfamily 3, group A, member 2) is one of two main types of estrogen receptor—a nuclear...
    39 KB (4,526 words) - 06:00, 25 July 2024
  • Interferon alfa-2b is an antiviral or antineoplastic drug. It is a recombinant form of the protein Interferon alpha-2 that was originally sequenced and...
    10 KB (787 words) - 09:47, 9 March 2025
  • Thumbnail for Lymphotoxin alpha
    Lymphotoxin-alpha (LT-α) formerly known as tumor necrosis factor-beta (TNF-β) is a protein that in humans is encoded by the LTA gene. Belonging to the...
    24 KB (2,773 words) - 21:57, 15 July 2025