• Thumbnail for Major basic protein
    Eosinophil major basic protein, often shortened to major basic protein (MBP; also called proteoglycan 2 (PRG2)) is encoded in humans by the PRG2 gene...
    13 KB (1,519 words) - 18:14, 14 July 2025
  • Thumbnail for Eosinophil
    ribonuclease (RNase), deoxyribonucleases (DNase), lipase, plasminogen, and major basic protein. These mediators are released by a process called degranulation following...
    29 KB (3,165 words) - 21:26, 14 July 2025
  • recombinant human pregnancy-associated plasma protein-A and identification of the proform of eosinophil major basic protein as its physiological inhibitor". The...
    5 KB (562 words) - 10:00, 27 March 2024
  • Thumbnail for Eosinophilia
    platelet activating factor), and toxic proteins (e.g. metalloproteinases, major basic protein, eosinophil cationic protein, eosinophil peroxidase, and eosinophil-derived...
    50 KB (5,522 words) - 17:03, 12 June 2025
  • Thumbnail for Myelin basic protein
    Myelin basic protein (MBP) is a protein important in the process of myelination of nerves in the nervous system. The myelin sheath is a multi-layered membrane...
    25 KB (2,980 words) - 18:14, 14 July 2025
  • 1979 Mega base pairs (Mbp) Major basic protein, a protein which in humans is encoded by the PRG2 gene Maltose-binding protein, a part of the maltose/maltodextrin...
    2 KB (305 words) - 16:45, 24 October 2023
  • Thumbnail for Premunition
    the parasites and leads to eosinophil degranulation which releases major basic protein that damages the parasites, and other factors elicit a local inflammatory...
    9 KB (856 words) - 02:23, 17 November 2024
  • Thumbnail for Phagocytosis
    as lysozymes, Bactericidal permeability-increasing protein, Major basic protein and cationic proteins such as defensins. Other antimicrobial peptides are...
    22 KB (2,533 words) - 21:53, 10 July 2025
  • Thumbnail for Protein C
    excess eosinophil-specific granule proteins (such as major basic protein, erythropoietin and eosinophil cationic protein) on the endothelial surface bind...
    47 KB (5,350 words) - 12:03, 11 July 2025
  • Thumbnail for Degranulation
    mechanism, activated eosinophils release preformed mediators such as major basic protein, and enzymes such as peroxidase, following interaction between their...
    6 KB (635 words) - 08:51, 28 July 2024
  • Thumbnail for Allergic inflammation
    degranulate releasing a number of cytotoxic molecules (including Major Basic Protein and eosinophil peroxidase) as well as produce a number of cytokines...
    5 KB (567 words) - 20:42, 29 January 2023
  • Thumbnail for Eosinophil cationic protein
    cationic protein (ECP) also known as ribonuclease 3 is a basic protein located in the eosinophil primary matrix. In humans, the eosinophil cationic protein is...
    19 KB (2,337 words) - 23:05, 12 October 2024
  • Thumbnail for Löffler's syndrome
    damage caused by the damaging effects of eosinophil granule proteins (e.g. major basic protein) is known as Loeffler endocarditis and can be caused by idiopathic...
    9 KB (930 words) - 11:44, 27 October 2024
  • Thumbnail for DNA-binding protein
    involves DNA binding to a complex of small basic proteins called histones. In prokaryotes, multiple types of proteins are involved. The histones form a disk-shaped...
    22 KB (2,637 words) - 06:01, 3 April 2025
  • phosphatase, lactoferrin, lysozyme, NADPH oxidase Eosinophil: cathepsin, major basic protein Basophil: heparin, histamine (not directly cytotoxic) A specific...
    2 KB (203 words) - 17:18, 16 May 2025
  • Thumbnail for Fc receptor
    eosinophils. Activated eosinophils release preformed mediators such as major basic protein, and enzymes such as peroxidase, against which helminths are not...
    42 KB (4,735 words) - 10:51, 22 May 2025
  • Thumbnail for Protein
    Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions...
    105 KB (10,974 words) - 02:46, 10 July 2025
  • The liver plays the major role in producing proteins that are secreted into the blood, including major plasma proteins, factors in hemostasis and fibrinolysis...
    5 KB (485 words) - 09:32, 3 August 2023
  • Thumbnail for Major histocompatibility complex
    polymorphic genes that code for cell surface proteins essential for the adaptive immune system. These cell surface proteins are called MHC molecules. Its name comes...
    58 KB (6,838 words) - 17:51, 11 July 2025
  • 5-oxo-eicosatetraenoic acid), and toxic proteins (e.g. metalloproteinases, major basic protein, eosinophil cationic protein, eosinophil peroxidase, and eosinophil-derived...
    32 KB (3,610 words) - 07:49, 15 July 2025
  • Thumbnail for C-type lectin
    C-type lectin (category Protein domains)
    carbohydrate-binding protein known as a lectin. The C-type designation is from their requirement for calcium for binding. Proteins that contain C-type...
    7 KB (565 words) - 03:34, 24 April 2025
  • Thumbnail for Major capsid protein VP1
    Major capsid protein VP1 is a viral protein that is the main component of the polyomavirus capsid. VP1 monomers are generally around 350 amino acids long...
    11 KB (1,059 words) - 00:01, 3 December 2023
  • Thumbnail for Prion
    Prion (redirect from Cellular prion protein)
    RNA). Prions are mainly twisted isoforms of the major prion protein (PrP), a naturally occurring protein with an uncertain function. They are the hypothesized...
    105 KB (11,333 words) - 11:17, 12 July 2025
  • Thumbnail for Basic helix–loop–helix
    A basic helix–loop–helix (bHLH) is a protein structural motif that characterizes one of the largest families of dimerizing transcription factors. The word...
    14 KB (1,402 words) - 16:06, 27 March 2025
  • Thumbnail for Leucine zipper
    structural motif in proteins. They were first described by Landschulz and collaborators in 1988 when they found that an enhancer binding protein had a very characteristic...
    16 KB (2,049 words) - 20:45, 24 May 2025
  • Granuloma Acute-phase proteins Amyloid SAP SAA Positive Alpha 1-antichymotrypsin Alpha 1-antitrypsin Alpha 2-macroglobulin C-reactive protein Ceruloplasmin C3...
    38 KB (2,656 words) - 20:26, 6 November 2024
  • (e.g. elevated serum levels of eosinophil-derived neurotoxin and major basic protein), and increased expression of a marker for T cell activation, interleukin-2...
    13 KB (1,441 words) - 13:29, 30 May 2025
  • Thumbnail for Acute-phase protein
    Acute-phase proteins (APPs) are a class of proteins whose concentrations in blood plasma either increase (positive acute-phase proteins) or decrease (negative...
    11 KB (1,096 words) - 14:00, 24 December 2023
  • Thumbnail for Major intrinsic proteins
    Major intrinsic proteins comprise a large superfamily of transmembrane protein channels that are grouped together on the basis of homology. The MIP superfamily...
    23 KB (2,816 words) - 02:11, 29 November 2023
  • Thumbnail for Proteolipid protein 1
    expression may be regulated by MITF. Proteolipid protein 1 has been shown to interact with Myelin basic protein. PLP2 GRCh38: Ensembl release 89: ENSG00000123560...
    9 KB (1,166 words) - 15:32, 4 February 2022