The mevalonate pathway, also known as the isoprenoid pathway or HMG-CoA reductase pathway is an essential metabolic pathway present in eukaryotes, archaea...

The non-mevalonate pathway—also appearing as the mevalonate-independent pathway and the 2-C-methyl-D-erythritol 4-phosphate/1-deoxy-D-xylulose 5-phosphate...

by two distinct metabolic pathways: the mevalonate (MVA) pathway and the non-mevalonate (MEP) pathway. These two pathways are mutually exclusive in most...

variants in the gene for mevalonate kinase, which is part of the mevalonate pathway, an important cellular metabolic pathway. Indeed, similar fever attacks...

non-mevalonate pathway (MEP pathway) uses pyruvate and glyceraldehyde 3-phosphate as substrates to produce IPP and DMAPP. During diseases pathways otherwise...

3-hydroxy-3-methylglutaryl coenzyme A, is an intermediate in the mevalonate and ketogenesis pathways. It is formed from acetyl CoA and acetoacetyl CoA by HMG-CoA...

enzyme in the Mevalonate pathway, it catalyzes the phosphorylation of Mevalonic acid to produce Mevalonate-5-phosphate. A reduction in mevalonate kinase activity...

is an isoprenoid precursor. It is a product of both the mevalonate pathway and the MEP pathway of isoprenoid precursor biosynthesis. It is an isomer of...

final step in the mevalonate pathway. The mevalonate pathway is responsible for the biosynthesis of isoprenoids from acetate. This pathway plays a key role...

the classical, HMG-CoA reductase pathway (commonly called the mevalonate pathway) and in the non-mevalonate MEP pathway of isoprenoid precursor biosynthesis...

and archaea, the mevalonate pathway produces these compounds from acetyl-CoA, while in plants and bacteria the non-mevalonate pathway uses pyruvate and...

mutation. Mevalonic acid is a precursor in the biosynthetic pathway known as the mevalonate pathway that produces terpenes and steroids. Mevalonic acid is...

competitively inhibiting HMG-CoA reductase, the rate-limiting enzyme of the mevalonate pathway. Because statins are similar in structure to HMG-CoA on a molecular...

(NADH-dependent, EC 1.1.1.88; NADPH-dependent, EC 1.1.1.34) of the mevalonate pathway, the metabolic pathway that produces cholesterol and other isoprenoids. HMGCR...

3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonate, this is an early step in the mevalonate pathway catalyzed by HMG-CoA reductase. Through a complicated...

This reaction comprises the second step in the mevalonate-dependent isoprenoid biosynthesis pathway. HMG-CoA is an intermediate in both cholesterol synthesis...

participate in the biosynthesis pathway were interfered with by RNA interference methods. The mevalonate pathway (MVA pathway) is responsible for producing...

acid is an intermediate in the Mevalonate pathway. Miziorko, Henry M. (2011-01-15). "Enzymes of the mevalonate pathway of isoprenoid biosynthesis". Archives...

and archaea, the mevalonate pathway produces these compounds from acetyl-CoA, while in plants and bacteria the non-mevalonate pathway uses pyruvate and...

cholesterol via the mevalonate pathway. Leucine is an essential amino acid in the diet of animals because they lack the complete enzyme pathway to synthesize...

occurs by a complex 37-step process. This begins with the mevalonate or HMG-CoA reductase pathway, the target of statin drugs, which encompasses the first...

secoiridoid monoterpene synthesized from geranyl pyrophosphate in the mevalonate pathway. Secologanin then proceeds with dopamine or tryptamine to form ipecac...

4-phosphate pathway (MEP pathway, also called the non-mevalonate pathway) in the chloroplasts of plants. One of the two end-products of MEP pathway, dimethylallyl...

involve the mevalonate pathway (MVA) and the cyclization of farnesyl diphosphate (FDP). It is not clear whether the non-mevalonate pathway can also contribute...

key step in the biosynthesis of isoprenoids through the mevalonate pathway and the MEP pathway. isopentenyl diphosphate ⇌ {\displaystyle \rightleftharpoons...

Taraxasterol (anthesterin) is a triterpene derived from the mevalonate pathway and is found in dandelions. The precursor for the biosynthesis of taraxasterol...

: 304–305  synthesized in animals from plant-derived carotenoids via the mevalonate pathway, and ascorbic acid (vitamin C),: 492–493  which is synthesized from...

compounds are biosynthesized partly through the phenylpropanoid pathway and the mevalonate pathway, which is biosynthesized by a coupling of dimethylallyl pyrophosphate...

intermediate on the MEP pathway (non-mevalonate pathway) of isoprenoid precursor biosynthesis. It is the first committed metabolite on that pathway on the route...

family is a family of enzymes which participate in the mevalonate pathway, the metabolic pathway that produces cholesterol and other isoprenoids. There...