The norepinephrine transporter (NET), also known as noradrenaline transporter (NAT), is a protein that in humans is encoded by the solute carrier family...
33 KB (3,478 words) - 15:43, 11 January 2025
competitively and/or noncompetitively inhibiting the norepinephrine transporter (NET) and dopamine transporter (DAT). NDRIs are used clinically in the treatment...
5 KB (463 words) - 05:51, 28 January 2025
three major classes are serotonin transporters (SERTs), dopamine transporters (DATs), and norepinephrine transporters (NETs) and are responsible for the...
21 KB (2,342 words) - 15:34, 14 September 2024
cortex, where evidence points to a possibly larger role of the norepinephrine transporter. DAT is implicated in a number of dopamine-related disorders,...
84 KB (9,201 words) - 10:39, 12 December 2024
depression and attention deficit hyperactivity disorder (ADHD). The norepinephrine transporter (NET) serves as the fundamental mechanism for the inactivation...
34 KB (3,807 words) - 20:19, 12 January 2025
Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and...
60 KB (6,685 words) - 20:12, 20 May 2025
neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline) by blocking the action of the norepinephrine transporter (NET). This in turn...
7 KB (678 words) - 15:01, 12 December 2024
inhibitors (SSRIs) and norepinephrine reuptake inhibitors (NRIs), which act upon single neurotransmitters. The human serotonin transporter (SERT) and noradrenaline...
84 KB (8,211 words) - 06:58, 1 May 2025
Ampreloxetine (category Norepinephrine reuptake inhibitors)
(NOH). It shows high affinity for both the norepinephrine transporter (NET) and the serotonin transporter (SERT), with 4-fold selectivity for the NET...
5 KB (335 words) - 13:52, 4 December 2024
Dopamine reuptake inhibitor (redirect from Dopamine transporter "inverse agonist")
very selective for the dopamine transporter, with little to no effect on the norepinephrine and serotonin transporters 4-Hydroxy-1-methyl-4-(4-methylphenyl)-3-piperidyl...
19 KB (1,930 words) - 01:50, 6 March 2025
significant association. Attempts to find a correlation between norepinephrine transporter polymorphisms and depression have yielded negative results. One...
128 KB (15,013 words) - 05:13, 28 April 2025
epinephrine and norepinephrine; subtypes include α1, α2, β1, β2, and β3 receptors Adrenergic transporter (norepinephrine transporter), a protein transporting...
3 KB (286 words) - 18:10, 25 July 2024
Monoamine transporters, including: Dopamine transporter (DAT) Norepinephrine transporter (NET) Serotonin transporter (SERT) Vesicular monoamine transporter 1...
9 KB (988 words) - 00:34, 19 August 2023
simultaneous inhibition of the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT), respectively, increasing their...
138 KB (16,223 words) - 07:48, 6 May 2025
A norepinephrine releasing agent (NRA), also known as an adrenergic releasing agent, is a catecholaminergic type of drug that induces the release of norepinephrine...
18 KB (1,747 words) - 15:13, 13 February 2025
proteins for monoamines (i.e., the dopamine transporter, norepinephrine transporter, and serotonin transporter) in monoamine neurons. Other VMAT2 inhibitors...
29 KB (3,347 words) - 04:21, 10 March 2025
(MATs), which include the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT). This in turn results in an increase...
20 KB (1,388 words) - 21:36, 30 January 2025
Membrane transport protein (redirect from Membrane transporter)
transporters (EAATs) EAAT1 EAAT2 EAAT3 EAAT4 EAAT5 Glucose transporter Monoamine transporters, including: Dopamine transporter (DAT) Norepinephrine transporter...
26 KB (2,656 words) - 14:08, 8 March 2025
Reuptake (category Neurotransmitter transporters)
of the transporters associated with important neurotransmitters within the body were also very similar in sequence to the GABA and norepinephrine transporters...
15 KB (1,897 words) - 08:15, 17 July 2024
autonomic cardiac neuropathy, although reduced expression of the norepinephrine transporter may also result in impaired MIBG reuptake and has been implicated...
99 KB (9,953 words) - 01:05, 21 May 2025
and pinoxepin. Further work on these compounds led to tametraline, a norepinephrine and weaker dopamine reuptake inhibitor. Development of tametraline was...
104 KB (10,669 words) - 04:25, 12 May 2025
methylphenidate lose their ability to elevate brain dopamine but not norepinephrine in dopamine transporter (DAT) knockout mice and have been found to decrease locomotor...
114 KB (12,379 words) - 00:02, 10 May 2025
Methylenedioxypyrovalerone (category Norepinephrine–dopamine reuptake inhibitors)
dopamine transporter is six times stronger than at the norepinephrine transporter and it is virtually inactive at the serotonin transporter. MDPV remained...
35 KB (3,380 words) - 16:23, 9 May 2025
exceptionally difficult to tease apart affinity for the DAT from the norepinephrine transporter (NET) and inhibit the reuptake of dopamine alone. As a result...
16 KB (1,782 words) - 09:16, 31 October 2024
Reuptake inhibitor (redirect from Transporter blocker)
PMID 16770320. Barker, Eric L.; Randy D. Blakely (1995). Norepinephrine and serotonin transporters: molecular targets of antidepressant drugs. In: Psychopharmacology:...
19 KB (1,917 words) - 07:07, 23 November 2024
in vitro inhibitory effects of propofol and ketamine on norepinephrine and serotonin transporter function". J Clin Neurosci. 15 (11): 1264–9. doi:10.1016/j...
119 KB (11,470 words) - 01:26, 21 May 2025
Methylphenidate (category Norepinephrine–dopamine reuptake inhibitors)
monoamine transporters when they are co-administered.[better source needed] Methylphenidate has both dopamine transporter and norepinephrine transporter binding...
155 KB (14,201 words) - 05:20, 20 May 2025
inhibit serotonin transporter (SERT) in the brain and have negligible effects on dopamine transporter (DAT) and norepinephrine transporter (NET). Inhibiting...
51 KB (5,336 words) - 14:09, 1 April 2025
Atomoxetine (category Serotonin–norepinephrine reuptake inhibitors)
Atomoxetine, formerly sold under the brand name Strattera, is a selective norepinephrine reuptake inhibitor (sNRI) medication used to treat attention deficit...
72 KB (6,250 words) - 15:22, 19 May 2025
the monoamine transporters (MATs), including the serotonin transporter (SERT), norepinephrine transporter (NET), and/or dopamine transporter (DAT), causing...
263 KB (22,099 words) - 23:59, 9 May 2025